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OCC2018丨崔锦钢:2016~2017年分叉病变技术领域新进展

2018-06-05 国际循环编辑部 国际循环

2018年6月2日,在OCC 2018会议上,中国医学科学院阜外医院崔锦钢教授从分支重要性评价及如何优化分叉病变治疗结局等几大方面概述了2016~2017年分叉病变治疗技术的最新进展及相关研究最新成果,让参会者对分叉病变的治疗有了更深入和全面的认识。

2018年6月2日,在OCC 2018会议上,中国医学科学院阜外医院崔锦钢教授从分支重要性评价及如何优化分叉病变治疗结局等几大方面概述了2016~2017年分叉病变治疗技术的最新进展及相关研究最新成果,让参会者对分叉病变的治疗有了更深入和全面的认识。

分支重要性评价——决定哪个分支更重要

一般来说,分支较少提供大面积心肌供血。对于分支的评价,影像学检查有助于我们评估分支的重要性和预测分支闭塞风险。COBIS注册登记研究对2004年1月~2006年6月17家医院成年分叉病变患者的分析显示,分支钙化、分支直径较大、围术期未应用氯吡格雷是分支禁闭(DS≥75%)的预测因素;真性分叉病变及分支直径较小则是防范严重挤压的预测因素。此外,斑块类型及所处部位也会影响分支闭塞风险。因此,临床实践中有必要对分支进行影像学及闭塞风险评估。

相关技术研究进展——探讨分叉病变优化治疗之路

回顾2016~2017年发布的分叉病变相关研究技术领域进展可见,Jailed导丝技术治疗冠状动脉分叉病变时导致不同程度的结构性损伤;与非聚合物涂层导丝相比,聚合物涂层导丝更不容易发生导丝回撤相关损伤,且能更有效地跨越分支开口。J-Reverse注册研究表明,针对分叉病变,与非对吻球囊技术(KBT)治疗相比,KBT虽增加分支夹层风险,但可在主要心脏不良事件发生率相当的情况下增加管腔获得,减少再狭窄的发生(11.0% vs. 29.7%)。



DKCRUSH V研究这一多中心随机临床试验比较了采用双对吻挤压术(DK Crush)及必要时分支支架术(Provisional stenting,PS)行药物洗脱支架置入术治疗左主干末端真性分叉病变的1年效果。结果发现,与PS技术相比,DK crush技术行PCI治疗左主干末端真性分叉病变的1年靶病变失败率更低。2018年最新发布的有关单支架策略与双支架策略治疗冠状动脉分叉病变的相关研究的荟萃分析显示,与双支架策略相比,单支架策略可能有助于降低长期全因死亡率。此外,对于优化分叉病变治疗,临床实践中医生有必要充分了解支架设计及特征,选择适宜尺寸的支架。

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    2018-06-07 zhaojie88
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    2018-06-06 三生有幸9135

    学习一下谢谢

    0

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    2018-06-05 清风拂面

    谢谢分享学习

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    2018-06-05 131****2916

    不错的文章值得推荐一下

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    2018-06-05 有备才能无患

    2018年6月2日.在OCC2018会议上.中国医学科学院阜外医院崔锦钢教授从分支重要性评价及如何优化分叉病变治疗结局等几大方面概述了2016~2017年分叉病变治疗技术的最新进展及相关研究最新成果.让参会者对分叉病变的治疗有了更深入和全面的认识.

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    2018-06-05 惠映实验室

    学习了.谢谢分享.

    0

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