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Neurology：青春期BMI增加与成人卒中风险之间的相关性分析！

2017-06-29 xing.T MedSci原创

青春期BMI增加卒中风险
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由此可见，青春期BMI增加与成年男性的缺血性卒中和脑出血风险相关。研究人员推测在青春期BMI增加较大会增加成人卒中的风险，至少部分是通过增加血压来实现。

近日，神经病学领域权威取杂志Neurology上发表了一篇系统评价文章，研究人员旨在评估青春期前儿童体重指数（BMI）以及青春期BMI变化值，2个不同的发育BMI参数，对成年男性卒中风险的作用。

在瑞典哥德堡人群为基础的研究中，这些受试者均出生于1945年至1961年，且都有在8岁时的儿童BMI和青春期BMI变化值（20岁的BMI值减去8岁时的BMI）的信息，并随访至2013年12月（n=37669）。卒中事件的信息来自于高质量的国家登记中心（918例首次卒中事件患者、672例缺血性卒中事件患者和207例脑出血事件患者）。

青春期BMI增加（每增加1个SD的风险比为1.21，95%可信区间为1.14-1.28），而不是儿童BMI，与成人卒中的风险独立相关。亚组分析显示青春期BMI增加与缺血性卒中事件（每增加1个SD的风险比为1.19；95%可信区间为1.11-1.28）和脑出血事件（每增加1个SD的风险比为1.29；95%可信区间为1.15-1.46）。青春期BMI增加较大与成年高血压的风险密切相关（每增加1个SD的比值比为1.35；95%可信区间为1.32-1.39）。

由此可见，青春期BMI增加与成年男性的缺血性卒中和脑出血风险相关。研究人员推测在青春期BMI增加较大会增加成人卒中的风险，至少部分是通过增加血压来实现。

原始出处：

Claes Ohlsson,et al. BMI increase through puberty and adolescence is associated with risk of adult stroke. Neurology. 2017. http://dx.doi.org/10.1212/WNL.0000000000004158

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    2018-03-20 shenxlcyp

    #相关性#

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    2017-07-27 yinhl1978

    #Neurol#

    0

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    2017-07-12 jacob9231

    学习了谢谢分享

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createdTime=Thu Jun 29 23:16:18 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216829, encodeId=2d6e216829ed, content=学习了，受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Jun 29 21:41:19 CST 2017, time=2017-06-29, status=1, ipAttribution=)]
    2017-07-03 jacob9231

    学习了谢谢分享

    0

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createdTime=Thu Jun 29 23:16:18 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216829, encodeId=2d6e216829ed, content=学习了，受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Jun 29 21:41:19 CST 2017, time=2017-06-29, status=1, ipAttribution=)]
    2017-07-01 zhzhxiang

    #青春期#

    0

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createdTime=Thu Jun 29 23:16:18 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216829, encodeId=2d6e216829ed, content=学习了，受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Jun 29 21:41:19 CST 2017, time=2017-06-29, status=1, ipAttribution=)]
    2017-07-01 仁心济世

    #卒中风险#

    0

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    2017-07-01 anminleiryan

    #相关性分析#

    0

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    2017-06-30 184****9840

    学习了谢谢分享

    0

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createdTime=Thu Jun 29 23:16:18 CST 2017, time=2017-06-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=216829, encodeId=2d6e216829ed, content=学习了，受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Thu Jun 29 21:41:19 CST 2017, time=2017-06-29, status=1, ipAttribution=)]
    2017-06-29 lovetcm

    越年轻越肥胖危险就越高

    0

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    2017-06-29 清风拂面

    学习了，受益匪浅

    0

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