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葛兰素史克(GSK)和CureVac制造针对新变体的COVID-19疫苗

2021-02-04 Oranhgy MedSci原创

伦敦-制药商葛兰素史克公司(GlaxoSmithKline)周三表示,将与一家德国生物制药公司合作,开发针对COVID-19新兴变异体的新疫苗,因为人们担心某些突变使该病毒更难以抵抗。

伦敦-制药商葛兰素史克公司(GlaxoSmithKline)周三表示,将与一家德国生物制药公司合作,开发针对COVID-19新兴变异体的新疫苗,因为人们担心某些突变使该病毒更难以抵抗。

 

葛兰素史克计划投资1.5亿欧元(1.81亿美元),以支持总部位于德国图宾根的CureVac的研究,该公司正在开发使用信使RNA攻击该疾病的疫苗。葛兰素史克还表示,它将在今年帮助该公司现有的候选COVID-19疫苗多达1亿剂。

 

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2021年1月7日,星期四,生物技术公司Curevac的徽标带有“ RNA人”的口号在德国图宾根的公司总部展示。通过与制药公司Bayer的合作,Curevac希望能够使用今年夏天推出了Corona疫苗。(Sebastian Gollnow / dpa通过AP)

 

两家公司在一份声明中说:“新兴变异体的增加有可能降低第一代COVID-19疫苗的功效,这就要求加快开发针对新变异体的疫苗的努力,以使流行病领先一步。”

 

宣布此消息之际,全球公共卫生官员对新的病毒变种提出了担忧,这些新的病毒变种更具传染性或对现有疫苗具有抵抗力。尽管病毒会不断发生变异,但大多数变化不会引起太大关注。但是科学家们正在密切追踪这些突变,以确保他们能够快速识别出所关注的变异。

 

英格兰当局本周正在针对性社区进行家中冠状病毒测试,以在新病毒广泛传播并破坏全国疫苗接种计划之前将其扑灭。

 

英国当局希望在八个地区测试约80,000人,该地区最初在南非发现,在与该国没有联系的人或到该国旅行的任何人中发现了几例病例之后,据信这种变异正在蔓延。

 

公共健康官员都在关注南非首次发现变异,因为它包含了现有的疫苗所针对的病毒的特征刺突蛋白的突变。突变可能意味着疫苗针对该变体提供的保护较少。

 

GSK首席执行官艾玛·沃尔姆斯利(Emma Walmsley)在声明中说:“我们认为,下一代疫苗对于持续对抗COVID-19至关重要。” “这项新的合作建立在我们与CureVac的现有关系的基础上,这意味着我们将结合我们在mRNA和疫苗开发方面的科学专长,以促进和加快新的COVID-19候选疫苗的开发。”

 

葛兰素史克(GSK)在周三发布的全年财报中表示,由于政府优先考虑COVID-19疫苗接种计划以及2020年底流感大流行,预计今年上半年疫苗业务将进一步受到影响。

 

它说,这预计将影响成人和青少年的免疫接种,包括Shingrix预防带状疱疹,尤其是在美国。尽管如此,它预计今年下半年会反弹,并且2021年的疫苗收入将持平或略有增长。

 

总体而言,葛兰素史克(GSK)在2020年的销售额增长了1%,达到341亿英镑(460亿美元),净利润增长了21%,达到64亿英镑(96亿美元)。

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    2021-07-06 徐岩
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    2021-02-05 metal分析

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