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颅脑损伤合并糖尿病性胃轻瘫1例

2018-03-15 佚名 中国临床神经外科杂志

男,42岁,因交通事故致头部外伤后头痛、头昏5h入院。

【一般资料】

男,42岁

【主诉】

因交通事故致头部外伤后头痛、头昏5h入院。

【既往史】

既往有糖尿病史10余年。

【体格检查】

神志清楚,GCS评分15分,双侧瞳孔等大等圆,直径2.5mm,对光反射灵敏;四肢肌力5级,肌张力正常。

【辅助检查】

入院后头颅CT示左侧额叶挫伤性小血肿,左侧额部硬膜下薄层血肿,蛛网膜下腔出血,左侧顶骨骨折。

【治疗】

入院后予保守治疗,予脱水、止血、神经营养药物应用等处理。病人伤后有头痛、恶心、呕吐,予肌肉注射胃复安对症处理,恶心、呕吐等症状缓解。10d后,病人头痛等症状渐好转,两周后复查CT示颅内出血基本吸收。伤后18d左右,病人又出现恶心、呕吐频繁,当时考虑颅内压增高,予静脉滴注小剂量甘露醇、肌肉注射胃复安等处理,但疗效欠佳。腰椎穿刺术测压为125mmH2O。肝肾功能基本正常,血糖13.76mmol/L,血钠136.3mmol/L,血钾5.1mmol/L,血氯98.6mmol/L。请内分泌科会诊,考虑合并糖尿病性胃轻瘫,予停用脱水剂,应用胰岛素控制血糖,加用莫沙比利促进肠胃运动,少食多餐,病人恶心、呕吐等症状消失,病情好转出院。

【讨论】

恶心、呕吐是神经外科常见症状,常与下列因素有关:颅内压增高,表现为头痛、呕吐、视乳头水肿,应用甘露醇可缓解症状;电解质紊乱,如低钠、低氯,也可表现为腹胀、恶心、呕吐,需补充氯化钠或氯化钾;颅后窝病变,可表现为眩晕、恶心、呕吐等。对于颅脑损伤病人,颅内血肿及脑水肿可使颅内压增高,随着病情缓解,一般1周后脑水肿渐消退,颅内压渐趋下降。本文病人伤后两周又出现恶心、呕吐等症状,无明显头痛,结合CT影像及腰椎穿刺术测压结果,脑水肿已消退,不考虑颅内压增高。因病人有10余年糖尿病史,平时血糖控制不甚理想,故需考虑其他原因导致的恶心、呕吐症状。糖尿病性胃轻瘫是糖尿病常见的并发症之一。目前,其发病机制仍不十分清楚。糖尿病易引起植物神经功能紊乱,造成胃张力减弱,运动减慢,从而引起胃排空延缓,胃潴留。临床表现为腹胀、厌食、恶心、呕吐、体重减轻等,体检可见胃区胀满,有时可闻及振水音。治疗上,主要需控制血糖,应积极使病人血糖控制在理想水平,可部分改善糖尿病性胃轻瘫的胃排空延迟。饮食上,需少量多餐,低脂饮食能减轻病人胃轻瘫的症状。其他如定时使用胃动力药物,如胃复安、吗丁啉、莫沙比利等,应在餐前半小时左右服药,使其血药浓度在进餐时已达高峰。针灸治疗也有一定疗效。本文病人在治疗过程中存在一定困惑,因此,对于病人在病程中出现的症状与当前病情不符,需进一步拓宽思路,明确病因,以免延误诊治。

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    2018-03-18 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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    2018-03-17 121832a9m88暂无昵称

    学习了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=297219, encodeId=828e29e219f2, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun Mar 18 00:12:04 CST 2018, time=2018-03-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296997, encodeId=396f29699ecf, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a8f22260741, createdName=121832a9m88暂无昵称, createdTime=Sat Mar 17 06:41:33 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379957, encodeId=b9bd13e995746, content=<a href='/topic/show?id=5f3c10046499' target=_blank style='color:#2F92EE;'>#颅脑损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=86, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100464, encryptionId=5f3c10046499, topicName=颅脑损伤)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2bcd469, createdName=fengting3, createdTime=Sat Mar 17 05:57:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1397498, encodeId=0eb7139e4985d, content=<a href='/topic/show?id=8bee565436d' target=_blank style='color:#2F92EE;'>#损伤#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56543, encryptionId=8bee565436d, topicName=损伤)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eoNX3lUOlDKGBUEPNwZx0nibmdcFyeibnX4WMhUSCU2REpGRWtSmnT2CCs0dA5waxvJknYDxwtYnIcQ/132, createdBy=294e2500218, createdName=ms3046638856685384, createdTime=Sat Mar 17 05:57:00 CST 2018, time=2018-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296783, encodeId=ebab296e8314, content=学习了很多先进的医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161027/IMG58114E1818EA51495.jpg, createdBy=4b2c1959822, createdName=雅文博武, createdTime=Fri Mar 16 12:11:14 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296743, encodeId=211d296e43a2, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Fri Mar 16 09:26:11 CST 2018, time=2018-03-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296670, encodeId=1cb72966e017, content=学习学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Fri Mar 16 06:55:15 CST 2018, time=2018-03-16, status=1, ipAttribution=)]
    2018-03-16 雅文博武

    学习了很多先进的医学知识

    0

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    2018-03-16 yfjms

    学习

    0

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    2018-03-16 易水河

    学习学习了

    0

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