Baidu
map

Circ-Heart Fail:新发心衰老年患者冠状动脉疾病检测的意义

2020-03-25 MedSci原创 MedSci原创

大多数新发心衰住院患者在住院期间或住院前后90天内均未接受CAD检测。LVEF≤40%的患者CAD检测率较高,但总体仍较低。

当前的指南建议对新发心衰(HF)患者的潜在心脏病和可逆性疾病进行评估,目前对新发HF患者冠状动脉疾病(CAD)的检测数据十分有限。

近日,心血管领域权威杂志Circ-Heart Fail上发表了一篇研究文章,研究人员使用了医疗保险索赔相关的HF登记中心数据进行了一项观察性队列研究。所有患者年龄≥65岁,在2009-2015年期间因新发HF住院。研究人员从登记处收集了受试者的左心室射血分数(LVEF)、既往HF病史和住院CAD检测结果,以及在HF住院前90天到住院后90天进行CAD检测的结果。

在17185例新发HF患者中,6672例(39%)接受了CAD检测,其中3997例(23%)受试者在住院期间接受了CAD检测。CAD的检测结果因LVEF的不同而异:HF患者中有53%的个体EF降低 (LVEF≤40%),HF患者中有42%的个体EF处于临界值 (LVEF为41%-49%),31%的HF患者EF正常 (LVEF≥50%)。经过多变量调整后,接受CAD检测的患者较未接受CAD检测的患者更年轻,且更有可能是男性、有吸烟史、高脂血症、心衰(射血分数降低或射血分数处于临界值(所有P<0.05)。

由此可见,大多数新发心衰住院患者在住院期间或住院前后90天内均未接受CAD检测。LVEF≤40%的患者CAD检测率较高,但总体仍较低。

原始出处:

Kyle D. O’Connor,et al.Testing for Coronary Artery Disease in Older Patients With New-Onset Heart Failure Findings From Get With The Guidelines–Heart Failure.Circulation:heart failure. 2020.https://www.ahajournals.org/doi/10.1161/CIRCHEARTFAILURE.120.006963

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1799435, encodeId=3a121e99435f7, content=<a href='/topic/show?id=eb5ae068750' target=_blank style='color:#2F92EE;'>#疾病检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70687, encryptionId=eb5ae068750, topicName=疾病检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3679417, createdName=feather78, createdTime=Sun Sep 06 17:46:25 CST 2020, time=2020-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252940, encodeId=3a8c1252940c2, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357454, encodeId=4c3c135e454a8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563269, encodeId=617e156326962, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1799435, encodeId=3a121e99435f7, content=<a href='/topic/show?id=eb5ae068750' target=_blank style='color:#2F92EE;'>#疾病检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70687, encryptionId=eb5ae068750, topicName=疾病检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3679417, createdName=feather78, createdTime=Sun Sep 06 17:46:25 CST 2020, time=2020-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252940, encodeId=3a8c1252940c2, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357454, encodeId=4c3c135e454a8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563269, encodeId=617e156326962, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1799435, encodeId=3a121e99435f7, content=<a href='/topic/show?id=eb5ae068750' target=_blank style='color:#2F92EE;'>#疾病检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70687, encryptionId=eb5ae068750, topicName=疾病检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3679417, createdName=feather78, createdTime=Sun Sep 06 17:46:25 CST 2020, time=2020-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252940, encodeId=3a8c1252940c2, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357454, encodeId=4c3c135e454a8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563269, encodeId=617e156326962, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
    2020-03-27 zhaojie88
  4. [GetPortalCommentsPageByObjectIdResponse(id=1799435, encodeId=3a121e99435f7, content=<a href='/topic/show?id=eb5ae068750' target=_blank style='color:#2F92EE;'>#疾病检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70687, encryptionId=eb5ae068750, topicName=疾病检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3679417, createdName=feather78, createdTime=Sun Sep 06 17:46:25 CST 2020, time=2020-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1252940, encodeId=3a8c1252940c2, content=<a href='/topic/show?id=463230886b8' target=_blank style='color:#2F92EE;'>#冠状动脉疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30886, encryptionId=463230886b8, topicName=冠状动脉疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357454, encodeId=4c3c135e454a8, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563269, encodeId=617e156326962, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Fri Mar 27 09:46:25 CST 2020, time=2020-03-27, status=1, ipAttribution=)]
    2020-03-27 slcumt

相关资讯

将PRO纳入心衰患者预后评估:来自GISSI-HF研究的推荐

患者报告结局(PRO)可反应心力衰竭患者自身状况,并为预后提供重要信息,然而PRO尚未作为临床常规资料进行收集。为了探讨PRO是否应该纳入心力衰竭患者的预后评估,意大利心肌梗死与心力衰竭生存注册研究(GISSI-HF)研究组采用前瞻性队列研究,对符合纳入标准的心力衰竭患者随访3.3年,从而评价心力衰竭疾病特异性PRO量表之一的堪萨斯城心肌病问卷(KCCQ)对心力衰竭患者死亡和再住院的预测价值,以对

JACC:心梗和心衰再入院与死亡率的变化情况

本研究旨在评估加拿大安大略急性心肌梗死(AMI)和心衰(HF)后再入院率和死亡率的时间趋势,在安大略省,减少医院再入院率并没有政策激励。本研究纳入了2006-2017年65岁以上的AMI和HF住院患者,主要终点事件是30天的再入院率和出院后死亡率。最终共纳入分析了152808名AMI和223283名HF住院患者,安大略的AMI住院率在2006-2017年间降低了32%,HF住院率降低了9.1%。对

新冠肺炎致死真相:肾衰、心衰发生率远高于SARS,或与ACE2受体分布有关?

第三军医大学谌小维、周艺、鄢俊安及中国科学院苏州生物医学工程技术研究所贾宏博团队在医学预印本网站Medrxiv上发表结果,发现新冠肺炎的新临床特征:病例中肾功能衰竭的发生率远高于SARS,并强烈建议及时检测重症患者的肾功能,可能是大大降低死亡比例的关键。

JACC:多种新生物标志物可预测心衰伴保留型射血分数患者的预后

心衰伴保留型射血分数(HFpEF)尚需要更好的风险分层策略,本研究的目的是评估靶向血浆多标记方法在增强HFpEF表型特征和风险预测中的价值。

Eur J Heart Fail:血钾水平与射血分数降低心衰患者预后之间的关联

在这个全国性的登记研究中,血钾和死亡率之间的关系呈U形,最佳血钾值为4.2mmol/L。经过多变量调整后,低钾血症与长期死亡率增加相关,而高钾血症与短期死亡率增加相关。

Heart:相距30岁的两个男性队列心衰发生率和危险因素比较

由此可见,1943年出生的男子在50岁以后患HF的风险是30年前出生男性的一半。AF、肥胖症、缺血性心脏病、糖尿病和高血压仍然是HF的重要危险因素。

Baidu
map
Baidu
map
Baidu
map