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J Hypertens:二手烟暴露与非吸烟者心血管危险因素有何关系?

2017-06-07 xing.T MedSci原创

尽管SHSE与心血管疾病的发病率和死亡率风险增加相关,在这个横断面研究中研究人员没有发现SHSE与血压、血脂或空腹血糖水平之间存在相关性。利用尿液中可替宁客观测量并没有改变这种相关性。需要进一步的长期的前瞻性研究来探讨SHSE作为心血管疾病危险因素的影响。

非吸烟者二手烟暴露(SHSE)已被证实与心血管死亡以及缺血性心脏病相关。近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,研究人员进行了一项横断面、以人口为基础的研究,旨在评价通过主观和客观的方法进行测量的SHSE与传统的心血管风险,如血压、血脂、空腹血糖之间的关系。

研究人员提取了7376名从不吸烟的健康成年人的信息,这些参与者尿液中可替宁水平的数据可用,并且来自于2008年-2011年期间韩国国家健康和营养调查。SHSE是通过使用自我报告的问卷调查和尿液中可替宁水平来确定。该研究的主要结局包括SBP和DBP、血脂谱和空腹血糖。

研究人群的平均年龄为45.4±0.4岁,女性为75.2%。自我报告的SHSE与除DBP外的研究结局没有显著相关性,DBP也只是勉强呈正相关性(P=0.060)。未经调整的分析显示较高的可替宁水平与较低的SBP、总胆固醇、低密度脂蛋白胆固醇和甘油三酯相关。所有关联在多元调整后失去统计学意义。空腹血糖与尿液中可替宁正相关,但与可替宁对数变换无关。

尽管SHSE与心血管疾病的发病率和死亡率风险增加相关,在这个横断面研究中研究人员没有发现SHSE与血压、血脂或空腹血糖水平之间存在相关性。利用尿液中可替宁客观测量并没有改变这种相关性。需要进一步的长期的前瞻性研究来探讨SHSE作为心血管疾病危险因素的影响。

原始出处:


Kim, Sehun;et al. Relation between secondhand smoke exposure and cardiovascular risk factors in never smokers.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Relation_between_secondhand_smoke_exposure_and.97705.aspx

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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-13 139****5926

    好文章学习了

    0

  5. 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-12 139****5926

    好文章学习了

    0

  6. 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  7. 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-08 139****5926

    好文章学习了

    0

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