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Eur Raidol:肾病综合征患者发生急性肾损伤能不能让增强CT检查背黑锅?

2017-11-27 shaosai MedSci原创

本研究旨在验证是否经静脉进行碘剂对比剂CT增强检查会增加肾病综合征患者发生急性肾损伤(AKI)的风险,并将结果发表在Eur Raidol上。

本研究旨在验证是否经静脉进行碘剂对比剂CT增强检查会增加肾病综合征患者发生急性肾损伤(AKI)的风险,并将结果发表在Eur Raidol上。

本研究共纳入了701例患有肾病综合征并行增强CT的患者,对照组包括1053例患有肾病综合征而未行增强CT检查的患者。利用3或10个变量的两种不懂1:1倾向得分匹配模型分析每例患者的估计肾小球滤过率(eGFR)。评价两组CT检查后AKI的发生率并与标准AKI诊断标准和急性肾损伤网络专家组(AKIN)标准进行比较。

经过匹配3个变量后,在强化组与非强化组AKI的发生率为2.7% vs 2.5%(常规AKI诊断标准)、4.2% vs. 6.7% (AKIN 标准)(p = 1.00、0.05)。在匹配10个变量后,在强化组与非强化组AKI的发生率为3.1% vs. 2.6% (常规 AKI诊断标准)、4.1% vs. 7.4% (AKIN 标准) (p = 0.72、0.03)。每个eGFR亚组的AKI发生率在强化组并不比非强化组高(最小p = 0.46)。

本研究表明,在大型人群研究中,经静脉注射对比剂增强CT检查并不是肾病综合征患者发生AKI的危险因素。

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    2018-06-07 tongyongming
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    2018-10-29 wjywjy
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    2017-11-29 kzlchina
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    2017-11-27 shaosai

    好好学习天天向上

    0

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    2017-11-27 执着追梦

    学习.谢谢分享

    0

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