梅奥：胰腺癌术后放疗可显著降低肿瘤复发

2016-01-07 Mechront 译 MedSci原创

梅奥诊所癌症中心的放射肿瘤学家Christopher Hallemeier博士发现，对胰腺癌术后患者进行放疗可降低癌症复发率，就像化疗一样，是胰腺癌患者的重要治疗方式。该研究共纳入458名胰腺癌术后患者，其中378名患者术后接受化疗和放疗，80名患者术后只接受化疗。研究数据显示，诊断后5年内，进行化疗和放疗的患者中有80%的人放疗部位、肿瘤床和淋巴结没有发现复发，而术后仅化疗组该数据为68%。此外

梅奥诊所癌症中心的放射肿瘤学家Christopher Hallemeier博士发现，对胰腺癌术后患者进行放疗可降低癌症复发率，就像化疗一样，是胰腺癌患者的重要治疗方式。

该研究共纳入458名胰腺癌术后患者，其中378名患者术后接受化疗和放疗，80名患者术后只接受化疗。研究数据显示，诊断后5年内，进行化疗和放疗的患者中有80%的人放疗部位、肿瘤床和淋巴结没有发现复发，而术后仅化疗组该数据为68%。此外接受放疗的患者生存时间更长。

过去五年时间左右，胰腺癌患者术后进行化疗和放疗的趋势越来越明显。Hallemeier和同事打算进行研究探究术后放疗对胰腺癌患者究竟有没有益处。现有的关于该问题的研究结果存在争议，而Hallemeier进行的这项大型研究结果表明，胰腺癌患者术后化疗加放疗可减少癌症复发率。

胰腺癌是导致死亡的第四大原因，并且发病率呈上升趋势，美国每年约有50000人诊断为胰腺癌，约有一半患者出现转移而不能进行手术治疗。历史数据显示，仅仅7%的患者可以在诊断后存活5年以上。只有15%的患者癌肿孤立，可以行手术切除；35%的患者癌肿侵犯胰腺外的血管；还有一些术前进行化疗和放疗的患者，手术虽然复杂但也不是没有可能。

Hallemeier说：“我们意识到对一些可能进行手术的患者，可以术前进行化疗等，观察疗效反应，然后选择放疗，才能为患者选择最受益的个体化治疗方案。”

原始出处：

Predictors of Locoregional Failure and the Impact on Overall Survival in Patients with Resected Exocrine Pancreas Cancer, Kenneth W. Merrell, MD,et al,International Journal of Radiation Oncology, Biology, Physics,7 November 2015.

Mayo study: Radiation an important addition to treatment for pancreatic cancer surgery candidates

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2016-01-19 AspirantSuo

#肿瘤复发#

75 0
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2016-04-23 忠诚向上

好好看看学习

43 0
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2016-04-23 忠诚向上

好好看看学习

138 0
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2016-04-23 忠诚向上

好好看看学习

148 0
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2016-04-23 忠诚向上

好好看看学习

129 0
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2016-04-23 忠诚向上

好好看看学习

168 0
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2016-04-23 忠诚向上

好好看看学习

119 0
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2016-04-23 忠诚向上

好好看看学习

118 0
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2016-04-23 忠诚向上

好好看看学习

173 0
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2016-04-23 忠诚向上

好好看看学习

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