Baidu
map

J Rheumatol:吸烟与系统性红斑狼疮之间的关联

2019-12-08 xiangting MedSci原创

当前吸烟状态与SLE风险有关。随着时间的推移,SLE患者的性别和年龄对SLE的风险没有显著影响。

吸烟与系统性红斑狼疮(SLE)风险之间的关系仍存在争议。此外,随着时间推移吸烟人群人口学的变化对SLE风险的影响尚未得到正式解决。这项研究旨在通过最新的荟萃分析来研究吸烟与SLE风险之间的关联。

在计算机数据库中使用关键词狼疮吸烟香烟环境自身免疫结缔组织病进行文献检索,以查找解决吸烟与患SLE之间关联的研究。通过计算当前吸烟者与从不吸烟者、和既往吸烟者与从不吸烟者之间的对数比值比(OR)进行贝叶斯荟萃分析。计算了平均对数ORs(随后转换为ORs)及其对应的95%可信区间(CI)。通过多元荟萃回归分析了发表时间、SLE患者性别和年龄对效应大小的影响。

12项研究符合入组条件,共包括3,234名发展为SLE的个体和288,336名对照,对数据进行汇总显示,出现SLE与当前吸烟状态存在显著关联(OR 1.5495CI [1.062.25]),而出现SLE与既往吸烟状态之间仅有非显著的关联趋势(OR 1.3995CI [0.952.08])。发表时间、SLE患者性别和平均年龄不能解释效应大小的异质性。

当前吸烟状态与SLE风险有关。随着时间的推移,SLE患者的性别和年龄对SLE的风险没有显著影响。

原始出处:

Monica Hui Yan Chua. Association Between Cigarette Smoking and Systemic Lupus Erythematosus - an Updated Multivariate Bayesian Metaanalysis. J Rheumatol. December 2019.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2017189, encodeId=d8c5201e18922, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Wed Sep 16 03:15:00 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387377, encodeId=2120138e3773a, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436237, encodeId=6bf0143623e5b, content=<a href='/topic/show?id=22f8e71238d' target=_blank style='color:#2F92EE;'>#红斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77123, encryptionId=22f8e71238d, topicName=红斑)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=376694, encodeId=907c3e66945e, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sun Dec 08 11:50:49 CST 2019, time=2019-12-08, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2017189, encodeId=d8c5201e18922, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Wed Sep 16 03:15:00 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387377, encodeId=2120138e3773a, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436237, encodeId=6bf0143623e5b, content=<a href='/topic/show?id=22f8e71238d' target=_blank style='color:#2F92EE;'>#红斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77123, encryptionId=22f8e71238d, topicName=红斑)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=376694, encodeId=907c3e66945e, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sun Dec 08 11:50:49 CST 2019, time=2019-12-08, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2017189, encodeId=d8c5201e18922, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Wed Sep 16 03:15:00 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387377, encodeId=2120138e3773a, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436237, encodeId=6bf0143623e5b, content=<a href='/topic/show?id=22f8e71238d' target=_blank style='color:#2F92EE;'>#红斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77123, encryptionId=22f8e71238d, topicName=红斑)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=376694, encodeId=907c3e66945e, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sun Dec 08 11:50:49 CST 2019, time=2019-12-08, status=1, ipAttribution=)]
    2019-12-10 zhouqu_8
  4. [GetPortalCommentsPageByObjectIdResponse(id=2017189, encodeId=d8c5201e18922, content=<a href='/topic/show?id=9760e69058c' target=_blank style='color:#2F92EE;'>#系统性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76905, encryptionId=9760e69058c, topicName=系统性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2b9b368, createdName=qingrejiedu, createdTime=Wed Sep 16 03:15:00 CST 2020, time=2020-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1387377, encodeId=2120138e3773a, content=<a href='/topic/show?id=8a3a6814425' target=_blank style='color:#2F92EE;'>#狼疮#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68144, encryptionId=8a3a6814425, topicName=狼疮)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a6e2500005, createdName=sunrural_42825357, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1436237, encodeId=6bf0143623e5b, content=<a href='/topic/show?id=22f8e71238d' target=_blank style='color:#2F92EE;'>#红斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77123, encryptionId=22f8e71238d, topicName=红斑)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Tue Dec 10 02:15:00 CST 2019, time=2019-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=376694, encodeId=907c3e66945e, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160304/IMG56D94856B1B5D6405.jpg, createdBy=27931687771, createdName=一个字-牛, createdTime=Sun Dec 08 11:50:49 CST 2019, time=2019-12-08, status=1, ipAttribution=)]
    2019-12-08 一个字-牛

    学习了谢谢分享

    0

相关资讯

Arthritis Rheumatol:羟氯喹血药浓度可以预测羟氯喹视网膜病变

这项研究数据证明了羟氯喹血药水平在预测视网膜病变中的实用性。

以 HELLP 综合征首发的系统性红斑狼疮1 例

患者, 29 岁,因孕 31+5周,头痛 6 小时,于 2018 年 7 月 31 日入深圳市人民医院产科。末次月经 2017 年 12 月 20 日,预 产期 2018 年 9 月 27 日。停经 30+天自测尿 hCG( +) ,孕 4+月 自觉胎动。孕 12+周于外院建立围产保健手册,并定期规律产 前检查,建册时基础 BP 110/70 mmHg,随机尿蛋白阴性,唐氏 筛查低风险,地中海贫血

系统性红斑狼疮(SLE)如何减激素?专家:两大建议要牢记

激素对于系统性红斑狼疮(SLE)患者来说再熟悉不过了,激素作为常规治疗中不可缺少的药物,对迅速控制病情起到重要作用。但长期使用激素带来的副作用,如发胖、脱发、痤疮、骨质疏松、感染等,让多数处于美好年华的女性患者对它避之不及。“SLE如何减激素?”成为每个SLE患者最为关注的问题之一。作为具有丰富治疗经验的医师,中国医师协会风湿免疫分会青委会副主任委员、中山大学附属第三医院风湿免疫科副主任医师林智明

2019 EULAR/ACR标准:系统性红斑狼疮的分类标准

2019年9月,欧洲抗风湿病联盟(EULAR)联合美国风湿病学会(ACR)共同发布了系统性红斑狼疮的分类标准,新的分类标准是在多学科和国际方面的投入下,采用严格的方法制定,具有极好的敏感性和特异性。

Arthritis Rheumatol:使用系统性狼疮国际合作诊所虚弱指数(SLICC-FI)预测SLE损害

SLICC-FI可以预测偶发性SLE的损害,这进一步支持将SLICC-FI作为SLE的有效健康指标。

Arthritis Rheumatol:乌司奴单抗治疗系统性红斑狼疮的1年疗效和安全性

乌司奴单抗在1年内对SLE患者持续有效,其安全性与其他适应症一致。

Baidu
map
Baidu
map
Baidu
map