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Rheumatology:双能CT与超声诊断痛风敏感性相当

2014-01-27 佚名 不详

痛风是一种典型的代谢异常性疾病,患者表现出尿酸生成过度或排泄不良,最终导致了高尿酸血症。长期高尿酸血症引起了尿酸盐晶体在关节腔及软组织中的沉积,最终导致了痛风性关节炎的发作或痛风石的产生。纵观医学史,急性痛风性关节炎的痛感,是被认知的最剧烈的疼痛之一。所以尽早诊断痛风、正确治疗痛风显得尤为重要。 为比较双能CT(DECT)与超声(US)在痛风性关节炎诊断中的差异,并分

痛风是一种典型的代谢异常性疾病,患者表现出尿酸生成过度或排泄不良,最终导致了高尿酸血症。长期高尿酸血症引起了尿酸盐晶体在关节腔及软组织中的沉积,最终导致了痛风性关节炎的发作或痛风石的产生。纵观医学史,急性痛风性关节炎的痛感,是被认知的最剧烈的疼痛之一。所以尽早诊断痛风、正确治疗痛风显得尤为重要。

为比较双能CT(DECT)与超声(US)在痛风性关节炎诊断中的差异,并分析关节腔积液检查与影像学检查结果是否存在一致性,来自奥地利维也纳医科大学的Gruber博士等进行了一项研究,发现DECT与US对痛风诊断的敏感性相当,研究发表于2014年1月的《风湿病学》杂志上。

研究共纳入21例患者(17例男性和4例女性)的37个关节,这些关节疑似为急性或慢性痛风。研究者对患者的手、腕、足、踝、膝及肘关节进行DECT扫描,使用彩色编码的痛风软件对扫描结果进行处理,同时使用US对上述关节进行检查。此外,共有14个关节接受了关节滑液抽吸术,以检测关节腔积液成分。

在37个关节中,DECT影像显示25个关节存在尿酸盐结晶沉积,而US检查的相应结果为24个。对关节腔积液的检查发现, 14个关节中有12个存在尿酸盐结晶。DECT与US的结果一致性为32/37,DECT与关节腔积液检查结果的一致性为12/14,US与关节腔积液检查结果的一致性为14/14。

研究者认为,在临床工作中,DECT与US对痛风性关节炎的诊断敏感性相当。然而,DECT的检查结果可能存在假阴性,需要临床医师进行详细评估。

原文出处:

Gruber M, Bodner G, Rath E, Supp G, Weber M, Schueller-Weidekamm C.Dual-energy computed tomography compared with ultrasound in the diagnosis of gout.Rheumatology (Oxford). 2014 Jan;53(1):173-9. doi: 10.1093/rheumatology/ket341. Epub 2013 Oct 17.

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