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欧洲专利局将批准默克的CRISPR技术专利申请

2017-08-04 默克 默克

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-- 专利申请涵盖利用CRISPR将外部DNA序列整合进真核细胞染色体
-- 相关专利最近在澳大利亚获批;类似专利在其它国家待批,有望获得积极成果

领先科技公司默克(Merck)今天宣布,欧洲专利局(European Patent Office)已下发默克专利申请的“批准意向通知”。申请涵盖该公司用于真核细胞基因组整合方法的CRISPR技术。

默克的专利申请涵盖利用CRISPR将外部DNA序列整合进真核细胞染色体。这项专利将为默克的CRISPR基因组整合技术提供更多保护,进一步增强该公司的专利组合。
默克的专利申请涵盖利用CRISPR将外部DNA序列整合进真核细胞染色体。这项专利将为默克的CRISPR基因组整合技术提供更多保护,进一步增强该公司的专利组合。

这项专利将为默克的CRISPR基因组整合技术提供更多保护,进一步增强该公司的专利组合。2017年6月份,一项相关专利已在澳大利亚获批。默克预计在其它国家也能取得积极成果,因为全球很多专利局都会考虑相关欧洲案例的地位与批准专利的决定高度相关。

默克执行委员会委员、Life Science首席执行官Udit Batra表示:“这是欧洲专利局做出的重要而振奋人心的决定,我们认为这项公告是对默克在基因组编辑领域重要贡献的认可。这项专利将为我们的CRISPR技术提供保护,这将让科学家能够为我们当今所面临的最艰巨医学挑战改进治疗选择。”

凭借默克的基因组整合技术,科学家能够以有益的功能性序列替代疾病相关突变,这是建立疾病模型和得出基因疗法的重要方法。科学家还可以用这个方法来插入转基因,实现基础研究。比如,用这项技术来标记内源性蛋白,用于基因内的可视化跟踪。

这项专利申请是默克自2012年以来提交的众多CRISPR申请之一。2017年5月,默克推出了一种名为proxy-CRISPR的替代性CRISPR基因编辑方法。和其它系统不同,proxy-CRISPR技术实现了以前无法到达的细胞区域的切割,让CRISPR更高效、更灵活、更具有特征性,为研究人员提供了更多实验选择。

默克在基因组编辑领域拥有14年的历史,是第一家在全球范围内为基因组编辑提供定制生物分子(TargeTron™ RNA引导II型内含子和CompoZr™锌指核酸酶)的公司,推动全球研究领域采用这些技术。通过与Wellcome Trust Sanger Institute的合作,默克还是第一家制造覆盖整个人类基因组的CRISPR序列库的公司,让研究人员能够探究更多关于疾病的问题,由此加快治愈疾病的进程。CRISPR序列库是基因组编辑领域的重要进步,巩固了该公司的领导地位。

除了开展基础的基因组编辑研究,该公司还支持开发基于基因和细胞的疗法,并生产病毒载体。2016年,默克推出了一项计划,旨在通过专门的团队和更加强大的资源来推动新治疗方式的研究,包括基因组编辑和基因药物制造,等等。这项计划进一步强化了该公司对基因组编辑领域的承诺。

默克的所有新闻稿会在发布于默克网站的同时通过邮件发送。请前往www.merckgroup.com/subscribe进行在线注册、更改选项或停止此项服务。

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    2017-08-06 yuandd
  5. [GetPortalCommentsPageByObjectIdResponse(id=1704912, encodeId=710c1e04912e5, content=<a href='/topic/show?id=71742062668' target=_blank style='color:#2F92EE;'>#专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20626, encryptionId=71742062668, topicName=专利申请)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e7a30885975, createdName=zhangjingnwpu, createdTime=Wed May 30 06:22:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783827, encodeId=ff1d1e8382736, content=<a href='/topic/show?id=967a524198' target=_blank style='color:#2F92EE;'>#CRISPR技术专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5241, encryptionId=967a524198, topicName=CRISPR技术专利申请)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Sun Nov 26 00:22:00 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1273895, encodeId=0fc512e3895cf, content=<a href='/topic/show?id=4909103353c5' target=_blank style='color:#2F92EE;'>#默克#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103353, encryptionId=4909103353c5, topicName=默克)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ba9118, createdName=makuansheng, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276038, encodeId=fbf312e60387c, content=<a href='/topic/show?id=755d5211a0' target=_blank style='color:#2F92EE;'>#CRISPR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5211, encryptionId=755d5211a0, topicName=CRISPR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339019, encodeId=4ae7133901991, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618700, encodeId=5a461618e00c3, content=<a href='/topic/show?id=e798524076' target=_blank style='color:#2F92EE;'>#Crispr技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5240, encryptionId=e798524076, topicName=Crispr技术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a49419938232, createdName=ms1779634646866130, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230139, encodeId=30fd23013908, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Aug 05 05:13:00 CST 2017, time=2017-08-05, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1704912, encodeId=710c1e04912e5, content=<a href='/topic/show?id=71742062668' target=_blank style='color:#2F92EE;'>#专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20626, encryptionId=71742062668, topicName=专利申请)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e7a30885975, createdName=zhangjingnwpu, createdTime=Wed May 30 06:22:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783827, encodeId=ff1d1e8382736, content=<a href='/topic/show?id=967a524198' target=_blank style='color:#2F92EE;'>#CRISPR技术专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5241, encryptionId=967a524198, topicName=CRISPR技术专利申请)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Sun Nov 26 00:22:00 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1273895, encodeId=0fc512e3895cf, content=<a href='/topic/show?id=4909103353c5' target=_blank style='color:#2F92EE;'>#默克#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103353, encryptionId=4909103353c5, topicName=默克)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ba9118, createdName=makuansheng, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276038, encodeId=fbf312e60387c, content=<a href='/topic/show?id=755d5211a0' target=_blank style='color:#2F92EE;'>#CRISPR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5211, encryptionId=755d5211a0, topicName=CRISPR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339019, encodeId=4ae7133901991, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618700, encodeId=5a461618e00c3, content=<a href='/topic/show?id=e798524076' target=_blank style='color:#2F92EE;'>#Crispr技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5240, encryptionId=e798524076, topicName=Crispr技术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a49419938232, createdName=ms1779634646866130, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230139, encodeId=30fd23013908, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Aug 05 05:13:00 CST 2017, time=2017-08-05, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1704912, encodeId=710c1e04912e5, content=<a href='/topic/show?id=71742062668' target=_blank style='color:#2F92EE;'>#专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20626, encryptionId=71742062668, topicName=专利申请)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e7a30885975, createdName=zhangjingnwpu, createdTime=Wed May 30 06:22:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1783827, encodeId=ff1d1e8382736, content=<a href='/topic/show?id=967a524198' target=_blank style='color:#2F92EE;'>#CRISPR技术专利申请#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5241, encryptionId=967a524198, topicName=CRISPR技术专利申请)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a885259, createdName=yourmama, createdTime=Sun Nov 26 00:22:00 CST 2017, time=2017-11-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1273895, encodeId=0fc512e3895cf, content=<a href='/topic/show?id=4909103353c5' target=_blank style='color:#2F92EE;'>#默克#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103353, encryptionId=4909103353c5, topicName=默克)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2ba9118, createdName=makuansheng, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1276038, encodeId=fbf312e60387c, content=<a href='/topic/show?id=755d5211a0' target=_blank style='color:#2F92EE;'>#CRISPR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5211, encryptionId=755d5211a0, topicName=CRISPR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=583c133, createdName=yuandd, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1339019, encodeId=4ae7133901991, content=<a href='/topic/show?id=447663054f5' target=_blank style='color:#2F92EE;'>#欧洲#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=63054, encryptionId=447663054f5, topicName=欧洲)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/PiajxSqBRaEKxsKDoOOFxGpMibw6lsQFUIicWt7kWGevkdgFhjiban1icD2JdIBmjVo7qX7aSlCSpiaia382nuLKiaI3Cg/132, createdBy=5c442500150, createdName=ms9474365431325850, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1618700, encodeId=5a461618e00c3, content=<a href='/topic/show?id=e798524076' target=_blank style='color:#2F92EE;'>#Crispr技术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5240, encryptionId=e798524076, topicName=Crispr技术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a49419938232, createdName=ms1779634646866130, createdTime=Sun Aug 06 05:22:00 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230139, encodeId=30fd23013908, content=谢谢分享,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Aug 05 05:13:00 CST 2017, time=2017-08-05, status=1, ipAttribution=)]
    2017-08-05 明天会更好!

    谢谢分享,学习了

    0

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