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非比较研究及前后对照研究(单臂研究)结局变量Meta分析的效应量选择

2013-11-30 沈旭慧 王珍 MedSci原创

关于成组设计类型比较研究的Meta分析或系统评价理论与方法学日趋成熟,但对单变量关系,又称非比较性研究或单组研究结局变量以及两变量关系研究,比如 前后比较研究变量进行综合分析的文献与方法则相对较少。目的:探讨针对单变量关系研究集中趋势描述的常用统计量比例或率及均数以及两变量关系研究中前后比 较研究的常用统计量均数得分法的Meta分析法。方法:应用计算机检索中文CNKI全文数据库、维普全文数据库

关于成组设计类型比较研究的Meta分析或系统评价理论与方法学日趋成熟,但对单变量关系,又称非比较性研究或单组研究结局变量以及两变量关系研究,比如 前后比较研究变量进行综合分析的文献与方法则相对较少。目的:探讨针对单变量关系研究集中趋势描述的常用统计量比例或率及均数以及两变量关系研究中前后比 较研究的常用统计量均数得分法的Meta分析法。方法:应用计算机检索中文CNKI全文数据库、维普全文数据库、万方中国博硕数据库、PubMed数据库 中非比较性研究以及前后比较研究相关的Meta分析或系统评价方法学文献。结果与结论:单变量集中趋势描述的几种常见统计量有均数、中位数、众数或比例, 但Meta分析最常见的是比例和均数f算术平均数)。实验前后比较研究,从根本上来讲也属于对同一反应人群(单样本)同一变量的测量值的集中趋势研究,与 上述讨论的稍有不同之处在于该研究形式是针对同一变量的同一反应人群在两个不同时点测量值集中趋势的比较研究。这种类型的研究在统计学上也称作配对设计的 均数比较,针对此类型的研究,有两种效应量指标可以选择,一种是未标化的平均得分,另一种是标化的平均得分。如果纳入Meta分析的

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  1. [GetPortalCommentsPageByObjectIdResponse(id=62786, encodeId=416362e8607, content=感觉有点麻烦, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aba81626422, createdName=Kiste, createdTime=Tue Feb 02 13:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=13210, encodeId=8e131321012, content=非常实用,谢谢1, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f605106987, createdName=keoufang, createdTime=Thu Dec 18 20:22:00 CST 2014, time=2014-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775259, encodeId=b94d1e752598c, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Sun Nov 09 06:25:00 CST 2014, time=2014-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895697, encodeId=987f189569e5b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Jul 10 05:25:00 CST 2014, time=2014-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887371, encodeId=d3c9188e371e2, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu Nov 13 03:25:00 CST 2014, time=2014-11-13, status=1, ipAttribution=)]
    2016-02-02 Kiste

    感觉有点麻烦

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=62786, encodeId=416362e8607, content=感觉有点麻烦, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aba81626422, createdName=Kiste, createdTime=Tue Feb 02 13:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=13210, encodeId=8e131321012, content=非常实用,谢谢1, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f605106987, createdName=keoufang, createdTime=Thu Dec 18 20:22:00 CST 2014, time=2014-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775259, encodeId=b94d1e752598c, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Sun Nov 09 06:25:00 CST 2014, time=2014-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895697, encodeId=987f189569e5b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Jul 10 05:25:00 CST 2014, time=2014-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887371, encodeId=d3c9188e371e2, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu Nov 13 03:25:00 CST 2014, time=2014-11-13, status=1, ipAttribution=)]
    2014-12-18 keoufang

    非常实用,谢谢1

    0

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    2014-11-09 amyloid
  4. [GetPortalCommentsPageByObjectIdResponse(id=62786, encodeId=416362e8607, content=感觉有点麻烦, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aba81626422, createdName=Kiste, createdTime=Tue Feb 02 13:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=13210, encodeId=8e131321012, content=非常实用,谢谢1, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f605106987, createdName=keoufang, createdTime=Thu Dec 18 20:22:00 CST 2014, time=2014-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775259, encodeId=b94d1e752598c, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Sun Nov 09 06:25:00 CST 2014, time=2014-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895697, encodeId=987f189569e5b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Jul 10 05:25:00 CST 2014, time=2014-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887371, encodeId=d3c9188e371e2, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu Nov 13 03:25:00 CST 2014, time=2014-11-13, status=1, ipAttribution=)]
    2014-07-10 一闲
  5. [GetPortalCommentsPageByObjectIdResponse(id=62786, encodeId=416362e8607, content=感觉有点麻烦, beContent=null, objectType=article, channel=null, level=null, likeNumber=130, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aba81626422, createdName=Kiste, createdTime=Tue Feb 02 13:02:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=13210, encodeId=8e131321012, content=非常实用,谢谢1, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f605106987, createdName=keoufang, createdTime=Thu Dec 18 20:22:00 CST 2014, time=2014-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1775259, encodeId=b94d1e752598c, content=<a href='/topic/show?id=937d46650bf' target=_blank style='color:#2F92EE;'>#对照#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46650, encryptionId=937d46650bf, topicName=对照)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8ae138776909, createdName=amyloid, createdTime=Sun Nov 09 06:25:00 CST 2014, time=2014-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895697, encodeId=987f189569e5b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Thu Jul 10 05:25:00 CST 2014, time=2014-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887371, encodeId=d3c9188e371e2, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Thu Nov 13 03:25:00 CST 2014, time=2014-11-13, status=1, ipAttribution=)]
    2014-11-13 guojianrong
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