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Oncotarget:1w+病例分析汉族人群中的牛皮癣特征

2017-08-26 Emma MedSci原创

牛皮癣是一种常见的具有特征性皮损的慢性易于复发的炎症性皮肤病。初起为炎性红色丘疹,约粟粒至绿豆大小,以后逐渐扩大或融合成为棕红色斑块,边界清楚,周围有炎性红晕,基底浸润明显,表面覆盖多层干燥的灰白色或银白色鳞屑。

牛皮癣是一种常见的具有特征性皮损的慢性易于复发的炎症性皮肤病。初起为炎性红色丘疹,约粟粒至绿豆大小,以后逐渐扩大或融合成为棕红色斑块,边界清楚,周围有炎性红晕,基底浸润明显,表面覆盖多层干燥的灰白色或银白色鳞屑。为了表征汉族人群的牛皮癣,研究人员进行前瞻性全国和医院调查,位于中国33个城市的56家医院皮肤科参与。

其中包括2009年至2010年注册的12,031名牛皮癣门诊患者,其数据采用标准问卷收集。主要数据采集包括人口统计学相关特征,家族史,疾病状况和其他合并症。进行物理和皮肤病学检查,应用包括体表面积(BSA)和牛皮癣面积严重程度指数(PASI)来评估疾病严重程度。统计分析采用描述性统计、2尾t检验和卡方检验。

研究发现男女比例为1.49:1。男性平均发病年龄为30.2±14.5岁,女性为27.1±15.6岁(P <0.05)。头皮是最常见的发病部位(52.8%),平均PASI为18.70±10.01,表明大多数在医院的患者都有中重度银屑病,多数是牛皮癣(96.5%)。在12,031例患者中,23.1%患者有牛皮癣家族史,16.1%患者患有合并症,29.9%患者有指甲变化。最重要的加重因素是季节变化(60.2%),其次是心理压力(34.5%),性别差异在触发因素上有显着差异。

原始出处:
Chen K, et al. Clinic characteristics of psoriasis in China: a nationwide survey in over 12000 patients. Oncotarget. 2017 Jul 11;8(28):46381-46389. doi: 10.18632/oncotarget.18453.

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    2018-02-02 仁医06
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    2017-08-29 游手好闲

    学习了

    0

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    2017-08-26 Y—xianghai

    学习了新知识

    0

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