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J Hypertens:无创中心血压指标和肱动脉指标与器官损害之间的关系比较!

2018-03-01 xing.T MedSci原创

由此可见,该研究的结果表明中心SBP和PP相比于对应的肱动脉指标并不能改善终末器官损伤的诊断准确性。

近日,高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章,该横断面研究旨在调查基于新型袖带无创监测器检测的中心收缩压和脉压(PP)是否比相应的肱动脉测量指标与高血压靶器官损伤之间的关系更为密切。

研究人员从普通人群中抽取了246名受试者(平均年龄为57.2岁,女性占55.3%)调查了中心与肱动脉SBP和PP与超声心动图测得的左室质量指数(LVMI)、左室肥厚(LVH)、颈动脉内膜中层厚度(IMT)和增加的IMT(IMT≥第七十五百分位数)之间的相关性。

研究人员发现所有血压(BP)指标与LVMI、IMT呈正相关(所有P<0.001)。肱动脉和中心SBP与LVMI(r = 0.42和0.40,差异P=0.19)和IMT(r= 0.32和0.33,P = 0.60)之间存在同样的相关性。然而,肱动脉PP比中心PP与LVMI(r= 0.34和0.27,P = 0.03)和IMT(r = 0.40和0.35,P = 0.04)之间的相关性更强烈。在多变量调整后的Logistic模型中,所有的四个BP指标与LVH和增加的IMT显著相关(所有P≤0.03)。然而,包括肱动脉或中心血流动力学参数在内的logistic回归模型的诊断准确率类似,对于LVH(SBP曲线下面积(AUC):0.74 vs. 0.76,P=0.16;PP的AUC为:0.75 vs. 0.73,P=0.35)和IMT(SBP的AUC为0.61,P=0.67,PP的AUC为0.63 vs. 0.61,P=0.29)。

由此可见,该研究的结果表明中心SBP和PP相比于对应的肱动脉指标并不能改善终末器官损伤的诊断准确性。

原始出处:

Lindroos, Annika S,et al. Relation of blood pressure and organ damage: comparison between feasible, noninvasive central hemodynamic measures and conventional brachial measures.Journal of Hypertension. 2018. https://journals.lww.com/jhypertension/Abstract/publishahead/Relation_of_blood_pressure_and_organ_damage__.97521.aspx

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GetPortalCommentsPageByObjectIdResponse(id=291913, encodeId=0bb02919131c, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu Mar 01 07:12:51 CST 2018, time=2018-03-01, status=1, ipAttribution=)]
    2018-03-01 明月清辉

    谢谢分享.学习了

    0

  8. 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    2018-03-01 龙胆草

    学习谢谢分享

    0

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    2018-03-01 神功盖世

    0

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GetPortalCommentsPageByObjectIdResponse(id=291913, encodeId=0bb02919131c, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu Mar 01 07:12:51 CST 2018, time=2018-03-01, status=1, ipAttribution=)]
    2018-03-01 飛歌

    学习了很有用

    0

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