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FASEB J：儿童时期多摄入大豆蛋白成年期骨骼更健康

2016-10-16 MedSci MedSci原创

大豆蛋白　牛奶　骨骼　骨丧失
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近日，据发表于FASEB J的一项研究表明，生命早期多摄入大豆蛋白其成年期的骨骼更健康，且效果优于牛奶。研究称，早期的膳食营养中含有大量的大豆蛋白可防止成年期严重的骨丧失。该研究首次使用动物模型展示了生命早期大豆分离蛋白饮食对成人骨丧失的保护作用。研究人员选择了雌性幼鼠建立模型。一组大鼠喂养大豆分离蛋白饮食30天（从出生后24天到55天），然后切换到普通标准的啮齿动物饮食，直到6个月。然后对大鼠行

近日，据发表于FASEB J的一项研究表明，除了牛奶，生命早期多摄入大豆蛋白其成年期的骨骼更健康。研究称，早期的膳食营养中含有大量的大豆蛋白可防止成年期严重的骨丧失。该研究首次使用动物模型展示了生命早期大豆分离蛋白饮食对成人骨丧失的保护作用。

研究人员选择了雌性幼鼠建立模型。一组大鼠喂养大豆分离蛋白饮食30天（从出生后24天到55天），然后切换到普通标准的啮齿动物饮食，直到6个月。然后对大鼠行卵巢切除术以模拟绝经后骨丧失女性，以确定骨质流失量。第二组大鼠整个过程中喂以普通标的准啮齿动物饮食。然后对大鼠行卵巢切除术以模拟绝经后骨丧失女性，以确定骨质流失量。

结果发现，与对照组相比，喂以大豆分离蛋白的大鼠表现出明显的骨增量，虽然牛奶可以强壮骨骼，但是该研究表明大豆分离蛋白在成骨方面发挥着关键的作用，这一研究发现或对整个世界的儿童健康产生重大影响。

原始出处：

J.-R. Chen, O. P. Lazarenko, M. L. Blackburn, K. Shankar.Dietary factors during early life program bone formation in female rats. The FASEB Journal, 2016; DOI:10.1096/fj.201600703R

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    2017-07-05 12498dabm77暂无昵称

    #大豆蛋白#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2022415, encodeId=ee732022415fb, content=<a href='/topic/show?id=e0654401172' target=_blank style='color:#2F92EE;'>#大豆蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44011, encryptionId=e0654401172, topicName=大豆蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=78c32500188, createdName=12498dabm77暂无昵称, createdTime=Wed Jul 05 20:42:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057919, encodeId=41f1205e91973, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Fri Jan 20 09:42:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981362, encodeId=e46f19813626a, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Wed May 24 00:42:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149470, encodeId=5d5c1494e0c4, content=已经错过了这个时期，以后弥补, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20ee1960962, createdName=卡布奇诺joy, createdTime=Tue Oct 18 11:14:55 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148839, encodeId=efdf148839ad, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0df71676643, createdName=1de2495dm19(暂无匿称), createdTime=Sun Oct 16 17:35:10 CST 2016, time=2016-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148823, encodeId=a59e14882358, content=该让孩子多吃点豆子, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161013/IMG57FF1AB36A79C3246.jpg, createdBy=b0911965225, createdName=1e1487afm65(暂无匿称), createdTime=Sun Oct 16 15:12:01 CST 2016, time=2016-10-16, status=1, ipAttribution=)]
    2017-01-20 gracezdd

    #FAS#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2022415, encodeId=ee732022415fb, content=<a href='/topic/show?id=e0654401172' target=_blank style='color:#2F92EE;'>#大豆蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44011, encryptionId=e0654401172, topicName=大豆蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=78c32500188, createdName=12498dabm77暂无昵称, createdTime=Wed Jul 05 20:42:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057919, encodeId=41f1205e91973, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Fri Jan 20 09:42:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981362, encodeId=e46f19813626a, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Wed May 24 00:42:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149470, encodeId=5d5c1494e0c4, content=已经错过了这个时期，以后弥补, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20ee1960962, createdName=卡布奇诺joy, createdTime=Tue Oct 18 11:14:55 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148839, encodeId=efdf148839ad, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0df71676643, createdName=1de2495dm19(暂无匿称), createdTime=Sun Oct 16 17:35:10 CST 2016, time=2016-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148823, encodeId=a59e14882358, content=该让孩子多吃点豆子, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161013/IMG57FF1AB36A79C3246.jpg, createdBy=b0911965225, createdName=1e1487afm65(暂无匿称), createdTime=Sun Oct 16 15:12:01 CST 2016, time=2016-10-16, status=1, ipAttribution=)]
    2017-05-24 zhixianchen

    #儿童时期#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2022415, encodeId=ee732022415fb, content=<a href='/topic/show?id=e0654401172' target=_blank style='color:#2F92EE;'>#大豆蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44011, encryptionId=e0654401172, topicName=大豆蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=78c32500188, createdName=12498dabm77暂无昵称, createdTime=Wed Jul 05 20:42:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057919, encodeId=41f1205e91973, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Fri Jan 20 09:42:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981362, encodeId=e46f19813626a, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Wed May 24 00:42:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149470, encodeId=5d5c1494e0c4, content=已经错过了这个时期，以后弥补, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20ee1960962, createdName=卡布奇诺joy, createdTime=Tue Oct 18 11:14:55 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148839, encodeId=efdf148839ad, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0df71676643, createdName=1de2495dm19(暂无匿称), createdTime=Sun Oct 16 17:35:10 CST 2016, time=2016-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148823, encodeId=a59e14882358, content=该让孩子多吃点豆子, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161013/IMG57FF1AB36A79C3246.jpg, createdBy=b0911965225, createdName=1e1487afm65(暂无匿称), createdTime=Sun Oct 16 15:12:01 CST 2016, time=2016-10-16, status=1, ipAttribution=)]
    2016-10-18 卡布奇诺joy

    已经错过了这个时期，以后弥补

    0

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    2016-10-16 1de2495dm19(暂无匿称)

    继续学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2022415, encodeId=ee732022415fb, content=<a href='/topic/show?id=e0654401172' target=_blank style='color:#2F92EE;'>#大豆蛋白#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=44011, encryptionId=e0654401172, topicName=大豆蛋白)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=78c32500188, createdName=12498dabm77暂无昵称, createdTime=Wed Jul 05 20:42:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2057919, encodeId=41f1205e91973, content=<a href='/topic/show?id=3836e24819' target=_blank style='color:#2F92EE;'>#FAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7248, encryptionId=3836e24819, topicName=FAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=872f168, createdName=gracezdd, createdTime=Fri Jan 20 09:42:00 CST 2017, time=2017-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1981362, encodeId=e46f19813626a, content=<a href='/topic/show?id=f78e28313c1' target=_blank style='color:#2F92EE;'>#儿童时期#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28313, encryptionId=f78e28313c1, topicName=儿童时期)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Wed May 24 00:42:00 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=149470, encodeId=5d5c1494e0c4, content=已经错过了这个时期，以后弥补, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=20ee1960962, createdName=卡布奇诺joy, createdTime=Tue Oct 18 11:14:55 CST 2016, time=2016-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148839, encodeId=efdf148839ad, content=继续学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=96, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0df71676643, createdName=1de2495dm19(暂无匿称), createdTime=Sun Oct 16 17:35:10 CST 2016, time=2016-10-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=148823, encodeId=a59e14882358, content=该让孩子多吃点豆子, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161013/IMG57FF1AB36A79C3246.jpg, createdBy=b0911965225, createdName=1e1487afm65(暂无匿称), createdTime=Sun Oct 16 15:12:01 CST 2016, time=2016-10-16, status=1, ipAttribution=)]
    2016-10-16 1e1487afm65(暂无匿称)

    该让孩子多吃点豆子

    0

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