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Am Heart J：耐力训练无益于射血分数正常心衰患者

2012-11-07 Am Heart J Am Heart J

耐力训练射血分数正常心衰心力衰竭
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　　美国学者的一项研究表明，为期1年的耐力训练未能改善射血分数正常心衰（HFPEF）患者的心血管僵硬度和功能。论文于2012年10月31日在线发表于《美国心脏杂志》（Am Heart J）。 　　此项研究共纳入11例HFPEF患者和13例健康对照者。采用有创右心导管测定Starling和左室压力-容积曲线；次要功能转归包括超声心动图、动脉硬度、心肺运动试验和心室-动脉偶联。7

　　美国学者的一项研究表明，为期1年的耐力训练未能改善射血分数正常心衰（HFPEF）患者的心血管僵硬度和功能。论文于2012年10月31日在线发表于《美国心脏杂志》（Am Heart J）。

　　此项研究共纳入11例HFPEF患者和13例健康对照者。采用有创右心导管测定Starling和左室压力-容积曲线；次要功能转归包括超声心动图、动脉硬度、心肺运动试验和心室-动脉偶联。7例HFPEF患者完成1年耐力训练并接受重复检查。基线时测定肺毛细血管楔压和左室舒张末期容积，通过压力-容积曲线斜度评估左室顺应性。

　　结果显示，与对照组相比，训练之前HFPEF患者的运动能力、膨胀性、动态Starling机制均减弱，充盈压和室壁应力升高，但左室顺应性和舒张末期容积相似。为期1年的训练对左室顺应性和容积、动脉硬度、运动能力和心室-动脉偶联均影响甚微。

　　链接：Cardiovascular effects of 1 year of progressive endurance exercise training in patients with heart failure with preserved ejection fraction



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  1. [GetPortalCommentsPageByObjectIdResponse(id=1994287, encodeId=3c0e199428e0d, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Fri May 17 04:04:00 CST 2013, time=2013-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926680, encodeId=2ad719266804d, content=<a href='/topic/show?id=c02d803449e' target=_blank style='color:#2F92EE;'>#耐力训练#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80344, encryptionId=c02d803449e, topicName=耐力训练)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb0b97, createdName=zhangxingru, createdTime=Fri Nov 16 12:04:00 CST 2012, time=2012-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309446, encodeId=a0da130944669, content=<a href='/topic/show?id=83154681088' target=_blank style='color:#2F92EE;'>#射血分数正常心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46810, encryptionId=83154681088, topicName=射血分数正常心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5d7367, createdName=zhwj, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355696, encodeId=27a41355696bb, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373241, encodeId=849613e324150, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562112, encodeId=9f5d156211262, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=)]
    2013-05-17 caoliehu

    #射血分数正常#

    0

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    2012-11-16 zhangxingru

    #耐力训练#

    0

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    2012-11-09 zhwj

    #射血分数正常心衰#

    0

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    2012-11-09 zhaojie88

    #ART#

    0

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    2012-11-09 yuanming7

    #心衰患者#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1994287, encodeId=3c0e199428e0d, content=<a href='/topic/show?id=b67646808b9' target=_blank style='color:#2F92EE;'>#射血分数正常#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46808, encryptionId=b67646808b9, topicName=射血分数正常)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=316c73, createdName=caoliehu, createdTime=Fri May 17 04:04:00 CST 2013, time=2013-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926680, encodeId=2ad719266804d, content=<a href='/topic/show?id=c02d803449e' target=_blank style='color:#2F92EE;'>#耐力训练#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=80344, encryptionId=c02d803449e, topicName=耐力训练)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb0b97, createdName=zhangxingru, createdTime=Fri Nov 16 12:04:00 CST 2012, time=2012-11-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309446, encodeId=a0da130944669, content=<a href='/topic/show?id=83154681088' target=_blank style='color:#2F92EE;'>#射血分数正常心衰#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=85, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=46810, encryptionId=83154681088, topicName=射血分数正常心衰)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5d7367, createdName=zhwj, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355696, encodeId=27a41355696bb, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373241, encodeId=849613e324150, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562112, encodeId=9f5d156211262, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Nov 09 01:04:00 CST 2012, time=2012-11-09, status=1, ipAttribution=)]
    2012-11-09 slcumt

    #HEART#

    0

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