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Ann Rheum Dis:城市与农村中轴型脊柱关节炎患者预后和治疗反应的比较

2020-06-13 xiangting MedSci原创

农村地区axSpA患者报告的疾病对工作效率的影响更大。

这项研究旨在探讨农村和城市地区中轴型脊柱关节炎(axSpA)患者在临床和患者报告结局(包括工作)方面的差异。

采用顺序、解释性混合方法设计,使用英国风湿病学会强直性脊柱炎生物登记数据:(a)表征农村和城市地区axSpA参与者的特征,和(b)评估开始生物治疗后结局的差异(阶段1)。半结构化访谈(阶段2)进一步探讨了阶段1的结果。

农村地区axSpA患者的年龄较大,更可能从事体力劳动。使用生物制剂的患者中,对生物制剂的反应没有差异,但是调整年龄、性别和局部剥夺后,农村居民则报告了更多的出勤和整体工作障碍。可以通过考虑疾病活动性、疲劳、躯体机能和工作类型的个体差异来解释工作影响。访谈强调了临床因素、背景因素(工作环境、工作要求)和工作障碍之间的复杂关系。工作能力和在执行什么任务、何时以及如何执行方面的灵活性很重要。来自雇主的支持不同,医疗保健专业人员通常被认为不支持的。

农村地区axSpA患者报告的疾病对工作效率影响更大。需要采取新措施来捕捉重要的背景因素,并综合确定长期疾病对工作的影响。未来的欧洲抗风湿病联盟axSpA指南应包括将工作支持作为优化axSpA患者生活质量的目标。

原始出处:

Rosemary J Hollick. Outcomes and treatment responses, including work productivity, among people with axial spondyloarthritis living in urban and rural areas: a mixed-methods study within a national register. Ann Rheum Dis. June 2020.

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    2020-06-15 daviiliu

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