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Lancet Psychiatry:万人研究提示,中年孤独,老年更容易抑郁!

2020-12-30 Freeman MedSci原创

基线时孤独感得分较高与抑郁症状严重程度得分较高相关

 
在老年人中,抑郁症是非常常见的,在全世界范围内初步估计的发病率为4-9%。过去15年的数据表明,老年人中的抑郁症患病率正在上升。更好地识别抑郁症可改变的风险因素,将为公共卫生和临床预防措施提供信息。
 
孤独是一种痛苦的情绪状态,是由一个人渴望的有意义的社会关系和他们认为自己拥有的关系之间的落差造成的。孤独感与社会关系的其他方面有关,但又有所不同,比如客观的社会隔离和自己主观感知的社会支持。在英国,大约三分之一的50岁及以上的人报告说他们感到孤独,部分原因可能是由于退休、身体和认知能力下降、丧失亲友、社交网络减少以及社会角色的丧失等因素。孤独感和抑郁症之间有很大的重叠,但又有所不同。孤独可能带来一定的社会、认知和生物后果,并因此增加随后患抑郁症的风险。
University College London (UCL) 的Siu Long Lee等人,基于著名的English Longitudinal Study of Ageing (ELSA),对近万个50岁以上的人,进行每2年一次,累积7次,共12年的随访研究。他们用加州大学洛杉矶分校孤独量表(R-UCLA)评估孤独状况。用Centre for Epidemiologic Studies Depression Scale (CES-D)来评估抑郁情况。
 
结果显示:孤独感得分每增加1分,抑郁症状严重程度得分增加0.16(95% CI 0.13-0.19)相关。我们估计,抑郁症与孤独感相关的人群归因分数在随访1年时为18% ,在最后随访时为11% 。这表明,如果消除了孤独感,11-18% 的抑郁症病例可能得到预防。尽管随访时间越长,孤独感和抑郁症状之间的联系越小,但是在12年的随访后,孤独感和抑郁症状之间的联系仍然存在。
 
这个研究的主要意义在于:在50岁及以上的成年人中,基线时孤独感得分较高与抑郁症状严重程度得分较高相关。提供减少孤独感的干预措施,能预防或减少老年人的抑郁症。
 
 
 

 
 
 
 

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    2021-06-13 howi
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    2020-12-30 rayms

    人是群居动物,与人为乐是生活的第一要义

    0

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    2020-12-30 goodbing

    顶刊就是不一样,质量很高,内容精彩!学到很多

    0

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