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Pediatrics:维生素D对胎儿发育的影响

2015-01-14 MedSci MedSci原创译

过去的出生队列研究表明,胎儿环境对出生后健康状况有影响,这为我们提供了非常宝贵的研究数据。但是目前还不明确维生素D水平对胎儿发育的影响。通过对随机挑选社区内901名母婴,研究者对孕18周时维生素D缺乏展开调查,并研究其子女的长期健康结局。纳入的研究对象为1989-1991年在澳大利亚佩斯、澳大利亚西部出生的儿童。研究发现,孕妇中共有36%患维生素D缺乏,即血清25(OH)D含量小于50nmol/L

过去的出生队列研究表明,胎儿环境对出生后健康状况有影响,这为我们提供了非常宝贵的研究数据。但是目前还不明确维生素D水平对胎儿发育的影响。通过对随机挑选社区内901名母婴,研究者对孕18周时维生素D缺乏展开调查,并研究其子女的长期健康结局。纳入的研究对象为1989-1991年在澳大利亚佩斯、澳大利亚西部出生的儿童。研究发现,孕妇中共有36%患维生素D缺乏,即血清25(OH)D含量小于50nmol/L。在调整了协变量后发现,孕妇怀孕时维生素D缺乏与其子女在6岁时肺发育不良、10岁时神经认知障碍、青少年期饮食障碍以及20岁时峰值骨密度降低都显著相关。总的来说,维生素D可能在胎儿肺、脑、骨骼发育中起到至关重要的作用。过去的动物研究认为,维生素D能够促进器官发育。目前亟需对补充维生素D的孕妇进行随访随机对照研究,长期随访其子女的健康状况,从而判断维生素D缺乏的孕妇是否能够通过补充维生素D来改善子女的健康状况,并确立孕妇血清25(OH)D的最佳浓度。原始出处: Hart, P.H., et al., Vitamin d in fetal development: findings from a b

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    2015-10-02 hbwxf
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    2015-02-27 feather89
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    2015-01-16 neurowu
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    2015-01-14 116.226.156.**

    我们自己

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1958404, encodeId=4219195840485, content=<a href='/topic/show?id=766713993a1' target=_blank style='color:#2F92EE;'>#Pediatric#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13993, encryptionId=766713993a1, topicName=Pediatric)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Fri Oct 02 18:22:00 CST 2015, time=2015-10-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637023, encodeId=36d0163e023b1, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Apr 16 07:22:00 CST 2015, time=2015-04-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1705625, encodeId=5a071e056250b, content=<a href='/topic/show?id=e6ab8359eb0' target=_blank style='color:#2F92EE;'>#胎儿发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83597, encryptionId=e6ab8359eb0, topicName=胎儿发育)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b3a031008247, createdName=刘阔, createdTime=Sun Oct 11 13:22:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1725729, encodeId=37861e2572902, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Fri Feb 27 08:22:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1347033, encodeId=8da0134e033c5, content=<a href='/topic/show?id=88713e938c1' target=_blank style='color:#2F92EE;'>#发育#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37938, encryptionId=88713e938c1, topicName=发育)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f4c124, createdName=neurowu, createdTime=Fri Jan 16 08:22:00 CST 2015, time=2015-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14343, encodeId=7584143432e, content=我们自己, beContent=null, objectType=article, channel=null, level=null, likeNumber=140, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=116.226.156.**, createdTime=Wed Jan 14 18:14:00 CST 2015, time=2015-01-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=14338, encodeId=1dfc1433867, content=可以, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=MedSci客户端网友, createdTime=Wed Jan 14 17:44:00 CST 2015, time=2015-01-14, status=1, ipAttribution=)]
    2015-01-14 MedSci客户端网友

    可以

    0

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