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长城会 2014:我国肺动脉高压生存率已和发达国家相媲美

2014-10-21 长城国际心脏病学会议 长城国际心脏病学会议

阜外心血管病医院徐希奇和荆志成教授等的一项研究表明,我国特发性和家族性肺动脉高压患者的生存率已经有明显改善,平均生存率基本与发达国家水平持平。 该研究发现,2005年前我国处于传统治疗时代,肺动脉高压患者的1年、2年和3年生存率分别为68.0%、56.9%和38.9%,而2005年后的靶向治疗时代则分别提高到89.3%、78.1%、68.2%,与法国近期的生存率结果相近。 患者平均

阜外心血管病医院徐希奇和荆志成教授等的一项研究表明,我国特发性和家族性肺动脉高压患者的生存率已经有明显改善,平均生存率基本与发达国家水平持平。

该研究发现,2005年前我国处于传统治疗时代,肺动脉高压患者的1年、2年和3年生存率分别为68.0%、56.9%和38.9%,而2005年后的靶向治疗时代则分别提高到89.3%、78.1%、68.2%,与法国近期的生存率结果相近。

患者平均生存时间也由30.4月提高到66.2月,基本与发达国家水平持平。2006年后我国肺动脉高压已经开始遵循世界卫生组织制定的肺动脉高压诊治指南,6分钟步行试验和右心导管检查在临床得到广泛应用。

徐希奇介绍,2006年之后,前列环素类似物、磷酸二酯酶抑制剂、内皮素受体拮抗剂等药陆续应用于临床,标志着我国进入靶向治疗时代。

但研究也发现,2006年前后我国确诊肺动脉高压患者的平均年龄无明显差别,分别为35.9岁和34.5岁,心功能较为严重的患者比例均在60%左右,“这表明大多数患者确诊时临床症状已十分明显,并没有得到早诊断。这与基层医院临床医师诊断意识薄弱及肺血管病专科医师队伍缺乏有关。”徐希奇说。


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