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Hypertension:超声心动图在高血压与非高血压人群的预后价值!

2018-02-27 xing.T MedSci原创

由此可见,在高血压患者中,除了已知的危险因素外,加入左心室质量指数也可增加了对预后的预测价值。在正常个体中,将整体纵向应变加入到已知的危险因素中也可增加预测价值。

高血压可能是最重要的心血管危险因素。很少有研究评估超声心动图对高血压患者的预后价值。近日,心血管权威杂志Hypertension上发表了一篇研究文章,这项研究探讨了高血压和无高血压的人群将超声心动图参数加入到已知危险因素的增量预测价值。

该研究共对1294名普通个人进行了健康检查和超声心动图评估,包括二维斑点追踪。研究结局为缺血性心脏病和心力衰竭的复合终点。

高血压患病率为38.3%。在平均随访12.5年(四分位距为9.4-12.8年),222名(17.2%)受试者发生了研究结局。在这222次事件中,145次(65%)发生于高血压患者中,而77次(35%)发生于非高血压个体,对应的发病率分别为32/(1000人每年)和8/(1000人每年)。随访率为100%,多变量调整后,只有左心室重量指数可预测高血压患者的预后,而只有整体纵向应变可预测非高血压个体的结局。在高血压患者中,左室质量指数的预测价值递增,高于 SCORE评分和异常ECG状态。非高血压个体整体纵向应变的预后价值递增,也高于 SCORE评分和异常ECG状态。高血压可改变超声心动图对一般人群心血管结局的预后预测价值。

由此可见,在高血压患者中,除了已知的危险因素外,加入左心室质量指数也可增加了对预后的预测价值。在正常个体中,将整体纵向应变加入到已知的危险因素中也可增加预测价值。

原始出处:


Daniel Modin,et al. Prognostic Value of Echocardiography in Hypertensive Versus Nonhypertensive Participants From the General Population.Hypertension.2018. https://doi.org/10.1161/HYPERTENSIONAHA.117.10674

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    2018-10-29 feather89
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    2018-02-27 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0

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