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SCI REP:HALP对根治性膀胱全切术后膀胱癌患者的预后意义!

2018-01-15 xing.T MedSci原创 发表于威斯康星

由此可见,该研究确定了HALP的预测价值,并且为膀胱癌患者根治性膀胱全切术后提供了一个新的HALPA评分指标。

膀胱癌患者根治性膀胱切除术后结局有所不同,具有异质性。近日,Scientific reports杂志上发表了一篇研究文章,研究人员的目标是评估HALP(血红蛋白、白蛋白、淋巴细胞和血小板)的预后价值,并探讨膀胱癌根治性膀胱全切除术后患者预后的新指标。

在这项回顾性研究中,516例接受根治性膀胱切除术的膀胱癌患者被纳入研究。中位随访时间为37个月(2-99个月)。总生存率降低的危险因素包括年龄、高TNM分期、高美国麻醉医师(ASA)级别和低HALP评分。基于HALP的统计数据图预测准确率较高,相比于TNM分期(C指数为0.76±0.039 vs. 0.708±0.041)。通过将ASA分级和HALP结合,研究人员创建了一个新的HALPA指数评分,并且发现其是生存率降低的独立危险因素(HALPA评分=1,风险比为1.624,95%可信区间为1.139-2.314,P=0.007;HALPA评分=2,风险比为3.471,95%可信区间为1.861-6.472,P<0.001)。

由此可见,该研究确定了HALP的预测价值,并且为膀胱癌患者根治性膀胱全切术后提供了一个新的HALPA评分指标。

在线使用:膀胱癌根治性术后的预后评估(基于HALP的评分)

原始出处:

Ding Peng,et al. Prognostic significance of HALP (hemoglobin, albumin, lymphocyte and platelet) in patients with bladder cancer after radical cystectomy.Scientific reports. 2018. https://www.nature.com/articles/s41598-018-19146-y

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    2018-04-19 jiekemin
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    2018-01-28 大爰

    学习了谢谢分享!!

    0

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    2018-01-17 jeanqiuqiu
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    2018-01-16 大爰

    学习了谢谢分享!!

    0

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    2018-01-15 天涯183

    非常好的文章.学习了

    0

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