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盘点:2016年全新肺癌指南一览

2016-08-29 MedSci MedSci原创

一二三四五六七

肺癌是最常见的肺原发性恶性肿瘤,绝大多数肺癌起源于支气管粘膜上皮,故亦称支气管肺癌。其中占肿瘤之首,吸烟发病率高,近50多年来,世界各国特别是工业发达国家,肺癌的发病率和病死率均迅速上升,死于癌病的男性病人中肺癌已居首位。为此,梅斯小编对2016年发布的关于肺癌的指南进行整理,与大家分享。

一、2017 NCCN临床实践指南:肺癌筛查(2017.V1)

2016年8月,美国国家综合癌症网络(NCCN)发布了肺癌筛查指南2017年第一版,指南更新摘要如下: 风险评估,筛查结果,实性结节初始低剂量CT扫描,部分实性结节初始低剂量CT扫描,非实性结节初始低剂量CT扫描,随访或每年低剂量CT扫描新发结节,随访或每年低剂量CT扫描实性结节,随访或每年低剂量CT扫描部分实性结节,随访或每年低剂量CT扫描非实性结节,多种非实性结节,低剂量CT扫描采集存储解释以及结节报告,肺癌筛查风险/获益。(文章详见——2017 NCCN临床实践指南:肺癌筛查(2017.V1)

二、2017 NCCN临床实践指南:小细胞肺癌(2017.V1)

2016年8月,美国国家综合癌症网络(NCCN)发布了小细胞肺癌指南2017年第1版,指南更新摘要如下:小细胞肺癌,初始评估和分期,局限期检查和治疗,初始治疗后反应评估,监测,进展期疾病的后续治疗和股息治疗,手术切除原则,支持指南原则,系统治疗原则,放射治疗原则,肺神经内分泌肿瘤,检查和初始治疗,复制治疗,系统治疗原则,分期。(文章详见——2017 NCCN临床实践指南:小细胞肺癌(2017.V1)

三、2016 中国埃克替尼治疗非小细胞肺癌专家共识(2016年版)

为进一步规范、指导临床医生更好的使用埃克替尼,更好地为肺癌患者服务,中国药学会抗肿瘤药物专业委员会组织全国专家,结合我国多个肺癌诊疗规范及治疗指南,于2015年制定了《中国埃克替尼治疗非小细胞肺癌专家共识(2015版)》。一年来,埃克替尼新的研究结果不断问世,为了将这些新的研究成果纳入专家共识,中国药学会抗肿瘤药物专业委员会组织专家将原专家共识进行了更新,制定了《中国埃克替尼治疗非小细胞肺癌专家共识(2016年版)》。(文章详见——2016 中国埃克替尼治疗非小细胞肺癌专家共识(2016年版)

四、2016 非小细胞肺癌靶向药物治疗相关基因检测的规范建议

肺癌是世界范围内发病率及病死率均居于首位的恶性肿瘤 ,其中NSCLC约占85%左右。随着对其分子途径探索的逐步深入和相对应的靶向药物的不断出现,给其中的部分晚期患者带来了新的希望。(文章详见——非小细胞肺癌靶向药物治疗相关基因检测的规范建议

五、2016 NCCN临床实践指南:肺癌筛查(2016.V2)

2016年4月,美国国家综合癌症网络(NCCN)发布了肺癌筛查指南2016年第2版,指南更新摘要如下:风险评估,筛查结果,实性或部分实性结节的评估以及随访筛查结果,磨玻璃阴影/磨玻璃结节/非实性结节的评估及随访筛查结果,多发性磨玻璃阴影/磨玻璃结节/非实性结节,新发结节的评估及随访筛查结果,低剂量CT采集、存储、解释和结节报告,肺癌筛查的风险/获益。文章详见——NCCN临床实践指南:肺癌筛查(2016.V2)

六、2016 中国晚期原发性肺癌诊治专家共识(2016年版)

病理诊断是肺癌诊断的金标准,与此同时,近年来肺癌的分子遗传学研究取得了显著进展,基于遗传特征的分子分型使晚期肺癌的治疗步入了个体化分子靶向治疗时代。正是在这样的背景下,2015年世界卫生组织(World Health Organization, WHO)发表了肺肿瘤组织学的新分类。与2004年分类相比,其中一项最主要的变化就是在晚期肺癌患者的个体化治疗策略中强调了分子遗传学的作用。国家卫生和计划生育委员会医政医管局委托中国抗癌协会肿瘤临床化疗专业委员会制定了《中国原发性肺癌诊疗规范(2015年版)》,但是近些年晚期肺癌的治疗进展迅速,治疗选择显著增多,为进一步提高我国晚期肺癌的诊疗水平,改善晚期肺癌患者的预后,中国医师协会肿瘤医师分会和中国抗癌协会肿瘤临床化疗专业委员会组织全国专家,结合近年来肺癌病理、分子遗传学及诊断和治疗的最新研究成果,制定了《中国晚期原发性肺癌诊疗专家共识(2016年版)》。(文章详见——中国晚期原发性肺癌诊治专家共识(2016年版)

七、2016 NCCN:非小细胞肺癌指南-证据块(2016.V4)

2016年2月,美国国家综合癌症网络(NCCN)发布了非小细胞肺癌临床指南2016.V4证据块。主要内容涉及:NCCN证据块的定义,肺癌的预防和筛查,肺癌的临床表现和风险评估,初始评估和临床分期,各期肺癌的评估和治疗,监测,复发治疗和随访,转移性疾病的系统治疗,病理检查原则,手术治疗原则,放射治疗原则等。(文章详见——2016 NCCN:非小细胞肺癌指南-证据块(2016.V4)

八、2016 NCCN临床实践指南:非小细胞肺癌 (2016.V4)

2016年2月,美国国家综合癌症网络(NCCN)发布了非小细胞肺癌临床指南2016.V4。(文章详见——2016 NCCN临床实践指南:非小细胞肺癌 (2016.V4)

九、2016 NCCN 小细胞肺癌指南(2016.V1)

2016年2月,美国国家综合癌症网络(NCCN)发布了小细胞肺癌临床指南2016第一版。(文章详见——2016 NCCN 小细胞肺癌指南(V1)

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17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-26 1e10c84am36(暂无匿称)

    文章很好值得关注

    0

  2. 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17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-18 1e10c84am36(暂无匿称)

    不错哦继续关注

    0

  3. 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createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 18 15:17:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125736, encodeId=8762125e369d, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Tue Sep 13 21:24:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111457, encodeId=18ad11145e45, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 12:47:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108901, encodeId=92d510890151, content=嗯,不错,,要认真读一遍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Sep 01 13:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108647, encodeId=8b3410864eff, content=指南应该是工作的规范,但不应该成为一种束缚, beContent=null, objectType=article, channel=null, level=null, 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encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-13 1e0d5b16m97(暂无匿称)

    不错的知识点学到了很多

    0

  4. 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17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 12:47:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108901, encodeId=92d510890151, content=嗯,不错,,要认真读一遍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Sep 01 13:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108647, encodeId=8b3410864eff, content=指南应该是工作的规范,但不应该成为一种束缚, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6lQViaiaazgKwu3ASkx2y57ib6ISo2VFcU2BYlssBOpcOQcjB5rSVpl36mTeQD5lzAvY9wwxyOuebVA/0, createdBy=57c11919303, createdName=wl1122050, createdTime=Thu Sep 01 06:29:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107617, encodeId=864910e61707, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107619, encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-01 李东泽

    嗯,不错,,要认真读一遍。

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 12:47:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108901, encodeId=92d510890151, content=嗯,不错,,要认真读一遍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Sep 01 13:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108647, encodeId=8b3410864eff, content=指南应该是工作的规范,但不应该成为一种束缚, beContent=null, objectType=article, channel=null, level=null, 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encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-09-01 wl1122050

    指南应该是工作的规范,但不应该成为一种束缚

    0

  7. 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encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-08-30 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!

    0

  8. 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encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-08-30 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 12:47:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108901, encodeId=92d510890151, content=嗯,不错,,要认真读一遍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Sep 01 13:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108647, encodeId=8b3410864eff, content=指南应该是工作的规范,但不应该成为一种束缚, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6lQViaiaazgKwu3ASkx2y57ib6ISo2VFcU2BYlssBOpcOQcjB5rSVpl36mTeQD5lzAvY9wwxyOuebVA/0, createdBy=57c11919303, createdName=wl1122050, createdTime=Thu Sep 01 06:29:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107617, encodeId=864910e61707, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107619, 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17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-08-30 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!

    0

  10. 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createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 18 15:17:00 CST 2016, time=2016-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125736, encodeId=8762125e369d, content=不错的知识点学到了很多, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160820/IMG57B7D87F2AA596063.jpg, createdBy=c3e01933512, createdName=1e0d5b16m97(暂无匿称), createdTime=Tue Sep 13 21:24:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=111457, encodeId=18ad11145e45, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Mon Sep 05 12:47:00 CST 2016, time=2016-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108901, encodeId=92d510890151, content=嗯,不错,,要认真读一遍。, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Thu Sep 01 13:05:00 CST 2016, time=2016-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=108647, encodeId=8b3410864eff, content=指南应该是工作的规范,但不应该成为一种束缚, beContent=null, objectType=article, channel=null, level=null, 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encodeId=a4f110e61914, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107621, encodeId=106410e621be, content=学习了,赞一个!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=ebe61630855, createdName=1dd8a7c5m95(暂无匿称), createdTime=Tue Aug 30 17:41:00 CST 2016, time=2016-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=107505, encodeId=a67110e505c7, content=指南如此之多,这是要找不到北了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Tue Aug 30 14:54:00 CST 2016, time=2016-08-30, status=1, ipAttribution=)]
    2016-08-30 李东泽

    指南如此之多,这是要找不到北了

    0

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肺癌是导致癌症死亡的最常见癌症类型,占所有肿瘤相关死亡的大约三分之一。其中腺癌(一种非小细胞肺癌)占所有诊断肺癌的大约40%,但是目前治疗这种癌症的有效方法仍然很少。 最近哈佛医学院的研究人员发现了一种人类肺腺癌的新亚型。这项研究有助于确定哪些肺癌高风险病人可能适于选用新的治疗方法来抑制疾病进展。相关研究结果发表在国际学术期刊Science Translational Medicine上。

Lancet:肺癌治疗的新靶点

尽管非小细胞肺癌(NSCLC)及小细胞肺癌(SCLC)的致病驱动基因谱不同,但越来越多的证据表明两者均有潜在的治疗靶点。携带EGFR突变或ALK重排的腺癌患者,一线靶向治疗已成共识,然而,在SCLC的靶向治疗药物大都仍未见曙光。大量的临床前期研究及临床试验进一步探讨肺癌的特性,如致癌基因,DNA损伤修复,血管生成以及肿瘤干细胞的适应性等。备受关注的免疫治疗目前也致力于研发个体化的免疫疗法。在该

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