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JCO:防晒霜也能防癌!

2016-09-15 Mechront 译 MedSci原创

黑色素瘤,又称恶性黑色素瘤,是来源于黑色素细胞的一类恶性肿瘤,常见于皮肤,亦见于黏膜、眼脉络膜等部位。黑色素瘤是皮肤肿瘤中恶性程度最高的瘤种,容易出现远处转移。 研究者进行了一项大型队列研究,评估防晒霜的使用与黑色素瘤风险之间的关系,且对不同防晒系数(SPF)的防晒霜进行了比较(高SPF vs 低SPF)。 我们使用的数据来自挪威妇女和癌症研究,这是一项纳入了143844名女性的以人口

黑色素瘤,又称恶性黑色素瘤,是来源于黑色素细胞的一类恶性肿瘤,常见于皮肤,亦见于黏膜、眼脉络膜等部位。黑色素瘤是皮肤肿瘤中恶性程度最高的瘤种,容易出现远处转移。

研究者进行了一项大型队列研究,评估防晒霜的使用与黑色素瘤风险之间的关系,且对不同防晒系数(SPF)的防晒霜进行了比较(高SPF vs 低SPF)。

我们使用的数据来自挪威妇女和癌症研究,这是一项纳入了143844名女性的以人口为基础的前瞻性研究,参与者年龄在40-75岁之间,随访1532247人年,发生了722例黑色素瘤。使用多变量Cox比例风险回归模型,评估防晒霜的使用(从不、SPF < 15、SPF ≥ 15)与黑色素瘤风险之间的关系。

数据显示,防晒霜使用者有更多的晒伤和日光浴假期,更有可能使用室内日光浴设备。防晒霜使用者中,SPF ≥ 15 vs SPF < 15,可显著降低黑色素瘤风险(HR 0.67; 95% CI, 0.53 to 0.83)。40-75岁女性,使用SPF ≥ 15的防晒霜,可能会降低18% (95% CI, 4% to 30%)的黑色素瘤风险。

结果表明,使用防晒霜对黑色素瘤的预防是真的有效,并且SPF ≥ 15的防晒霜效果会好于SPF < 15。

原始出处:

Ghiasvand R.et al.Sunscreen Use and Subsequent Melanoma Risk: A Population-Based Cohort Study.J Clin Oncol. 2016 Sep 12. pii: JCO675934. [Epub ahead of print]

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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2017-05-25 lidong40
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    2016-10-04 Carlos007

    使用防晒霜对黑色素瘤的预防是真的有效,并且SPF ≥ 15的防晒霜效果会好于SPF < 15。感觉研究没什么意义

    0

  3. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-10-04 Carlos007

    感觉使用防晒霜对黑色素瘤的预防是真的有效,并且SPF ≥ 15的防晒霜效果会好于SPF < 15。

    0

  4. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-10-04 Carlos007

    其实就是防紫外线啊!紫外线的危害不就是致癌嘛……

    0

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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-17 忠诚向上

    好好学习一下

    0

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  8. [GetPortalCommentsPageByObjectIdResponse(id=1891303, encodeId=614b1891303e3, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Thu May 25 08:09:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=139983, encodeId=d1051399832e, content=使用防晒霜对黑色素瘤的预防是真的有效,并且SPF ≥ 15的防晒霜效果会好于SPF < 15。感觉研究没什么意义, beContent=null, objectType=article, channel=null, level=null, likeNumber=165, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160923/IMG57E54D670B3C08868.jpg, createdBy=e90b1956497, 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authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Sep 16 10:53:00 CST 2016, time=2016-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=128166, encodeId=4492128166d2, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:40:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=128163, encodeId=694612816393, content=学习了,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-16 虈亣靌

    学习了,赞一个!!!!!!

    0

  9. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  10. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Thu Sep 15 20:39:00 CST 2016, time=2016-09-15, status=1, ipAttribution=)]
    2016-09-15 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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