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JCO:视网膜细胞瘤患者心理健康研究

2015-09-30 zhaozhou译 MedSci原创

 美国每年有约350名儿童被诊断为成视网膜细胞瘤(RB)。发达国家的RB的生存率超过95%。尽管有关RB的二次肿瘤发病的风险增高的研究已有很多,但是有关RB对于患者长期的心理作用的影响仍然鲜有研究报道。 研究人员通过邮件或者电话采访收集了从1932年到1994年并且在纽约进行治疗的成年RB幸存者的综合调查问卷。问卷改编自儿童癌症幸存者研究(Childhood Cancer Su

美国每年有约350名儿童被诊断为视网膜细胞瘤(RB)。发达国家的RB的生存率超过95%。尽管有关RB的二次肿瘤发病的风险增高的研究已有很多,但是有关RB对于患者长期的心理作用的影响仍然鲜有研究报道。


研究人员通过邮件或者电话采访收集了从1932年到1994年并且在纽约进行治疗的成年RB幸存者的综合调查问卷。问卷改编自儿童癌症幸存者研究(Childhood Cancer Survivor Study, CCSS)。

社会心理结果包括了心理上的苦恼、焦虑、抑郁、躯体症状、对癌症复发的恐惧、对面部容貌的满意度、创伤后生长和创伤后应激综合征;未患癌症CCSS的兄弟姐妹被作为对照组。共有470名RB幸存者和2820名CCSS兄弟姐妹参与此次研究,在研究时的两组平均年龄分别为43.3和33.2岁。经过社会人口因素的校正,RB幸存者相对于对照组并没有显著的更高比例的出现抑郁、躯体症状、苦恼或者焦虑。尽管RB幸存者有着更高的报道创伤后应激综合征的可能性,但是经过研究发现470人中只有5人符合创伤后应激综合征的条件。在幸存者中,有慢性医疗情况但是并不增加心理问题的可能性。双侧RB幸存者比单侧幸存者更有可能出现对癌症复发的恐惧,并且担心自己的子女也会被诊断出RB。但是两侧的RB幸存者并不比单侧患者更多报道抑郁、焦虑或者躯体症状。

此次研究表明,大多数RB幸存者的社会心理功能并不比未患癌症者差。此外,双侧和单侧RB幸存者似乎患心理综合征的情况相似。

原始出处:

Jennifer S. Ford ET AL. Psychosocial Outcomes in Adult Survivors of Retinoblastoma. Published Ahead of Print on September 28, 2015 as 10.1200/JCO.2014.60.5733

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    2015-10-16 lidong40
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    2015-10-02 zutt
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    2015-09-30 lovetcm

    以往肿瘤的研究很少关注的心理健康,实际上,肿瘤对于心理的影响,可能直接影响到他的治疗以及患者的预后

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