Baidu
map

Am J Clin Nutr:黄酮类食物并不能降低冠心病事件的发生

2016-10-30 MedSci MedSci原创

背景:黄酮类化合物是具有多种提出有益的心血管的膳食多酚类化合物,但在地理和种族多元化的美国,黄酮的摄入量与冠心病事件相关性(CHD)前瞻性研究较少。目的:用新的,扩大农业部黄酮类数据库,研究者评估不同地区的人群总黄酮和黄酮类的摄入量与CHD的发生的相关性,以及年龄、性别、种族、居住地区的修饰效应。设计:纳入REGARDS研究的受试者为16678名黑人和白人男性和女性,这是一项全国性的前瞻性队列研究

背景:黄酮类化合物是具有多种提出有益的心血管的膳食多酚类化合物,但在地理和种族多元化的美国,黄酮的摄入量与冠心病事件相关性(CHD)前瞻性研究较少。

目的:用新的,扩大农业部黄酮类数据库,研究者评估不同地区的人群总黄酮和黄酮类的摄入量与CHD的发生的相关性,以及年龄、性别、种族、居住地区的修饰效应。

设计:纳入REGARDS研究的受试者为16678名黑人和白人男性和女性,这是一项全国性的前瞻性队列研究。基线所有受试者均无冠心病,并全部完成block98食物频率问卷。美国农业部的黄酮类数据库评估黄酮类的摄入量,数据库最近进行了改进,解决熟食食品的遗失值,并调整加工过程中,黄酮类化合物的丢失。受试者自己报告CHD事件的发生,由专家确认。
采用Cox比例风险回归分析黄酮类检测作为冠心病的预测因素的HRs值。用中位数表示趋势。

结果:随访的平均值± SD为:6.0 ± 1.9年,共有589例发生了冠心病事件。
黄酮类化合物的摄入量与白人种族,运动,不吸烟,更多的教育和更高的收入相关。校正社会人口、健康行为和饮食因素,在模型中,花青素和原花青素的摄入量与冠心病事件发生呈负相关性(花青素最高五分位数与最低五分位数相比:HR 0.71年;95%CI:0.52,0.98;;原花青素:0.63;95%CI:0.47,0.84;)。总黄酮或其他黄酮类化合物的摄入量和冠心病事件没有相关性。

结论:花青素和原花青素的摄入量与冠心病的发病呈负相关。年龄,性别,种族,或居住地区没有显著的修饰效应。

原始出处:

Goetz ME, Judd SE, et al. Dietary flavonoid intake and incident coronary heart disease: the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. Am J Clin Nutr. 2016 Sep 21.


版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1683567, encodeId=ee68168356e7b, content=<a href='/topic/show?id=3f17103210ed' target=_blank style='color:#2F92EE;'>#黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103210, encryptionId=3f17103210ed, topicName=黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=443c27982006, createdName=fengyi821, createdTime=Thu Mar 30 10:22:00 CST 2017, time=2017-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822530, encodeId=318418225309b, content=<a href='/topic/show?id=ae0e103215ab' target=_blank style='color:#2F92EE;'>#黄酮类食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103215, encryptionId=ae0e103215ab, topicName=黄酮类食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Fri Dec 16 13:22:00 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154810, encodeId=c3c915481059, content=哎呀,观念大转, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ff901728138, createdName=1dedfe95m66(暂无匿称), createdTime=Thu Nov 10 15:24:03 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416740, encodeId=3dfd1416e40f8, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Tue Nov 01 01:22:00 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2017-03-30 fengyi821
  2. [GetPortalCommentsPageByObjectIdResponse(id=1683567, encodeId=ee68168356e7b, content=<a href='/topic/show?id=3f17103210ed' target=_blank style='color:#2F92EE;'>#黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103210, encryptionId=3f17103210ed, topicName=黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=443c27982006, createdName=fengyi821, createdTime=Thu Mar 30 10:22:00 CST 2017, time=2017-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822530, encodeId=318418225309b, content=<a href='/topic/show?id=ae0e103215ab' target=_blank style='color:#2F92EE;'>#黄酮类食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103215, encryptionId=ae0e103215ab, topicName=黄酮类食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Fri Dec 16 13:22:00 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154810, encodeId=c3c915481059, content=哎呀,观念大转, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ff901728138, createdName=1dedfe95m66(暂无匿称), createdTime=Thu Nov 10 15:24:03 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416740, encodeId=3dfd1416e40f8, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Tue Nov 01 01:22:00 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1683567, encodeId=ee68168356e7b, content=<a href='/topic/show?id=3f17103210ed' target=_blank style='color:#2F92EE;'>#黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103210, encryptionId=3f17103210ed, topicName=黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=443c27982006, createdName=fengyi821, createdTime=Thu Mar 30 10:22:00 CST 2017, time=2017-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822530, encodeId=318418225309b, content=<a href='/topic/show?id=ae0e103215ab' target=_blank style='color:#2F92EE;'>#黄酮类食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103215, encryptionId=ae0e103215ab, topicName=黄酮类食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Fri Dec 16 13:22:00 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154810, encodeId=c3c915481059, content=哎呀,观念大转, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ff901728138, createdName=1dedfe95m66(暂无匿称), createdTime=Thu Nov 10 15:24:03 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416740, encodeId=3dfd1416e40f8, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Tue Nov 01 01:22:00 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-10 1dedfe95m66(暂无匿称)

    哎呀,观念大转

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1683567, encodeId=ee68168356e7b, content=<a href='/topic/show?id=3f17103210ed' target=_blank style='color:#2F92EE;'>#黄酮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103210, encryptionId=3f17103210ed, topicName=黄酮)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=443c27982006, createdName=fengyi821, createdTime=Thu Mar 30 10:22:00 CST 2017, time=2017-03-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1822530, encodeId=318418225309b, content=<a href='/topic/show?id=ae0e103215ab' target=_blank style='color:#2F92EE;'>#黄酮类食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103215, encryptionId=ae0e103215ab, topicName=黄酮类食物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Fri Dec 16 13:22:00 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=154810, encodeId=c3c915481059, content=哎呀,观念大转, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ff901728138, createdName=1dedfe95m66(暂无匿称), createdTime=Thu Nov 10 15:24:03 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1416740, encodeId=3dfd1416e40f8, content=<a href='/topic/show?id=27c710101804' target=_blank style='color:#2F92EE;'>#食物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101018, encryptionId=27c710101804, topicName=食物)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e3a33221853, createdName=yhy100201, createdTime=Tue Nov 01 01:22:00 CST 2016, time=2016-11-01, status=1, ipAttribution=)]
    2016-11-01 yhy100201
Baidu
map
Baidu
map
Baidu
map