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Allergy:儿童和成年人时期,孕期和围产期条件和特应性疾病流行度研究

2017-12-15 AlexYang MedSci原创

之前,在儿童中关于孕期相关的和围产期因素对随后呼吸道和特应性级疾病的影响的研究结果具有争议。最近,有研究人员在儿童和成年人中,评估了围产期变量和哮喘、支气管高反应性、异位性皮肤炎、过敏性鼻炎和致敏之间的相关性。研究群体首次检查在慕尼黑和德累斯顿,时间为1995/1996年,群体的年龄为9-12岁。参与者随后的年龄段位19-24岁。研究人员随后利用调整过的潜在混杂因素的逻辑回归分析,调查了围产期数据

之前,在儿童中关于孕期相关的和围产期因素对随后呼吸道和特应性级疾病的影响的研究结果具有争议。最近,有研究人员在儿童和成年人中,评估了围产期变量和哮喘、支气管高反应性、异位性皮肤炎、过敏性鼻炎和致敏之间的相关性。

研究群体首次检查在慕尼黑和德累斯顿,时间为1995/1996年,群体的年龄为9-12岁。参与者随后的年龄段位19-24岁。研究人员随后利用调整过的潜在混杂因素的逻辑回归分析,调查了围产期数据和随后特应性疾病之间的相关性。研究发现,在年轻成年人中,剖腹产与BHR显著相关(Odds Ratio 4.8, 95% confidence interval 1.5-15.2),并且协助出生与儿童哮喘症状的出现(2.2, 1.2-3.9)、儿童中异位性皮肤炎(2.2, 1.2-4.3)和医生诊断的特应性皮肤炎(1.9, 1.0-3.4)以及年轻成年人中的致敏(2.2, 1.1-4.3)具有相关性。与平均出生长度和出生体重相比,更低的出生长度(1.9, 1.1-3.2)、更低的出生重量(0.5, 0.3-0.9)和更高的出生重量(0.6 (0.4-1.0)是年轻成年人致敏预测标记。其他围产期因素与结果没有显著相关性。

最后,研究人员指出,他们的结果表明了剖腹产以及协助出生,可能是发展成为哮喘、异位性皮肤炎和致敏的风险因子,应该予以监控。产前孕妇压力也许能够部分的解释这些相关性,还需要进一步的研究来阐明这些相关性。

原始出处:

Gerlich J, Benecke N, Peters-Weist AS et al. Pregnancy and perinatal conditions and atopic disease prevalence in childhood and adulthood. Allergy. 29 Nov 2017.

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    2017-12-17 膀胱癌
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    2017-12-16 明天会更好!

    学习了.学习了.

    0

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    2017-12-16 戒馋,懒,贪

    谢谢分享学习了

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1799474, encodeId=cb461e9947408, content=<a href='/topic/show?id=67abe06995a' target=_blank style='color:#2F92EE;'>#疾病流行#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70699, encryptionId=67abe06995a, topicName=疾病流行)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a691420, createdName=30397604, createdTime=Fri Nov 02 13:02:00 CST 2018, time=2018-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651426, encodeId=2c5c165142670, content=<a href='/topic/show?id=3e8a653e2fe' target=_blank style='color:#2F92EE;'>#流行度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65372, encryptionId=3e8a653e2fe, topicName=流行度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=acc724200297, createdName=piaojinhua, createdTime=Wed Jul 25 15:02:00 CST 2018, time=2018-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329045, encodeId=195713290456f, content=<a href='/topic/show?id=bb96232801' target=_blank style='color:#2F92EE;'>#ALL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2328, encryptionId=bb96232801, topicName=ALL)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sun Dec 17 10:02:00 CST 2017, time=2017-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269871, encodeId=c11a2698e194, content=学习了.学习了., beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat Dec 16 15:24:57 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269861, encodeId=291f26986155, content=谢谢分享学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=125, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sat Dec 16 13:46:49 CST 2017, time=2017-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=269846, encodeId=b698269846f6, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Sat Dec 16 12:48:51 CST 2017, time=2017-12-16, status=1, ipAttribution=)]
    2017-12-16 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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