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ACC 2016:冠心病患者风险、治疗、预后的性别差异

2016-03-25 Seven L 译 MedSci原创

在芝加哥举行的第65届美国心脏病学会科学会议称,冠状动脉性疾病(CAD)的风险因素存在性别差异,需要针对性别特异性进行合适的CAD风险评估。研究成果发表在近期的JACC: Cardiovascular Imaging。Kshipra Hemal对10003名症状可疑稳定型CAD的参与者进行了研究,结果显示,女性与男性相比,心脏风险因素数量更多,但危险度更低。此外抑郁、久坐及早发心血管病家族史等危险

在芝加哥举行的第65届美国心脏病学会科学会议指出,冠心病(CAD)的风险因素存在性别差异,需要针对性别特异性进行合适的CAD风险评估。研究成果发表在近期的JACC: Cardiovascular Imaging

Kshipra Hemal对10003名症状可疑稳定型CAD的参与者进行了研究,结果显示,女性与男性相比,心脏风险因素数量更多,但危险度更低。此外抑郁、久坐及早发心血管病家族史等危险因素更多见于女性,但是大多数风险评估问卷调查排除了这些危险因素。不过无论男女,可疑心血管疾病时最常见的症状都是胸痛和呼吸短促。

Hemal说:“结果表明,我们应该充分考虑心脏病诊断过程中的性别差异,接下来我们将会探究性别差异对患者预后的影响。”

与此同时,C. Noel Bairey Merz等人发现,很多女性知道与心血管疾病相关的危险因素,但是不晓得如何处理风险因素。

他们对1011名25-60岁的美国女性进行了一项研究,结果显示,74%的有至少1个危险因素,但是只有16%的被告知了风险。另外,76%的参与者很少或几乎不与亲属朋友讨论心血管健康问题。此外,有34%的女性被告知需要减肥,45%的认为如果不能减肥,那么就不会进行健康讨论。

不仅如此,治疗和预后也存在性别差异。Edina Cenko对6679名STEMI患者进行了一项研究,患者在首发症状出现后24小时内行首次PCI治疗。研究显示,住院后首次PCI时间延迟2小时以上在女性患者中更常见,短期死亡率也是女性高于男性患者。

还有Mostafa El-Refai对193名(女性占21%)STEMI患者的研究显示,DTB时间也存在性别差异,女性相比男性,DTB时间显著延迟。而这些延迟与临床及系统因素都有关,女性患者更容易遭受治疗推迟。

原始出处:

Study Finds Sex-Specific Approaches Needed For CAD Evaluation
Separate Studies Find Women Experience Differences in Advice, Treatment and Outcomes.
Mar 23,2016


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    2016-03-26 田田7760

    要好好学习,趋利避害

    0

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    2016-03-26 milkshark

    的确这样

    0

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    2016-03-26 milkshark

    推荐好好学习

    0

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