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婴儿接受麻醉会影响智商吗?

2016-09-10 佚名 爱唯医学网

费城儿童医院的研究人员对左心发育不良综合征的新生儿之研究报道,每年约10,000例新生儿因先天性心脏缺陷而接受全身麻醉,他们吸入越多的麻醉药,对其神经系统发展的影响将更大。此前研究认为患者神经发育不良与早产和遗传相关,Laura K. Diaz及其同事首次对婴儿心脏手术中,神经发育结果和可改变因素之一致性关系进行研究。该研究入组96例左心发育不良综合征(HLHS)或类似综合征的患者,这些患者于19

费城儿童医院的研究人员对左心发育不良综合征的新生儿之研究报道,每年约10,000例新生儿因先天性心脏缺陷而接受全身麻醉,他们吸入越多的麻醉药,对其神经系统发展的影响将更大。


此前研究认为患者神经发育不良与早产和遗传相关,Laura K. Diaz及其同事首次对婴儿心脏手术中,神经发育结果和可改变因素之一致性关系进行研究。


该研究入组96例左心发育不良综合征(HLHS)或类似综合征的患者,这些患者于1998至2003年期间使用了挥发性麻醉药(VAA)。患者接受一系列针对4-5岁的神经发育测试,包括全面智商(FSIQ)、言语智商(VIQ)、操作智商(PIQ)和处理速度。


这项研究表明,接受阶段性重建手术的HLHS儿童患者,从婴儿期开始使用的挥发性麻醉药越多,全面智商和言语智商的表现越差,该结果提示挥发性麻醉药的使用可能是不良神经发育结果的危险因素。


近年来,左心发育不良综合征新生儿的生存率显著提高,医师开始担心这些孩子后续遇到神经发育不良的问题。Diaz博士及其同事们承认,先前研究表明,如心肺流转术和住院时间,可能会影响孩子的神经发育,但结果不一致。反之,对于曾接受心脏手术的患者,患者的个体因素,如出生体重、种族和遗传疾病是神经发育的重大决定因素。


Diaz博士说其研究结果仅为初步,并未在实践中获得验证,需透过前瞻性随机对照多中心临床试验,继续阐明早期和重复使用挥发性麻醉药对小儿神经系统发育的影响。

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    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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    2016-09-13 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

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    2016-09-13 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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    2016-09-12 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

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    2016-09-12 晓辰

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寨卡病毒通常经蚊子叮咬传播。(图片来源:法新社)美国得克萨斯州卫生部门9日证实,近日该州哈里斯县一名女婴出生后不久因感染寨卡病毒死亡。这是得州发生的首例与寨卡病毒有关的死亡病例,也是美国首例婴儿感染寨卡病毒死亡病例。 得州卫生部当天称,这名女婴死于与寨卡病毒有关的小头症。她的母亲怀孕期间到萨尔瓦多旅行时感染寨卡病毒,最近的检测结果证实了这名女婴患了小头症。 今年7月,得州曾宣布

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2016年8月,美国胸科学会(ATS)发布了婴儿复发性或持续性喘息的诊断评估指南。婴幼儿喘息是一个常见的问题,美国胸科学会(ATS)指南制订委员会针对婴儿时期复发性和持续性喘息的诊断评估提出了几条推荐意见为临床医生提供指导。全文获取:下载地址:指南下载 (需要扣积分2分, 梅斯医学APP免积分下载)

Pediatrics:奶瓶的大小会影响宝宝的体重增长?

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β阻滞剂在怀孕期间被广泛应用于治疗高血压疾病。这些药物穿过胎盘,可能导致子宫内新生儿的生理变化。在一项全国性队列研究中,研究人员试图确定在母体内暴露β阻滞剂与新生儿低血糖和心动过缓风险之间的联系。 研究人员链接到2292116名活产婴儿的数据,他们的妈妈在2003年至2007年期间被招募参与此研究。研究人员检查了新生儿低血糖和心动过缓风险与在母体内暴露β受体阻断剂之间的联系。倾向评分匹配

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