The Lancet：对“正常血压”进行治疗或可帮助挽救患者的生命

2015-12-28 佚名生物谷

来自牛津大学的研究者近日表示，尽管个体血压正常，但给予处于心脏病发作和中风高风险的患者降血压的药物或可挽救数百万人的生命，文章中研究者基于对过去20年超过60万人进行的123项临床试验，随后他们建议应当立即检查当前的治疗指南。相关研究刊登于The Lancet杂志上，研究人员Kazem Rahimi表示，我们发现，将个体血压降低至推荐的标准或可有效帮助降低个体患心血管疾病的发生风险，而这一举动

来自牛津大学的研究者近日表示，尽管个体血压正常，但给予处于心脏病发作和中风高风险的患者降血压的药物或可挽救数百万人的生命，文章中研究者基于对过去20年超过60万人进行的123项临床试验，随后他们建议应当立即检查当前的治疗指南。

相关研究刊登于The Lancet杂志上，研究人员Kazem Rahimi表示，我们发现，将个体血压降低至推荐的标准或可有效帮助降低个体患心血管疾病的发生风险，而这一举动也将潜在挽救数百万人的生命。据美国心脏协会数据显示，正常血压应该低于120/80。本文研究中，研究者发现，心脏收缩压每降低10mmHg就会降低个体五分之一的心脏病发作风险，四分之一的中风和心衰风险，同时还会降低个体13%的死亡风险。

研究者还补充道，更为重要的是，这些疾病风险的降低在一系列高风险患者中都是一样的，这并不取决于是否患者的血压已经够低了，比如低于130mmHg；高风险的患者包括有心脏或动脉疾病的历史、中风、糖尿病或心衰患者等；高血压是引发心脏疾病和中风的主要原因，其在全球影响着超过10亿人的健康，而且每年会引发940万人死亡。

目前降低持续的高血压的益处已经被阐明，但研究者具体并不清楚是否正常血压的个体会因这种降血压疗法而获益，来自谢菲尔德大学的研究者Tim Chico就强调说，正常血压的个体因这种疗法是否获益取决于个体是否存在其它机体风险因素。比如如果某人已经处于低风险了，而降低20%的风险似乎并不是那么重要；然而如果个体处于高风险，那么20%风险的降低或许会帮助挽救很多患者的生命。

原始出处：

Treat 'normal' blood pressure to save lives, study urges.MedicalXpress.Dec 24,2015

Dena Ettehad,Connor A Emdin,et al.Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis.The Lancet.Dec 23,2015

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2016-01-10 howi

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2016-02-11 lietome1

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值得关注！

130 0
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2016-01-09 medsic

继续分享！

92 0
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2016-01-09 medsic

嗯，

120 0
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2016-01-09 medsic

不错！

142 0
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2016-01-09 medsic

好文章，

178 0
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2015-12-30 惜言

好！

148 0
[GetPortalCommentsPageByObjectIdResponse(id=1828372, encodeId=c34318283e2d7, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sun Jan 10 06:12:00 CST 2016, time=2016-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63958, encodeId=0a9363958e0, content=收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=841a1636000, createdName=lietome1, createdTime=Thu Feb 11 09:51:00 CST 2016, time=2016-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=63957, encodeId=232f6395ede, content=赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=166, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=841a1636000, createdName=lietome1, createdTime=Thu Feb 11 09:51:00 CST 2016, time=2016-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55031, encodeId=3d4555031a8, content=值得关注！, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32ba1611217, createdName=medsic, createdTime=Sat Jan 09 21:27:00 CST 2016, time=2016-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55030, encodeId=1cb555030f3, content=继续分享！, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32ba1611217, createdName=medsic, createdTime=Sat Jan 09 21:27:00 CST 2016, time=2016-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55029, encodeId=394b55029c5, content=嗯，, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32ba1611217, createdName=medsic, createdTime=Sat Jan 09 21:27:00 CST 2016, time=2016-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55028, encodeId=4fe5550286a, content=不错！, beContent=null, objectType=article, channel=null, level=null, likeNumber=142, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32ba1611217, createdName=medsic, createdTime=Sat Jan 09 21:27:00 CST 2016, time=2016-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55027, encodeId=8f725502e15, content=好文章，, beContent=null, objectType=article, channel=null, level=null, likeNumber=178, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32ba1611217, createdName=medsic, createdTime=Sat Jan 09 21:27:00 CST 2016, time=2016-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50662, encodeId=f06d506624e, content=好！, beContent=null, objectType=article, channel=null, level=null, likeNumber=148, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20150830/IMG55E294026A9942981.jpg, createdBy=fa351627501, createdName=惜言, createdTime=Wed Dec 30 23:58:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50137, encodeId=f5625013e0c, content=不明白, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2d331664955, createdName=老段, createdTime=Tue Dec 29 12:21:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
2015-12-29 老段

不明白

79 0

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