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AACR 2016:低脂肪饮食有助于绝经后女性避免致命性乳腺癌

2016-04-17 fsy 译 MedSci原创

根据在临床试验全体会议的一项研究,在美国癌症研究协会(AACR)年度会议发表的题为“乳腺癌转化临床试验”结果表明,与那些没有遵循饮食方案的女性相比,那些消耗低脂肪饮食的女性对于死于浸润性乳腺癌降的风险大约减少8年,生存率也有所提高。在近一个半世纪以前,膳食脂肪摄入量与乳腺癌预后之间的关联就被讨论过,但观察结果尚无定论。为了确定低脂肪膳食模式对乳腺癌的影响,洛杉矶生物医学研究所的医学博士Rowan

根据在临床试验全体会议上的一项研究,在美国癌症研究协会(AACR)年度会议发表的题为“乳腺癌转化临床试验”结果表明,与那些没有遵循饮食方案的女性相比,那些消耗低脂肪饮食的女性死于浸润性乳腺癌的风险大约减少8年,生存率也有所提高。

在近一个半世纪以前,膳食脂肪摄入量与乳腺癌预后之间的关联就被讨论过,但观察结果尚无定论。为了确定低脂肪膳食模式对乳腺癌的影响,洛杉矶生物医学研究所的医学博士Rowan Chlebowski和来自女性健康倡议的同事们进行了一项随机临床试验,对48835绝经后女性进行了随访分析。

这些女性年龄50-79岁,事先没有乳腺癌,具有正常乳房X线照片和正常的脂肪摄入。其中,19541名女性被置于一个低脂肪饮食与营养学家带领的小组,脂肪的摄入量减少能量的20%,增加水果,蔬菜和谷物的消耗。另外29294名女性遵循自己平时的饮食模式。

经过大约8年的低脂肪饮食,1767名女性被诊断患有乳腺癌。研究人员发现,饮食组的乳腺癌诊断后的总生存期要高:82% vs 78%。研究人员说,这种减少在某种程度上是由于,乳腺癌诊断后有更好的生存率。

“这是我们第一次审查了这个群体中乳腺癌后的死亡情况,我们发现,持续的低脂肪饮食增加了绝经后女性乳腺癌诊断后的存活率,”Chlebowski博士在会议上提出调查结果时说。“研究还表明,女性需要保持低脂肪饮食,以保持饮食干预的好处。”

研究人员还报告说,大多数乳腺癌的特点-包括大小、淋巴结状态、预后差的分布、三阴性癌症和HER2阳性的癌症-在两组女性中是相似的。但在饮食组有更少的孕激素受体阴性肿瘤(28.4% vs 33%)。此外,研究人员还指出,在饮食组中还有较低的心血管疾病死亡率。

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    2016-10-03 1e10c84am36(暂无匿称)

    深度好文,值得关注

    0

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    2016-09-11 1e10c84am36(暂无匿称)

    好文章,百姓也能从中学到好多医学知识

    0

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    2016-04-19 10518094zz
  5. [GetPortalCommentsPageByObjectIdResponse(id=139416, encodeId=c5fd13941699, content=深度好文,值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Oct 03 09:39:41 CST 2016, time=2016-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122016, encodeId=71b512201652, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 08:04:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257046, encodeId=0368125e04654, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1400337, encodeId=dd0f140033ee8, content=<a href='/topic/show?id=e7c018e7af' target=_blank style='color:#2F92EE;'>#ACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1877, encryptionId=e7c018e7af, topicName=ACR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19792261142, createdName=10518094zz, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526616, encodeId=388e15266168b, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551970, encodeId=211f15519e0e5, content=<a href='/topic/show?id=169c166430' target=_blank style='color:#2F92EE;'>#AACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1664, encryptionId=169c166430, topicName=AACR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6b2714248200, createdName=Luyuxie_14, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631512, encodeId=3acb16315120f, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=139416, encodeId=c5fd13941699, content=深度好文,值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Oct 03 09:39:41 CST 2016, time=2016-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122016, encodeId=71b512201652, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 08:04:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257046, encodeId=0368125e04654, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1400337, encodeId=dd0f140033ee8, content=<a href='/topic/show?id=e7c018e7af' target=_blank style='color:#2F92EE;'>#ACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1877, encryptionId=e7c018e7af, topicName=ACR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19792261142, createdName=10518094zz, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526616, encodeId=388e15266168b, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551970, encodeId=211f15519e0e5, content=<a href='/topic/show?id=169c166430' target=_blank style='color:#2F92EE;'>#AACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1664, encryptionId=169c166430, topicName=AACR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6b2714248200, createdName=Luyuxie_14, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631512, encodeId=3acb16315120f, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=)]
    2016-04-19 Luyuxie_14
  7. [GetPortalCommentsPageByObjectIdResponse(id=139416, encodeId=c5fd13941699, content=深度好文,值得关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Oct 03 09:39:41 CST 2016, time=2016-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122016, encodeId=71b512201652, content=好文章,百姓也能从中学到好多医学知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 08:04:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1257046, encodeId=0368125e04654, content=<a href='/topic/show?id=cdfce8879b1' target=_blank style='color:#2F92EE;'>#绝经#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78879, encryptionId=cdfce8879b1, topicName=绝经)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1400337, encodeId=dd0f140033ee8, content=<a href='/topic/show?id=e7c018e7af' target=_blank style='color:#2F92EE;'>#ACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1877, encryptionId=e7c018e7af, topicName=ACR)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=19792261142, createdName=10518094zz, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1526616, encodeId=388e15266168b, content=<a href='/topic/show?id=2fe6e88863a' target=_blank style='color:#2F92EE;'>#绝经后女性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78886, encryptionId=2fe6e88863a, topicName=绝经后女性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b55511745984, createdName=chenhongpeng, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551970, encodeId=211f15519e0e5, content=<a href='/topic/show?id=169c166430' target=_blank style='color:#2F92EE;'>#AACR#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1664, encryptionId=169c166430, topicName=AACR)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6b2714248200, createdName=Luyuxie_14, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1631512, encodeId=3acb16315120f, content=<a href='/topic/show?id=6395e888343' target=_blank style='color:#2F92EE;'>#绝经后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78883, encryptionId=6395e888343, topicName=绝经后)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32b921798518, createdName=zxxiang, createdTime=Tue Apr 19 12:28:00 CST 2016, time=2016-04-19, status=1, ipAttribution=)]
    2016-04-19 zxxiang
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