Baidu
map

Sci Transl Med:医院不是感染的源头,自身携带细菌更危险

2017-05-26 文姜 生物探索

医院可能看起来很干净,但微生物学家更清楚地知道:金黄色葡萄球菌遍布医生的寻呼机,纹带棒状杆菌生活在水槽和水龙头,粪肠球菌在床栏上威胁所有患者的健康。不过Science Translational Medicine上5月24日新刊登的一篇文章表明:最危险的细菌不是你在医院里遇到的,而是你自身携带的。科学家们评论已经有人怀疑在医院感染的病原体可能是来自患者本身,但这是第一个环境核查的研究。Scienc

医院可能看起来很干净,但微生物学家更清楚地知道:金黄色葡萄球菌遍布医生的寻呼机,纹带棒状杆菌生活在水槽和水龙头,粪肠球菌在床栏上威胁所有患者的健康。不过Science Translational Medicine上5月24日新刊登的一篇文章表明:最危险的细菌不是你在医院里遇到的,而是你自身携带的。科学家们评论已经有人怀疑在医院感染的病原体可能是来自患者本身,但这是第一个环境核查的研究。Science新闻同一日对此进行了报道。

医院遍布了致病微生物

如果你不知道微生物的源头在哪里,跟踪是它们困难的。因此,在这项新的研究中,由芝加哥大学的微生物生态学家Jack Gilbert团队将调查了一所全新的医院:该大学的护理中心,此中心于2013开业。在开张的几个月前,研究人员向建筑师咨询,并向10层的医生和护士广泛地调研,在地图上标出了工作人员和患者会进出的地方,他们会使用的洗手间和自动售货机,因为这些地方患者可能会接触到其他人。在医院开张前,他们擦拭消毒了所有表面,使其是一个干净的环境。

但这没有持续很长时间。第一天运行期间,在手机、台面、在护士台的电脑鼠标上棒状杆菌、金黄色葡萄球菌和链球菌的数量急剧上升。这些细菌是感染白喉、耐青霉素金黄色葡萄球菌病、肺炎疾病的病源,对免疫系统减弱的人特别危险。

在研究结果中,研究人员发现病床床栏是细菌的一个重要的据点:这里的微生物和发现在患者身上的很相似,多于任何其他地方的采样。这表明床栏能窝藏起前一个患者的细菌到病床的下一任,除非中间消毒。

但带来获得性感染的细菌不来自医院

在接下来的365天,Gilbert和他的同事们在许多房间表面以及医生、护士、医院工作人员和患者皮肤和衣服上取了共6523例样。研究小组比较了患者到达和出院时的微生物状况,并应用统计学方法确定了患者在住院期间对微生物构成的影响。

Science Translational Medicine上的文章报道了研究结果:参与这项研究的252名患者中,大约有20的人被专家定义为医院获得性感染。这是接近疾病控制和预防中心的统计数据的——25位住院病人中大约有一个会感染这种疾病。但是,根据该研究小组的分析,新研究中对病人房间,以及他们与之互动的护士和医生身上的采样,都未能发现能对他们的感染负责的细菌,这表明他们似乎没有从医院获得微生物。Gilbert说:“最有可能的解释是病人入院时已经感染了这些细菌。”

在医疗界,大都认为医院是潜在的危险疾病的港口,这对目前的思维是一个很大的转变。研究表明医院房间的微生物可能不会比病人家里的微生物更危险。Gilbert 说:“对于我们如何看待医院获得性感染,将是一个范式的转变。”

他认为几乎不可能完全消毒任何房间,而且大多数医院已经做好了尽可能没问题的护理工作。他说,与其集中精力进行更有效的消毒工作,不如在可能的情况下花更多的资源对患者进入医院之前进行益生菌和抗生素治疗。

原始出处:

Simon Lax,et al. Bacterial colonization and succession in a newly opened hospital. Science Translational Medicine.  2017 May.

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1656790, encodeId=7df41656e90cd, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Nov 14 10:07:00 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067229, encodeId=a933206e22955, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 23 13:07:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203614, encodeId=8b12203614a4, content=新观念,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sun May 28 15:35:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203394, encodeId=a10120339439, content=真的是新观念,入院前患者自身微生物的检查。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun May 28 00:36:43 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607571, encodeId=5add160e5711b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun May 28 00:07:00 CST 2017, time=2017-05-28, status=1, ipAttribution=)]
    2017-11-14 bsmagic9140
  2. [GetPortalCommentsPageByObjectIdResponse(id=1656790, encodeId=7df41656e90cd, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Nov 14 10:07:00 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067229, encodeId=a933206e22955, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 23 13:07:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203614, encodeId=8b12203614a4, content=新观念,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sun May 28 15:35:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203394, encodeId=a10120339439, content=真的是新观念,入院前患者自身微生物的检查。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun May 28 00:36:43 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607571, encodeId=5add160e5711b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun May 28 00:07:00 CST 2017, time=2017-05-28, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1656790, encodeId=7df41656e90cd, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Nov 14 10:07:00 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067229, encodeId=a933206e22955, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 23 13:07:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203614, encodeId=8b12203614a4, content=新观念,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sun May 28 15:35:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203394, encodeId=a10120339439, content=真的是新观念,入院前患者自身微生物的检查。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun May 28 00:36:43 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607571, encodeId=5add160e5711b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun May 28 00:07:00 CST 2017, time=2017-05-28, status=1, ipAttribution=)]
    2017-05-28 I come

    新观念,好文章

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1656790, encodeId=7df41656e90cd, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Nov 14 10:07:00 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067229, encodeId=a933206e22955, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 23 13:07:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203614, encodeId=8b12203614a4, content=新观念,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sun May 28 15:35:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203394, encodeId=a10120339439, content=真的是新观念,入院前患者自身微生物的检查。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun May 28 00:36:43 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607571, encodeId=5add160e5711b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun May 28 00:07:00 CST 2017, time=2017-05-28, status=1, ipAttribution=)]
    2017-05-28 惠映实验室

    真的是新观念,入院前患者自身微生物的检查。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1656790, encodeId=7df41656e90cd, content=<a href='/topic/show?id=3ca31e71903' target=_blank style='color:#2F92EE;'>#TRA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17719, encryptionId=3ca31e71903, topicName=TRA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=757b24868428, createdName=bsmagic9140, createdTime=Tue Nov 14 10:07:00 CST 2017, time=2017-11-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2067229, encodeId=a933206e22955, content=<a href='/topic/show?id=d0841e75535' target=_blank style='color:#2F92EE;'>#Transl#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17755, encryptionId=d0841e75535, topicName=Transl)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 23 13:07:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203614, encodeId=8b12203614a4, content=新观念,好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK9CDibOwszLoEBg36ZXqzB5NDasNV9GTfFDmBicM1V8hUS4OtTicG3IiaFIKq4wqD23LUxORRJXqjVs/0, createdBy=00e81647535, createdName=I come, createdTime=Sun May 28 15:35:00 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203394, encodeId=a10120339439, content=真的是新观念,入院前患者自身微生物的检查。, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun May 28 00:36:43 CST 2017, time=2017-05-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1607571, encodeId=5add160e5711b, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun May 28 00:07:00 CST 2017, time=2017-05-28, status=1, ipAttribution=)]

相关资讯

Clin Microbiol Infec:警惕:出现一些症状后即使尿检阴性也可能是膀胱炎!

大多数女性在排尿时疼痛,或需要小便或尿急,可能会有细菌感染,即使尿液检测不到任何症状。

J Periodontol:种植体与天然牙龈沟液中生物标志物及细菌种类在同一个体中仍有差异

本研究旨在通过横断面研究收集接受种植修复患者其健康及种植体周围炎位点的龈沟液来评估其种植体龈沟液(PICF)/龈沟液(GCF)中细胞因子的水平。 研究共纳入了15名无系统性疾病的研究对象,共包括97颗种植体/牙齿(58颗种植体:19颗健康,20颗种植体周围黏膜炎,19颗种植体周围炎;39颗天然牙:19颗健康,12颗牙龈炎,8颗牙周炎),收取PICF/GCF进行免疫检测,实时定量PCR分析。收

Sci Rep:治疗细菌性骨感染的新物质!

由多种细菌引起的骨感染是一种严重的并发症,它们对经典抗生素具有一定的抗药性,且有生物膜形成,难以根除。抗菌肽(AMP)是天然存在的肽类,是治疗关节感染的具有潜力的物质。近期,一项发表在杂志Sci Rep上的研究旨在分析源自优化文库的短人工肽的作用:(1)对不同细菌种类的抗菌作用的影响,(2)对生物膜的功效,(3)对成骨细胞样细胞的影响。此项研究选用大肠杆菌、粪肠球菌、铜绿假单胞菌、金黄色葡萄球菌(

Nat Med:经常被病菌感染导致记忆下降

纽约大学Langone医学中心的研究人员5月15日在线发表《Nature Medicine》文章,声称发现了机体对抗流感病毒和HIV病毒的免疫反应导致学习和记忆问题的分子机理。文中证据表明,病毒进入小鼠血液后,开启“急救”免疫细胞(CX3CR1highLY6Clow单核细胞)释放炎症信号蛋白TNFα,TNFα运行至大脑,阻止神经细胞连接形成。病毒之所以这么做,目的是阻止神经细胞将免疫反应感觉信息转

科学家如何“以毒攻毒”治疗多种人类疾病?

在开发治疗多种人类疾病新型疗法的道路上,有这么一种奇特的方法,那就是以毒攻毒,当然科学家们也非常擅长使用这种方法来帮助改善/治疗患者的疾病,比如就有来自里约热内卢的科学家们用一种称作沃巴克氏菌的细菌来感染蚊子,这种细菌能够对携带登革病毒的埃及伊蚊起到防疫作用,防止病毒在其体内扩散,从而就成功实现了利用蚊子来对付登革热的目的;当然也有研究人员利用蜗牛毒液来开发速效胰岛素用于治疗糖尿病。

Nature、Cell两篇文章发现10种用于疾病诊断的CRISPR酶

最近来自加利福尼亚大学的研究人员通过研究描述了10种新型的CRISPR酶,这些酶一旦被激活其行为就像“吃豆人”一样能够“嚼碎”RNA,因此这些酶类或许能作为诊断传染性病毒的敏感检测器。这种新型的酶类是CRISPR蛋白—Cas13a的突变体,

Baidu
map
Baidu
map
Baidu
map