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Am J Gastroenterol:这些治疗可以降低息肉切除术后出血风险

2016-08-09 Seven L 译 MedSci原创

目的:通过网状meta评估各种预防治疗对结直肠息肉切除术后出血的预防疗效。方法:纳入所有相关的随机对照试验;预防性治疗类型分为机械疗法、肾上腺素生理盐水注射疗法、凝固疗法、联合治疗(前三种疗法中的两种或三种联合治疗)或无预防性治疗。对所有预防性治疗进行了贝叶斯网状荟萃分析。结果:对15项研究包括3462例患者进行了荟萃分析。与无预防性治疗组患者相比,肾上腺素生理盐水注射疗法(RR (95% CrI

目的:通过网状meta评估各种预防治疗对结直肠息肉切除术后出血的预防疗效。

方法:纳入所有相关的随机对照试验;预防性治疗类型分为机械疗法、肾上腺素生理盐水注射疗法、凝固疗法、联合治疗(前三种疗法中的两种或三种联合治疗)或无预防性治疗。对所有预防性治疗进行了贝叶斯网状荟萃分析。

结果:对15项研究包括3462例患者进行了荟萃分析。与无预防性治疗组患者相比,肾上腺素生理盐水注射疗法(RR (95% CrI)=0.32 (0.11-0.67))和机械疗法(RR (95% CrI)=0.13 (0.03-0.37))在预防早期息肉切除术后出血,具有优越性(中等质量的证据)。

联合疗法与注射疗法(RR (95% CrI)=0.35 (0.10-1.00))或机械疗法(RR (95% CrI)=0.88 (0.23-3.00))相比,没有差异性。

对于晚期出血,没有发现可降低风险的有效预防治疗方式(与无预防性治疗组患者相比)。

结论:机械疗法和肾上腺素生理盐水注射疗法可有效降低结直肠息肉切除术后出血风险;但是对于晚期出血,与无预防性治疗组患者相比,没有发现有效预防治疗方式。

原始出处:

Park CH.et al.Comparison of Efficacy of Prophylactic Endoscopic Therapies for Postpolypectomy Bleeding in the Colorectum: A Systematic Review and Network Meta-Analysis.Am J Gastroenterol. 2016 Jul 12. doi: 10.1038/ajg.2016.287. [Epub ahead of print]


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    2017-04-09 许安
  3. 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objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-09-23 1e10c84am36(暂无匿称)

    深度好文,值得学习

    0

  5. 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content=深度好文,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Aug 26 09:01:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=99138, encodeId=726c99138e2, content=机械疗法是否钛夹夹闭?, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36cd1931808, createdName=玲儿呢丫丫, createdTime=Tue Aug 16 13:07:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98487, encodeId=f82a9848ea1, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-09-05 李东泽

    很好,不错,以后会多学习

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
  7. 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content=深度好文,赞一个!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Fri Aug 26 09:01:00 CST 2016, time=2016-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=99138, encodeId=726c99138e2, content=机械疗法是否钛夹夹闭?, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36cd1931808, createdName=玲儿呢丫丫, createdTime=Tue Aug 16 13:07:00 CST 2016, time=2016-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=98487, encodeId=f82a9848ea1, content=继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-08-28 stead

    学习到了

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-08-26 ylzr123

    深度好文,赞一个!!!

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-08-16 玲儿呢丫丫

    机械疗法是否钛夹夹闭?

    0

  10. 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objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Sun Aug 14 15:57:00 CST 2016, time=2016-08-14, status=1, ipAttribution=)]
    2016-08-14 doctorJiangchao

    继续关注

    0

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  息肉切除术后迟发性出血是一种罕见但严重的并发症。近日,来自韩国的研究者Jeong Ho Kim发表论文,旨在确定息肉切除术后发展成迟发性出血的风险因素。该研究指出,息肉的大小、形状和位置代表结肠镜下息肉切除术后迟发性出血的实质性风险因素。该文发表在2013年第28卷第4期《胃肠病学与肝脏病学杂志》上。   这是一项对接受结肠镜下息肉切除术后发展为迟发性便血患者的回顾性病例

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