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Neth Heart J.:STEMI患者旋动脉明显收缩预示危险信号

2015-05-05 范伟译 MedSci原创

背景:闭塞的旋动脉(Cx)通常在心电图中不会出现信号。在ST段抬高心肌梗死(STEMI)中,它会导致延迟的血管造影。这个分析的目的是右冠状动脉(RCA)狭窄的STEMI患者,左降动脉(LAD)用经皮冠状动脉介入治疗(PCI)后,确定闭塞的旋动脉收缩与其相比是否会有多样化的结果。方法和结果:入选标准如下:首先STEMI患者的左降动脉(LAD)用经皮冠状动脉介入治疗(PCI),额外明显的(≥70%)闭

背景:闭塞的旋动脉(Cx)通常在心电图中不会出现信号。在ST段抬高心肌梗死(STEMI)中,它会导致延迟的血管造影。这个分析的目的是右冠状动脉(RCA)狭窄的STEMI患者,左降动脉(LAD)用经皮冠状动脉介入治疗(PCI)后,确定闭塞的旋动脉收缩与其相比是否会有多样化的结果。

方法和结果:入选标准如下:首先STEMI患者的左降动脉(LAD)用经皮冠状动脉介入治疗(PCI),额外明显的(≥70%)闭塞的旋动脉或右冠状动脉RCA 收缩-两个-血管疾病。共有234名连续的STEMI患者包括在内。总死亡率在长期随访中评估,STEMI后平均639(±224)天。闭塞的旋动脉收缩的患者占研究人数的46%(N = 108),右冠状动脉RCA收缩的患者达54%(N = 126)。闭塞的旋动脉收缩的患者相比于右冠状动脉RCA收缩的患者就死亡率而言长期结果更差(分别为22 vs 11%,p < 0.05)。多元回归分析显示长期随访中死亡的独立危险因素例如:年龄、射血分数和闭塞的旋动脉收缩。

如图:RCA组与Cx组的比较

结论:明显闭塞的旋动脉收缩相比右冠状动脉(RCA)收缩的STEMI患者其左降动脉(LAD)用经皮冠状动脉介入治疗(PCI)的,其结果更糟糕。
  
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    2015-08-11 canlab
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    2015-05-07 zhaojie88
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    2015-05-07 slcumt
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    2015-05-06 qingfengqishi5

    新的研究方向!

    0

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