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Eur Urol:间质性膀胱炎/膀胱痛综合征患者Hunner病变的经尿道凝固术和经尿道切除术效果比较

2020-02-02 AlexYang MedSci原创

间质性膀胱炎/膀胱疼痛综合征(IC/BPS)是一种慢性疾病,具有与膀胱相关的慢性盆腔疼痛特征,且无有效的治疗选择。最近,有研究人员评估了经尿道切除(TUR)和经尿道凝固(TUC)在IC/BPS的Hunner病变(HL)治疗中的疗效和安全性情况。研究是一个单中心、前瞻性和随机对照的试验,包括了126名具有HL的IC/BPS患者。研究发现,两个治疗组之间的无复发时间没有差异,TUR组为12.2个月(9

间质性膀胱炎/膀胱疼痛综合征(IC/BPS)是一种慢性疾病,具有与膀胱相关的慢性盆腔疼痛特征,且无有效的治疗选择。

最近,有研究人员评估了经尿道切除(TUR)和经尿道凝固(TUC)在IC/BPS的Hunner病变(HL)治疗中的疗效和安全性情况。研究是一个单中心、前瞻性和随机对照的试验,包括了126名具有HL的IC/BPS患者。研究发现,两个治疗组之间的无复发时间没有差异,TUR组为12.2个月(95%CI,11.1-17.6个月),TUC组为11.5个月(95% CI, 9.03-16.1; p=0.735)。在治疗的12个月期间,研究人员在平均日间频率减少、夜尿、紧急事件、ICSI、ICPI、PUF症状量表和疼痛VAS方面也没有发现显著的差。不考虑治疗的类型情况下,与基线点相比,所有症状调查问卷和疼痛均具有显著的改善(p<0.05)。另外,治疗的类型(TUR或者TUC)、年龄、性别、既往水胀史和HLs数目均不影响复发。膀胱损伤的发生率在TUR组(7.9%)中要比TUC组(3.4%)更高。

最后,研究人员指出,TUC和TUR治疗HL在无复发时间和泌尿症状以及疼痛方面没有差异。但考虑到相关的并发症,医生应该选择患者最熟悉和舒适的治疗方法。

原始出处:


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    2020-06-21 lifestar
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    2020-02-02 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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