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这次3D打印技术要让Ⅰ型糖尿病患者受益啦!

2015-06-02 佚名 奇点网

对于Ⅰ型糖尿病患者来说,“胰岛移植”这种实验性手术也许可以帮助他们解决胰岛素缺乏的问题。这种手术将健康捐献者的胰岛细胞移植到Ⅰ型糖尿病患者体内,但是带来的副作用则是患者需要终身服用免疫抑制类药物以防止身体对外来植入细胞产生排斥反应。最近,科学家找到了一种新的办法–利用3D打印的支架对移植胰岛细胞进行保护。这种技术展示出了巨大潜力,有望帮助Ⅰ型糖尿病患者更轻松的管理自己的疾病。 Ⅰ型糖尿病

对于Ⅰ型糖尿病患者来说,“胰岛移植”这种实验性手术也许可以帮助他们解决胰岛素缺乏的问题。这种手术将健康捐献者的胰岛细胞移植到Ⅰ型糖尿病患者体内,但是带来的副作用则是患者需要终身服用免疫抑制类药物以防止身体对外来植入细胞产生排斥反应。最近,科学家找到了一种新的办法–利用3D打印的支架对移植胰岛细胞进行保护。这种技术展示出了巨大潜力,有望帮助Ⅰ型糖尿病患者更轻松的管理自己的疾病。
 
Ⅰ型糖尿病患者很害怕血糖过低,因为这会引发一系列并发症(低血糖症),包括头晕、出汗甚至是失去知觉和死亡等。Diabetes UK数据显示,大约1/3的Ⅰ型糖尿病患者都被低血糖症困扰着。
 
为了改善胰岛移植手术的成功率和提高Ⅰ型糖尿病患者的生活质量,荷兰特文特大学的研究人员打造了特殊的支架设备保护胰岛细胞。他们的想法是利用3D打印支架设备保护胰岛细胞免受患者免疫系统的攻击,为其更好地发挥功能创造条件。
 

 
研究人员用藻朊酸盐和凝胶制成支架设备,并将胰岛细胞嵌入其中。这款支架没有采用固体结构,而是采用了多孔设计。研究人员称这有利于葡萄糖和胰岛素之间产生理想的交换。由混合材料制成支架的厚度和粘性同样至关重要。它必须足够结实牢固,这样研究人员才可以用3D打印机完成打印工作。但又不能太过于紧实,以免影响嵌入其中的胰岛细胞发挥作用。
 
研究人员在实验室中发现,嵌入3D打印支架设备中的胰岛细胞能像正常的胰岛细胞一样发挥作用。这意味着利用支架设备的运输方式并不影响胰岛细胞自身功能,而且可以为其提供有效保护,免受身体免疫系统攻击和排斥。
 

研究的联合作者之一A A van Apeidoorn博士说:“如果我们想要提高Ⅰ型糖尿病患者胰岛移植手术的成功率,那就要以嵌入或者密封的形式向人体注入胰岛细胞。选择保护材料时,既要考虑到胰岛细胞能从人体内获得高效的氧气和营养供给,又要考虑到葡萄糖和胰岛素的快速交换。当然我们还不能让宿主细胞进入保护装置,从而避免排斥反应。”
 
这项研究目前已经发表在《Institute of Physics》上。
 

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=71957, encodeId=411ee195794, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71958, encodeId=687ee19583e, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71959, encodeId=b0b5e19596a, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71960, encodeId=d612e1960ca, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71961, encodeId=072de1961c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71962, encodeId=31b8e196232, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71963, encodeId=4b9fe1963d1, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71964, encodeId=ef85e196488, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977882, encodeId=5bd519e788245, content=<a href='/topic/show?id=53361230f8' target=_blank style='color:#2F92EE;'>#3D打印技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1230, encryptionId=53361230f8, topicName=3D打印技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sun Oct 25 07:49:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1335873, encodeId=eb7c13358e357, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Thu Jun 04 00:49:00 CST 2015, time=2015-06-04, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=71957, encodeId=411ee195794, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71958, encodeId=687ee19583e, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71959, encodeId=b0b5e19596a, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71960, encodeId=d612e1960ca, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71961, encodeId=072de1961c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71962, encodeId=31b8e196232, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71963, encodeId=4b9fe1963d1, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71964, encodeId=ef85e196488, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977882, encodeId=5bd519e788245, content=<a href='/topic/show?id=53361230f8' target=_blank style='color:#2F92EE;'>#3D打印技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1230, encryptionId=53361230f8, topicName=3D打印技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sun Oct 25 07:49:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1335873, encodeId=eb7c13358e357, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Thu Jun 04 00:49:00 CST 2015, time=2015-06-04, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=71957, encodeId=411ee195794, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71958, encodeId=687ee19583e, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71959, encodeId=b0b5e19596a, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71960, encodeId=d612e1960ca, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71961, encodeId=072de1961c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71962, encodeId=31b8e196232, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71963, encodeId=4b9fe1963d1, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71964, encodeId=ef85e196488, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977882, encodeId=5bd519e788245, content=<a href='/topic/show?id=53361230f8' target=_blank style='color:#2F92EE;'>#3D打印技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1230, encryptionId=53361230f8, topicName=3D打印技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sun Oct 25 07:49:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1335873, encodeId=eb7c13358e357, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Thu Jun 04 00:49:00 CST 2015, time=2015-06-04, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=71957, encodeId=411ee195794, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71958, encodeId=687ee19583e, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71959, encodeId=b0b5e19596a, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=186, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71960, encodeId=d612e1960ca, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=117, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71961, encodeId=072de1961c0, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=147, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71962, encodeId=31b8e196232, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71963, encodeId=4b9fe1963d1, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=104, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=71964, encodeId=ef85e196488, content=仔细阅读,好好品味, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sun Mar 20 10:03:00 CST 2016, time=2016-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1977882, encodeId=5bd519e788245, content=<a href='/topic/show?id=53361230f8' target=_blank style='color:#2F92EE;'>#3D打印技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1230, encryptionId=53361230f8, topicName=3D打印技术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30f5146, createdName=zz70, createdTime=Sun Oct 25 07:49:00 CST 2015, time=2015-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1335873, encodeId=eb7c13358e357, content=<a href='/topic/show?id=792612047e' target=_blank style='color:#2F92EE;'>#3D#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1204, encryptionId=792612047e, topicName=3D)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/pSGl6CJeZ2PzWxdhCtrvv4U9Q281RV8e0AKmlB5ib93DibbiaRyOzmkCdz5F04cbfX5RGOpG4dOXvuQW1fumibVeBg/132, createdBy=fc342500110, createdName=ms9833124466084992, createdTime=Thu Jun 04 00:49:00 CST 2015, time=2015-06-04, status=1, ipAttribution=)]
    2016-03-20 忠诚向上

    仔细阅读,好好品味

    0

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    2016-03-20 忠诚向上

    仔细阅读,好好品味

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