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牙周病可能与老年人肾功能下降有关

2012-04-10 范振光 手牵手博客

    早期检查出肾功能下降可有助于预防肾脏疾病向肾功能衰竭发展,并预防发生心血管事件。有研究显示肾功能和牙周疾病存在显著联系。然而,还没有相关的纵向研究,也没有相关研究在日本进行。为此,日本新泻大学口腔健康系的Masanori Iwasaki等在日本社区老年人中做了一个纵向研究,以分析牙周疾病对肾功能的影响。       该队列研究样本来自一

    早期检查出肾功能下降可有助于预防肾脏疾病向肾功能衰竭发展,并预防发生心血管事件。有研究显示肾功能和牙周疾病存在显著联系。然而,还没有相关的纵向研究,也没有相关研究在日本进行。为此,日本新泻大学口腔健康系的Masanori Iwasaki等在日本社区老年人中做了一个纵向研究,以分析牙周疾病对肾功能的影响。       该队列研究样本来自一项关于老化的纵向跨学科研究,于2003年纳入317名(男性166人,女性151人)年龄为75岁的老年人。牙周发炎的表面积(PISA)反应发炎的牙周组织数量,计算每个人的PISA,根据每个人的PISA把他们分为4个组(按四分位数分),然后再分为两个组,即最高四分位数组和其它3个组。把研究的首要终点设为以eGFR计算的肾功能下降。       结果发现经过2年随访,45人肾功能下降。PISA最高四分位组人群累积肾功能下降率显著高于其它组,比值比为2.24。该研究结果提示牙周疾病可能是日本老年人肾功能下降的一个风险因子。   来源:Am J Kidney Dis. 2012 Feb;59(2):202-9.

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    2013-02-28 yese
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