Baidu
map

PNAS:过长时间暴露于光线下可导致体重增加!!

2015-05-14 佚名 生物谷

来自荷兰Leiden大学医学中心和学术医学中心的两个研究团队联合研究发现了,长时间暴露在光线下的小鼠体重增加的原因。他们发表于PNAS杂志上的文章描述了,他们是如何检测了当小鼠在长时间地暴露于不同量的光线后,这些小鼠的食物燃烧效率以及其与体重增加的关系。科学家们已知过度暴露于光线下,或者是在奇怪的时间段暴露于光线下,会引起人们的体重增加,随之而来导致一些疾病发生。但是,为什么会是这样的,现在仍不清

来自荷兰Leiden大学医学中心和学术医学中心的两个研究团队联合研究发现了,长时间暴露在光线下的小鼠体重增加的原因。他们发表于PNAS杂志上的文章描述了,他们是如何检测了当小鼠在长时间地暴露于不同量的光线后,这些小鼠的食物燃烧效率以及其与体重增加的关系。

科学家们已知过度暴露于光线下,或者是在奇怪的时间段暴露于光线下,会引起人们的体重增加,随之而来导致一些疾病发生。但是,为什么会是这样的,现在仍不清 楚。许多人们,尤其是那些上夜班的人们,他们认为他们的体重增加是因为,长时间的工作及不规律的日程安排引起的增长的压力导致的。在这项新的研究工作中, 看起来这些人可能是对的,但并不是他们所认为的那样。

为了研究清楚人们(或是在此研究中的小鼠)为什么在每天长时间地暴露于光线下,会引起体重增加,研究团队将小鼠饲养在日/夜交替可改变的环境里-不同的小组生活在人造光源下12,16和24小时,为期1个月。研究人员们猜测棕色脂肪组织在此过程中起了一定的作用,所以他们监测了所有小鼠的棕色脂肪的效率。棕色脂肪在将食物转换为热量的过程中起到了重要的作用。如果食物中的能量没有被转化为热量,那么就会被储存为脂肪。

在监测棕色脂肪效率水平的时候,研究团队发现,那些暴露在长时间光线下的小鼠不仅仅是体重有所增加(尽管它们和对照组的小鼠吃相同量的食物和进行同样的运动),而且它们的棕色脂肪的效率也有所下降。因此,长时间的暴露于光线下,可以使机体储存更多的食物能量,而不是把这些能量转化为热量。研究团队提示这同样适用于人类,回到远古时代,夏天(更多的光照时间)对人们就意味着储存起脂肪,以在寒冷的冬季御寒。


原始出处:


Sander Kooijmana, Rosa van den Berga, Ashna Ramkisoensingc, Mariëtte R. Boona,b, Eline N. Kuipersa, Marieke Loefa, Tom C. M. Zonnevelda, Eliane A. Lucassenc, Hetty C. M. Sipsa, Iliana A. Chatzispyroud, Riekelt H. Houtkooperd, Johanna H. Meijerc, Claudia P. Coomansc, Nienke R. Biermasza, and Patrick C. N. Rensena.Prolonged daily light exposure increases body fat mass through attenuation of brown adipose tissue activity.PNAS, May 11, 2015.doi: 10.1073/pnas.1504239112 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1855730, encodeId=455e1855e3060, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Sun Sep 06 14:51:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23916, encodeId=4446239166f, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 17 20:07:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23808, encodeId=0d0323808de, content=减肥思路啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Sun May 17 07:43:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298193, encodeId=6b55129819353, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sat May 16 05:51:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23572, encodeId=4f86235e295, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Fri May 15 07:42:00 CST 2015, time=2015-05-15, status=1, ipAttribution=)]
    2015-09-06 drwjr
  2. [GetPortalCommentsPageByObjectIdResponse(id=1855730, encodeId=455e1855e3060, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Sun Sep 06 14:51:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23916, encodeId=4446239166f, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 17 20:07:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23808, encodeId=0d0323808de, content=减肥思路啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Sun May 17 07:43:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298193, encodeId=6b55129819353, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sat May 16 05:51:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23572, encodeId=4f86235e295, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Fri May 15 07:42:00 CST 2015, time=2015-05-15, status=1, ipAttribution=)]
    2015-05-17 huaxipanxing

    看看

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1855730, encodeId=455e1855e3060, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Sun Sep 06 14:51:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23916, encodeId=4446239166f, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 17 20:07:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23808, encodeId=0d0323808de, content=减肥思路啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Sun May 17 07:43:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298193, encodeId=6b55129819353, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sat May 16 05:51:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23572, encodeId=4f86235e295, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Fri May 15 07:42:00 CST 2015, time=2015-05-15, status=1, ipAttribution=)]
    2015-05-17 Dr.LV

    减肥思路啊

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1855730, encodeId=455e1855e3060, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Sun Sep 06 14:51:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23916, encodeId=4446239166f, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 17 20:07:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23808, encodeId=0d0323808de, content=减肥思路啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Sun May 17 07:43:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298193, encodeId=6b55129819353, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sat May 16 05:51:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23572, encodeId=4f86235e295, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Fri May 15 07:42:00 CST 2015, time=2015-05-15, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=1855730, encodeId=455e1855e3060, content=<a href='/topic/show?id=f32014428fc' target=_blank style='color:#2F92EE;'>#PNAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14428, encryptionId=f32014428fc, topicName=PNAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=08e964, createdName=drwjr, createdTime=Sun Sep 06 14:51:00 CST 2015, time=2015-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23916, encodeId=4446239166f, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Sun May 17 20:07:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23808, encodeId=0d0323808de, content=减肥思路啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUNfdk68bHutYruGyxbKDzPWH3agcmId19Yf94FiapyicN0LTg0jykhqIhjPQVdR08FGR399rBpZIg/132, createdBy=feae1624323, createdName=Dr.LV, createdTime=Sun May 17 07:43:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298193, encodeId=6b55129819353, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Sat May 16 05:51:00 CST 2015, time=2015-05-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23572, encodeId=4f86235e295, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=123, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Fri May 15 07:42:00 CST 2015, time=2015-05-15, status=1, ipAttribution=)]
    2015-05-15 zhouanxiu

    有意思

    0

相关资讯

Obesity:代谢手术后即使女性体重稳定不变,内脏和肌间脂肪组织也持续减少

研究证明,代谢手术可以显著的降低体重,而且脂肪组织总量的降低占总体重减少量的80%,而且,身体不同部位的脂肪组织沉积会导致与肥胖相关的各种不同的并发症,如胰岛素抵抗和心血管疾病。目前,代谢手术对脂肪组织沉积的影响仍不清楚。大多数的研究使用单一的腹部切片来评估内脏脂肪组织和皮下脂肪组织的贮存情况。最近,来自纽约的Tatiana Toro-Ramos和他的团队,使用全身的MRI,来评估代谢手术前和代谢

Obesity:肥胖孕妈妈一定要控制好体重

已有相当多的研究表明,孕妇肥胖会导致大于胎龄儿(LGA)和小于胎龄儿(SGA)的风险增加,导致后代肥胖风险增加。Catov JM等人进行了一项研究,想探究不同孕期体重增长(GWG)模式与LGA、SGA发生率间的联系,以及何种GWG模式可以减少或抵消此类风险。

ENDO 2015:每天失去30分钟睡眠可促使体重增加,并对血糖控制产生不利影响

一项新的调查研究显示,每天少睡30分钟会对体重和代谢产生长期的影响。该研究结果于2015年3月5日圣地亚哥内分泌学年会上发表。 “虽然以前的研究表明,睡眠时间短与肥胖和糖尿病有关,我们发现,短短30分钟的睡眠可能对肥胖和胰岛素抵抗有显著的影响,”本研究的主要作者,多哈卡塔尔威尔康乃尔医学院的Shahrad Taheri教授说。“这加强了早些时候对睡眠可影响新陈代谢研究的证据。” &nb

Diabetes专家观点:2014糖尿病重大治疗突破的回顾

总结刚刚过去的2014,不难发现,关于糖尿病的治疗策略有许多重要的突破。作为Journal of Diabetes的编辑,Zachary博士和我的团队一直在努力呈现最新的糖尿病治疗和研究进展。Zachary博士说:“关于糖尿病的治疗,我们一直在努力寻找既能有效的控制血糖,又不增加传统治疗带来的高胰岛素血症、低血糖症及体重增加风险的治疗方法。”目前,在2型糖尿病治疗上,我们首选二甲双胍,而不是磺脲类

Pediatrics:一切为了孩子,孕前请减肥

最近几十年肥胖和发育障碍的发生率在增加,目前只有极少的研究探究了母亲孕前肥胖和儿童神经发育之间的联系。因此Jo H等人对1311对母子进行了回顾性和随访研究,探究母亲孕前体重指数(BMI)和儿童心理发展之间的联系。该研究根据孕产妇对孩子优缺点问卷的回答、过去相关发育诊断、需要特殊照顾服务等评估后代的发展情况。 校正社会人口因素后发现,与BMI正常的母亲

Lancet Diabetes Endocrinol:太瘦之人容易痴呆

中年时体重过低可增加晚年发生痴呆的风险,而超重或肥胖可防止痴呆的发生。近期,The Lancet Diabetes & Endocrinology上报道了一项关于BMI与痴呆风险的大型研究。 本文作者Nawab Qizilbashsh,来自英国London School of Hygiene and Tropical Medicine ,说道:“我们的研究结果与以往许多的研究结果

Baidu
map
Baidu
map
Baidu
map