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Nat Commun:发现壁虎爬墙及断尾再生相关基因

2015-11-27 佚名 生物谷

图片来自:www.hdwallpapersnew.net 多疣壁虎(Gekko japonicus)的基因序列发表在了本周的Nature Communications上。该研究由中国南通大学、深圳华大基因、中科院成都生物研究所和James D. Watson基因组科学研究所(杭州)的联合课题组共同完成。 此项研究是迄今为止规模最大的爬行动物基因组测序,定位了与壁虎爬上光滑的表面、重生尾巴和

图片来自:www.hdwallpapersnew.net

多疣壁虎(Gekko japonicus)的基因序列发表在了本周的Nature Communications上。该研究由中国南通大学、深圳华大基因、中科院成都生物研究所和James D. Watson基因组科学研究所(杭州)的联合课题组共同完成。

此项研究是迄今为止规模最大的爬行动物基因组测序,定位了与壁虎爬上光滑的表面、重生尾巴和晚间惊人视力的相关基因。

南通大学神经再生重点实验室的顾晓松和他的研究团队,对于一只成年雄性壁虎进行了全基因组测序,获得了一个25.5亿对碱基的基因组序列。这当中,有22487个基因,他们确定了它们的位置和功能。他们发现了β-角蛋白基因家族的规模增加,这被认为和壁虎有黏性的脚底触毛的形成有关。而这种爬行足底的毛,让壁虎能够捕捉猎物,并且黏附在光滑表面上。

研究团队还分析了与尾巴再生相关的基因的演化,并且确定了与这些动物从昼行转化成夜行生活方式相关的特定基因,这些基因被称为视蛋白基因。这些研究结果有助于深入了解壁虎的演化史,也可能有助于仿生粘合技术的发展,以及帮助我们理解再生过程的遗传基础。

原文出处:

Yan Liu,et al,Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration.Nat Commun.2015 

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    2016-05-01 liuli5079
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    2015-12-30 liye789132251
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