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Chest:过量饮酒又一危害——影响呼吸

2016-08-03 fsy 译 MedSci原创

来自芝加哥洛约拉大学医学院的研究人员领导的一项研究发现,过量饮酒存在潜在的新的健康问题。研究发现过度饮酒的成年人与不饮酒的成年人相比,会呼出较少的一氧化氮。该成果发表在Chest杂志上,由于一氧化氮有助于预防某些有害细菌,从而该研究变得显著。“酒精似乎会破坏肺部的健康平衡,”该研究的作者,医学博士Majid Afshar说。Afshar博士是洛约拉医学院胸腔科医师,是芝加哥洛约拉大学斯特里奇学校的

来自芝加哥洛约拉大学医学院的研究人员领导的一项研究发现,过量饮酒存在潜在的新的健康问题。

研究发现过度饮酒的成年人与不饮酒的成年人相比,会呼出较少的一氧化氮。该成果发表在Chest杂志上,由于一氧化氮有助于预防某些有害细菌,从而该研究变得显著。

“酒精似乎会破坏肺部的健康平衡,”该研究的作者,医学博士Majid Afshar说。Afshar博士是洛约拉医学院胸腔科医师,是芝加哥洛约拉大学斯特里奇学校的公共健康科学的肺部和重症监护医学的助理教授。

这是第一次报告过量饮酒和一氧化氮之间联系的研究。

Afshar博士是洛约拉酒精研究计划中50名研究人员中的一名,他们正在探索酒精对多个器官系统的影响。他们正在研究急性、暴饮和慢性饮酒时分子、细胞和生理反应。该研究的重点主要集中在内分泌、胃肠道、免疫、神经和骨骼系统。

Afshar博士及其同事分析了来自美国疾病控制中心和预防与全国健康和调查(NHANES)的数据。NHANES进行了面试和体检来评估美国人的健康和营养状况。

洛约拉研究人员分析了在NHANES研究中,2007年和2012年期间12,059名成年人的数据。过度饮酒者被定义为大量饮酒者(对于女性来说平均每天超过一杯,对于男性来说平均每天超过两杯)和每月至少暴饮一次的饮酒者(对于女性每次4杯或更多,对于男性每次5杯或更多)。

在检查的样本人群中,26.9%的参与者过度饮酒。对哮喘、吸烟、饮食、人口统计学和其他因素进行控制后,研究人员发现,过量饮酒者呼出一氧化氮水平比从不饮酒的成人低,而且饮酒量越大,一氧化氮水平越低。

一氧化氮是在呼吸过程中由身体产生的一种无色气体。一氧化氮分子含有一个氮原子和一个氧原子的。一氧化氮和类似分子在杀死引起呼吸道感染的细菌过程中起重要作用。

在一名哮喘患者中,通过呼气测试中呼出的一氧化氮量可以知道患者的药物是如何工作的。过量饮酒可能会使这样的测试结果复杂化。“肺部医生可能需要考虑到这一点,”Afshar说。

Afshar博士及其同事得出结论:“考虑到饮酒对于呼出一氧化氮水平的影响,呼出一氧化氮水平应该是一个额外的考虑因素,探索呼吸道中酒精和一氧化氮之间复杂的相互作用的进一步的调查是很有必要的。”

原始出处:

Majid Afshar, Jill A. Poole, Guichan Cao,et al.Exhaled Nitric Oxide Levels Among Adults With Excessive Alcohol Consumption. Chest, 2016.8.3

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    2017-03-08 Smile2680
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    2016-09-18 1e10c84am36(暂无匿称)

    不错哦继续关注

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