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PET/CT用于胶质瘤的早期发现与生长监测文献分析

2011-04-02 MedSci原创 MedSci原创

PET/CT胶质瘤
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MedSci注：这篇文章比较简单，其特色在于“早”，作者采用动物模型，观察术后最早发现肿瘤的时间，以及行为学改变的相关性。如果在人体中也能发现类似的相关性，会更有价值。 　台湾长庚纪念医院神经外科的王（Wang TC）等研究发现，正电子发射体层摄影（PET）检查有助于发现早期大鼠胶质瘤，而传统的神经系统检查手段则有助于监测肿瘤的生长。论文2月12日在线发表于《神经肿瘤学杂志》（J&nb

MedSci注：这篇文章比较简单，其特色在于“早”，作者采用动物模型，观察术后最早发现肿瘤的时间，以及行为学改变的相关性。如果在人体中也能发现类似的相关性，会更有价值。 　台湾长庚纪念医院神经外科的王（Wang TC）等研究发现，正电子发射体层摄影（PET）检查有助于发现早期大鼠胶质瘤，而传统的神经系统检查手段则有助于监测肿瘤的生长。论文2月12日在线发表于《神经肿瘤学杂志》（J Neurooncol）。 　　恶性胶质瘤是最常见的颅内原发肿瘤，以广泛侵犯和进展迅速为特点。不断发展的动物影像学技术，使我们能够建立可靠的动物模型并且通过无创方式监测肿瘤生长，这对于研发新的治疗技术非常重要。 　　该研究应用传统的神经学检查手段以及18F-氟脱氧葡萄糖（18F-FDG ）PET技术来监测大鼠胶质瘤模型的肿瘤生长情况，用肢体运动和感觉试验来评估大鼠神经功能缺失情况，并分析大鼠神经行为改变与PET影像学表现及组织病理学数据的相关性。 　　结果为，在手术后7天时，PET影像上可清晰地观察到肿瘤存在。神经行为改变与PET影像学表现及组织病理学结果相关性良好。

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#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1725380, encodeId=9aa71e25380a8, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Nov 15 05:38:00 CST 2011, time=2011-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309654, encodeId=640513096545d, content=<a href='/topic/show?id=412114080d1' target=_blank style='color:#2F92EE;'>#PET/CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14080, encryptionId=412114080d1, topicName=PET/CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331001, encodeId=56d51331001a9, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331290, encodeId=82001331290ee, content=<a href='/topic/show?id=35e7593559a' target=_blank style='color:#2F92EE;'>#早期发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59355, encryptionId=35e7593559a, topicName=早期发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cb02500048, createdName=ms6832696159214430, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=)]
    2011-11-15 feather89

    #PE#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1725380, encodeId=9aa71e25380a8, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Nov 15 05:38:00 CST 2011, time=2011-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309654, encodeId=640513096545d, content=<a href='/topic/show?id=412114080d1' target=_blank style='color:#2F92EE;'>#PET/CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14080, encryptionId=412114080d1, topicName=PET/CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331001, encodeId=56d51331001a9, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331290, encodeId=82001331290ee, content=<a href='/topic/show?id=35e7593559a' target=_blank style='color:#2F92EE;'>#早期发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59355, encryptionId=35e7593559a, topicName=早期发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cb02500048, createdName=ms6832696159214430, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=)]
    2011-04-04 chaojitidian

    #PET/CT#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1725380, encodeId=9aa71e25380a8, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Nov 15 05:38:00 CST 2011, time=2011-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309654, encodeId=640513096545d, content=<a href='/topic/show?id=412114080d1' target=_blank style='color:#2F92EE;'>#PET/CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14080, encryptionId=412114080d1, topicName=PET/CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331001, encodeId=56d51331001a9, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331290, encodeId=82001331290ee, content=<a href='/topic/show?id=35e7593559a' target=_blank style='color:#2F92EE;'>#早期发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59355, encryptionId=35e7593559a, topicName=早期发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cb02500048, createdName=ms6832696159214430, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=)]
    2011-04-04 ms7514935887898259

    #PET#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1725380, encodeId=9aa71e25380a8, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Tue Nov 15 05:38:00 CST 2011, time=2011-11-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1309654, encodeId=640513096545d, content=<a href='/topic/show?id=412114080d1' target=_blank style='color:#2F92EE;'>#PET/CT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14080, encryptionId=412114080d1, topicName=PET/CT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=295c372, createdName=chaojitidian, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331001, encodeId=56d51331001a9, content=<a href='/topic/show?id=15e2140e438' target=_blank style='color:#2F92EE;'>#PET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14074, encryptionId=15e2140e438, topicName=PET)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI5PdY90y5Jib8FnPhCXTR2d9v3K17epNSwB2eb0vmXUldNJl2e72S4unZTAHLAojicdVSialTDFHAxA/132, createdBy=78d82500042, createdName=ms7514935887898259, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331290, encodeId=82001331290ee, content=<a href='/topic/show?id=35e7593559a' target=_blank style='color:#2F92EE;'>#早期发现#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59355, encryptionId=35e7593559a, topicName=早期发现)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9cb02500048, createdName=ms6832696159214430, createdTime=Mon Apr 04 12:38:00 CST 2011, time=2011-04-04, status=1, ipAttribution=)]
    2011-04-04 ms6832696159214430

    #早期发现#

    0

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