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Heart:年轻吸烟者更容易发生急性STEMI

2016-12-01 MedSci MedSci原创

正如每个香烟盒上印着的吸烟有害健康一样,吸烟会增加心脏病的发生风险。近日,来自英国南约克郡心胸中心的一项新的研究着眼于探究年轻吸烟者患心脏病的风险,其研究结果已发表于Heart。研究共纳入了1727名正在接受STEMI治疗患者。其中1727名患者(48.5%)目前仍在吸烟。27%以上的参与者已戒烟,25%的参与者为非吸烟者。结果发现:与戒烟者和非吸烟者的STEMI发病率总和相比,当前吸烟者STEM

正如每个香烟盒上印着的吸烟有害健康一样,吸烟会增加心脏病的发生风险。近日,来自英国南约克郡心胸中心的一项新的研究着眼于探究年轻吸烟者患心脏病的风险,其研究结果已发表于Heart。

研究共纳入了1727名正在接受STEMI治疗患者。其中1727名患者(48.5%)目前仍在吸烟。27%以上的参与者已戒烟,25%的参与者为非吸烟者。

结果发现:

  • 与戒烟者和非吸烟者的STEMI发病率总和相比,当前吸烟者STEMI的发生风险高3倍。

  • 与非吸烟者相比,吸烟者发生外周血管疾病的风险也高3倍。在血管性疾病中,脂肪沉积在动脉中,并阻断腿部的血液供应。

  • 与戒烟者相比,目前吸烟者冠状动脉疾病的发生风险为其2倍。

  • 与戒烟者及非吸烟者相比,当前吸烟者患STEMI的年龄较其年轻10-11岁。

  • 当前吸烟者中,发生STEMI风险最高的年龄段为50岁以下,这年龄段人群发生STEMI的风险为非吸烟者和戒烟者风险联合的近8.5倍。

  • STEMI的发生风险与年龄呈负相关,意味着随着年龄的增长STEMI的发生风险不断升高。例如,50-65岁之间的成年人,STEMI的发生风险下降到5倍,而65岁以上吸烟者STEMI的发生风险只有3倍。

  • 50岁以下的STEMI患者中,吸烟者占75%。

该研究首次使用人口数据和病例数据说明年轻吸烟者急性STEMI的发作风险高于老年吸烟者,有助于指导健康政策的制定,还可提高当前社会对吸烟、年龄与健康相关的看法。

但是本研究仍存在一些局限性,如观察性研究并不能解释年轻吸烟者急性STEMI的发作风险高的原因,也并没有校正如血压、糖尿病等混杂因素,研究也未考虑入院前死亡的患者,以及那些不适合经皮冠状动脉介入治疗的患者。

原始出处:

Amelia Lloyd et al., Pronounced increase in risk of acute ST-segment elevation myocardial infarction in younger smokers. Heart, 29 November 2016.

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createdTime=Mon Dec 05 07:50:33 CST 2016, time=2016-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160181, encodeId=729a16018148, content=需要及时戒烟, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:48:19 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160180, encodeId=613316018019, content=吸烟有害健康的, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-07 xiehhtt

    保命要紧,今天开始戒烟

    0

  2. 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href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-05 幸运8355

    及时戒烟和控烟是很重要的

    0

  3. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-05 幸运8355

    需要及时戒烟

    0

  4. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-05 幸运8355

    吸烟对健康危害是很大的

    0

  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-04 幸运8355

    需要及时戒烟

    0

  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-04 幸运8355

    吸烟有害健康的

    0

  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-04 幸运8355

    很多疾病是和吸烟有很大的关系

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-04 幸运8355

    希望每天都有新的内容

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:47:15 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=160177, encodeId=54d81601e71d, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6lR0HdZibhWZ60R0PbDKxKOKTx2cxC1B8bqCg5WFj3DV4YaTBzJv9RrNyScwZ6wVicroZ2As62f2cIA1SfN8hJAB/0, createdBy=6e241959371, createdName=幸运8355, createdTime=Sun Dec 04 11:46:52 CST 2016, time=2016-12-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605097, encodeId=a070160509efd, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Sat Dec 03 13:27:00 CST 2016, time=2016-12-03, status=1, ipAttribution=)]
    2016-12-04 幸运8355

    继续关注

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