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ADA 2016:糖尿病高危患者可通过生活方式干预延迟或预防疾病发生

2016-06-18 Seven L 译 MedSci原创

美国糖尿病协会科学年会称,对于糖尿病高危人群,生活方式干预可延迟或预防疾病的发生,并且这种影响是独立于减重的。匹兹堡大学公共卫生研究学院流行病学系教授Andrea M. Kriska博士同事对1796例参与者进行了12年的随访研究,随机分为生活方式干预组(营养及身体活动强化干预,以每周150分钟的运动时间和7%的体重下降为目标)(n = 589)、二甲双胍组(n = 599)或安慰剂组(n = 6

美国糖尿病协会科学年会称,对于糖尿病高危人群,生活方式干预可延迟或预防疾病的发生,并且这种影响是独立于减重的。

匹兹堡大学公共卫生研究学院流行病学系教授Andrea M. Kriska博士同事对1796例参与者进行了12年的随访研究,随机分为生活方式干预组(营养及身体活动强化干预,以每周150分钟的运动时间和7%的体重下降为目标)(n = 589)、二甲双胍组(n = 599)或安慰剂组(n = 605)。

数据显示,与二甲双胍或安慰剂组相比,生活方式干预组参与者的身体活动显著增加(P =0.003)。无论是哪一组的参与者,在平均11.9年的时间里,每周6个代谢当量任务时间(METs)可降低2%的糖尿病发生率。

相比基线运动时间已经达到目标的参与者,基线每周运动时间少于150分钟的参与者增加运动可以带来更多的好处(HR = 0.95;95% CI,0.93-0.97)。

研究结果表明,平均12年的身体活动可降低糖尿病患病风险,并且基线运动水平越差的参与者,通过运动获益更大。此外,糖尿病高危人群在保持体重的同时可适当增加身体活动水平,可延缓或阻止糖尿病的进展。

原始出处:


Kriska AM, et al. 379-OR. Presented at: American Diabetes Association’s Scientific Sessions; June 10-14, 2016; New Orleans.

Lifestyle intervention may delay, prevent diabetes in high-risk patients
.Healio.June 16, 2016


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  2. [GetPortalCommentsPageByObjectIdResponse(id=1955748, encodeId=4aca1955e483a, content=<a href='/topic/show?id=5b0b1022667b' target=_blank style='color:#2F92EE;'>#高危患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102266, encryptionId=5b0b1022667b, topicName=高危患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Tue Nov 22 23:32:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=132119, encodeId=52d0132119e7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:28:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125798, encodeId=7d2a125e982a, content=生活方式在疾病的发生发展中有很大的作用, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:36:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106344, encodeId=bfce1063441e, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Aug 28 15:56:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264594, encodeId=acc8126459422, content=<a href='/topic/show?id=150f19229c' target=_blank style='color:#2F92EE;'>#ADA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1922, encryptionId=150f19229c, topicName=ADA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Jun 19 15:32:00 CST 2016, time=2016-06-19, status=1, ipAttribution=)]
    2016-09-21 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1955748, encodeId=4aca1955e483a, content=<a href='/topic/show?id=5b0b1022667b' target=_blank style='color:#2F92EE;'>#高危患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102266, encryptionId=5b0b1022667b, topicName=高危患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Tue Nov 22 23:32:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=132119, encodeId=52d0132119e7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:28:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125798, encodeId=7d2a125e982a, content=生活方式在疾病的发生发展中有很大的作用, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:36:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106344, encodeId=bfce1063441e, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Aug 28 15:56:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264594, encodeId=acc8126459422, content=<a href='/topic/show?id=150f19229c' target=_blank style='color:#2F92EE;'>#ADA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1922, encryptionId=150f19229c, topicName=ADA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Jun 19 15:32:00 CST 2016, time=2016-06-19, status=1, ipAttribution=)]
    2016-09-13 舒心和人

    生活方式在疾病的发生发展中有很大的作用

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1955748, encodeId=4aca1955e483a, content=<a href='/topic/show?id=5b0b1022667b' target=_blank style='color:#2F92EE;'>#高危患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102266, encryptionId=5b0b1022667b, topicName=高危患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=05a2499, createdName=dzx0922889, createdTime=Tue Nov 22 23:32:00 CST 2016, time=2016-11-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=132119, encodeId=52d0132119e7, content=文章很好,非常有益, beContent=null, objectType=article, channel=null, level=null, likeNumber=105, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Wed Sep 21 08:28:00 CST 2016, time=2016-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=125798, encodeId=7d2a125e982a, content=生活方式在疾病的发生发展中有很大的作用, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Tue Sep 13 22:36:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=106344, encodeId=bfce1063441e, content=深度好文,值得学习,赞!, beContent=null, objectType=article, channel=null, level=null, likeNumber=111, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sun Aug 28 15:56:00 CST 2016, time=2016-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264594, encodeId=acc8126459422, content=<a href='/topic/show?id=150f19229c' target=_blank style='color:#2F92EE;'>#ADA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1922, encryptionId=150f19229c, topicName=ADA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Sun Jun 19 15:32:00 CST 2016, time=2016-06-19, status=1, ipAttribution=)]
    2016-08-28 ylzr123

    深度好文,值得学习,赞!

    0

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    2016-06-19 智智灵药

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奥克兰理工大学的Valery L. Feigin博士及同事指出,卒中的危险因素中,行为因素作用力更强。不良饮食习惯、吸烟、饮酒、缺乏锻炼等会增加民众患高血压、糖尿病、高血脂等的风险,进而增加民众患卒中的风险。不健康的生活方式是导致民众卒中的重要原因,采用健康的生活方式可预防卒中的发生。数据显示,近1/3的卒中病例是由于空气污染所致。有很多研究关注空气污染与民众患心血管疾病的风险,但尚未发现强有力的

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