PLoS Genet：偶然产生的新基因或带来进化创新

2016-01-07 佚名生物谷

图片来源：medicalxpress.com 新基因通常会在进化的过程中不断出现，那么是什么驱动了这一过程呢？近日一项刊登在PLoS Genetics上的研究报告中，来自西班牙加泰罗尼亚高等研究院（ICREA）等处的研究人员通过研究发现，基因组中特定元件组合的偶然出现或许会导致新型基因的产生。在每一个基因组中都存在多套基因，其对于特殊的物种非常重要，这项研究中，科学家们首次鉴别出了对人

图片来源：medicalxpress.com

新基因通常会在进化的过程中不断出现，那么是什么驱动了这一过程呢？近日一项刊登在PLoS Genetics上的研究报告中，来自西班牙加泰罗尼亚高等研究院（ICREA）等处的研究人员通过研究发现，基因组中特定元件组合的偶然出现或许会导致新型基因的产生。

在每一个基因组中都存在多套基因，其对于特殊的物种非常重要，这项研究中，科学家们首次鉴别出了对人类或黑猩猩都非常特殊且重要的成千上万个基因，随后研究人员对短尾猴机体的基因组进行筛查，发现短尾猴相对应的基因组序列中相关的元件基团明显减少了，二者这些可以被蛋白质识别的元件基团可以激活基因的表达，而该过程对于新基因的形成非常关键。

基因的重新形成通常会开始于非激活的基因组部分，而这种可能性是非常小的，本文研究表明，机体遗传物质发生正常的突变或许足以帮助解释基因形成的原因；一旦进行表达，基因就会扮演新型分子功能进化的基本物质。

最后研究者Ruiz-Orera J博士说道，这项研究中我们鉴别出了多个候选的人类蛋白，这些特殊蛋白同其它任何已知的蛋白并无相似之处，而其功能的发挥非常神秘，我们还需要后期大量的研究来阐明这些特殊蛋白的功能及作用机制。

原始出处：

Jorge Ruiz-Orera, Jessica Hernandez-Rodriguez,et at.Origins of De Novo Genes in Human and Chimpanzee.PLoS Genet.2015

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评论区 (7)

#插入话题

插入图片

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2016-05-09 江川靖瑶

#Genet#

56 0
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2016-11-15 cy0324

#Gene#

67 0
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2016-05-24 canlab

#NET#

45 0
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2016-01-09 lilianxiang

#创新#

0 0
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2016-01-09 12498b3em14(暂无昵称)

#新基因#

49 0
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2016-01-08 木醇阳

不错哦

116 0
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2016-01-08 zhuzhuba1

牛

130 0

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