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JCO:医生应该告知晚期癌症患者的预后吗?

2015-10-10 赵洲 译 MedSci原创

 医生与晚期肿瘤患者讨论预后是最为重要,同样也是极富有挑战性的对话。对预后有准确的认识可以让晚期肿瘤患者在生命尽头更好的规划和作出知情照护决策。但是不幸的是,晚期癌症患者对于预后往往有许多错误的想法。医患之间的沟通障碍会导致许多误解,这不利于疾病的治疗等方面。因此有必要确定预后对话如何影响患者对寿命预期(life expectancy,LE)的理解、苦恼和医患关系。 为此,哈佛

医生与晚期肿瘤患者讨论预后是极为重要的,这同样也是极富有挑战性的对话。对预后有准确的认识可以让晚期肿瘤患者在生命尽头更好的规划和作出知情照护决策。

但是不幸的是,晚期癌症患者对于预后往往有许多错误的想法。医患之间的沟通障碍会导致许多误解,这不利于疾病的治疗等方面。因此有必要确定预后对话如何影响患者对寿命预期(life expectancy,LE)的理解、苦恼和医患关系。
 
为此,哈佛医学院等机构进行了一项多中心观测研究。此项研究共有590名转移性实体瘤患者参与,对这些患者进行随访直至离世。在基线时,研究人员对患者进行采访,调查他们的医生是否曾告知他们对预后的估计。此外,患者也估计了自己的预期寿命并且完成了对患者-医生间关系、苦恼、预设医疗指示和临终照护的偏好的评估。

这590人的中位生存期为5.4个月。其中71%希望能得知自己的寿命预期,但是只有17.6%患者放弃从医生口中得知了医生对自己的预后估计。在299名愿意估计他们的LE的患者中,那些放弃得知预后估计的患者相对于其他人提供了更加现实的估计值,他们对自己寿命的估计与实际生存时间更为接近。研究还发现,告知患者预后估计并不会使医患关系恶化、也不会让患者更难过或者焦虑。
 
此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。

原始出处:

Andrea C. Enzinger, Baohui Zhang, Deborah Schrag, and Holly G. Prigerson. Outcomes of Prognostic Disclosure: Associations With Prognostic Understanding, Distress, and Relationship With Physician Among Patients With Advanced Cancer. Published Ahead of Print on October 5, 2015 as 10.1200/JCO.2015.61.9239

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    2015-10-23 lidong40
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1891219, encodeId=fb37189121924, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Fri Oct 23 18:05:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983972, encodeId=a3cc19839e2fa, content=<a href='/topic/show?id=b53b5984ec1' target=_blank style='color:#2F92EE;'>#晚期癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59847, encryptionId=b53b5984ec1, topicName=晚期癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ba58436, createdName=马龙, createdTime=Mon Apr 25 15:05:00 CST 2016, time=2016-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289471, encodeId=e3f212894e143, content=<a href='/topic/show?id=cbb8e1356f7' target=_blank style='color:#2F92EE;'>#癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71356, encryptionId=cbb8e1356f7, topicName=癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Mon Oct 12 09:05:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38365, encodeId=dfc838365d1, content=应该的, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Oct 11 20:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38349, encodeId=4d8838349ef, content=当然应该, beContent=null, objectType=article, channel=null, level=null, likeNumber=206, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Oct 11 16:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38310, encodeId=f59138310e0, content=一切都应该慢慢来吧~, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Sat Oct 10 23:39:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38302, encodeId=71183830280, content=推荐大家读本书,《最好的告别》, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201205/e96b3d935daf4e258fba69d60175f0ab/b6d3ee4a3a414b8eafaf7c5e905937a2.jpg, createdBy=ad4b83208, createdName=vpssa, createdTime=Sat Oct 10 21:34:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38294, encodeId=3886382949e, content=此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38295, encodeId=735a38295ed, content=但是中国国情,文化可能并不一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=)]
    2015-10-11 三三五五

    应该的

    0

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    2015-10-11 stupidox

    当然应该

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1891219, encodeId=fb37189121924, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Fri Oct 23 18:05:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983972, encodeId=a3cc19839e2fa, content=<a href='/topic/show?id=b53b5984ec1' target=_blank style='color:#2F92EE;'>#晚期癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59847, encryptionId=b53b5984ec1, topicName=晚期癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ba58436, createdName=马龙, createdTime=Mon Apr 25 15:05:00 CST 2016, time=2016-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289471, encodeId=e3f212894e143, content=<a href='/topic/show?id=cbb8e1356f7' target=_blank style='color:#2F92EE;'>#癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71356, encryptionId=cbb8e1356f7, topicName=癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Mon Oct 12 09:05:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38365, encodeId=dfc838365d1, content=应该的, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Oct 11 20:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38349, encodeId=4d8838349ef, content=当然应该, beContent=null, objectType=article, channel=null, level=null, likeNumber=206, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Oct 11 16:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38310, encodeId=f59138310e0, content=一切都应该慢慢来吧~, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Sat Oct 10 23:39:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38302, encodeId=71183830280, content=推荐大家读本书,《最好的告别》, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201205/e96b3d935daf4e258fba69d60175f0ab/b6d3ee4a3a414b8eafaf7c5e905937a2.jpg, createdBy=ad4b83208, createdName=vpssa, createdTime=Sat Oct 10 21:34:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38294, encodeId=3886382949e, content=此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38295, encodeId=735a38295ed, content=但是中国国情,文化可能并不一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=)]
    2015-10-10 Jianghuiqin

    一切都应该慢慢来吧~

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1891219, encodeId=fb37189121924, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Fri Oct 23 18:05:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983972, encodeId=a3cc19839e2fa, content=<a href='/topic/show?id=b53b5984ec1' target=_blank style='color:#2F92EE;'>#晚期癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59847, encryptionId=b53b5984ec1, topicName=晚期癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ba58436, createdName=马龙, createdTime=Mon Apr 25 15:05:00 CST 2016, time=2016-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289471, encodeId=e3f212894e143, content=<a href='/topic/show?id=cbb8e1356f7' target=_blank style='color:#2F92EE;'>#癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71356, encryptionId=cbb8e1356f7, topicName=癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Mon Oct 12 09:05:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38365, encodeId=dfc838365d1, content=应该的, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Oct 11 20:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38349, encodeId=4d8838349ef, content=当然应该, beContent=null, objectType=article, channel=null, level=null, likeNumber=206, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Oct 11 16:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38310, encodeId=f59138310e0, content=一切都应该慢慢来吧~, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Sat Oct 10 23:39:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38302, encodeId=71183830280, content=推荐大家读本书,《最好的告别》, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201205/e96b3d935daf4e258fba69d60175f0ab/b6d3ee4a3a414b8eafaf7c5e905937a2.jpg, createdBy=ad4b83208, createdName=vpssa, createdTime=Sat Oct 10 21:34:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38294, encodeId=3886382949e, content=此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38295, encodeId=735a38295ed, content=但是中国国情,文化可能并不一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=)]
    2015-10-10 vpssa

    推荐大家读本书,《最好的告别》

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1891219, encodeId=fb37189121924, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Fri Oct 23 18:05:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983972, encodeId=a3cc19839e2fa, content=<a href='/topic/show?id=b53b5984ec1' target=_blank style='color:#2F92EE;'>#晚期癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59847, encryptionId=b53b5984ec1, topicName=晚期癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ba58436, createdName=马龙, createdTime=Mon Apr 25 15:05:00 CST 2016, time=2016-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289471, encodeId=e3f212894e143, content=<a href='/topic/show?id=cbb8e1356f7' target=_blank style='color:#2F92EE;'>#癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71356, encryptionId=cbb8e1356f7, topicName=癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Mon Oct 12 09:05:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38365, encodeId=dfc838365d1, content=应该的, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Oct 11 20:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38349, encodeId=4d8838349ef, content=当然应该, beContent=null, objectType=article, channel=null, level=null, likeNumber=206, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Oct 11 16:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38310, encodeId=f59138310e0, content=一切都应该慢慢来吧~, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Sat Oct 10 23:39:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38302, encodeId=71183830280, content=推荐大家读本书,《最好的告别》, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201205/e96b3d935daf4e258fba69d60175f0ab/b6d3ee4a3a414b8eafaf7c5e905937a2.jpg, createdBy=ad4b83208, createdName=vpssa, createdTime=Sat Oct 10 21:34:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38294, encodeId=3886382949e, content=此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38295, encodeId=735a38295ed, content=但是中国国情,文化可能并不一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=)]
    2015-10-10 medcardio

    此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1891219, encodeId=fb37189121924, content=<a href='/topic/show?id=25b0102e2df' target=_blank style='color:#2F92EE;'>#JCO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10272, encryptionId=25b0102e2df, topicName=JCO)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6da1120, createdName=lidong40, createdTime=Fri Oct 23 18:05:00 CST 2015, time=2015-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1983972, encodeId=a3cc19839e2fa, content=<a href='/topic/show?id=b53b5984ec1' target=_blank style='color:#2F92EE;'>#晚期癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59847, encryptionId=b53b5984ec1, topicName=晚期癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ba58436, createdName=马龙, createdTime=Mon Apr 25 15:05:00 CST 2016, time=2016-04-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1289471, encodeId=e3f212894e143, content=<a href='/topic/show?id=cbb8e1356f7' target=_blank style='color:#2F92EE;'>#癌症患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71356, encryptionId=cbb8e1356f7, topicName=癌症患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=10ba218, createdName=zgwhgch, createdTime=Mon Oct 12 09:05:00 CST 2015, time=2015-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38365, encodeId=dfc838365d1, content=应该的, beContent=null, objectType=article, channel=null, level=null, likeNumber=153, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Sun Oct 11 20:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38349, encodeId=4d8838349ef, content=当然应该, beContent=null, objectType=article, channel=null, level=null, likeNumber=206, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Sun Oct 11 16:31:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38310, encodeId=f59138310e0, content=一切都应该慢慢来吧~, beContent=null, objectType=article, channel=null, level=null, likeNumber=191, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Sat Oct 10 23:39:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38302, encodeId=71183830280, content=推荐大家读本书,《最好的告别》, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201205/e96b3d935daf4e258fba69d60175f0ab/b6d3ee4a3a414b8eafaf7c5e905937a2.jpg, createdBy=ad4b83208, createdName=vpssa, createdTime=Sat Oct 10 21:34:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38294, encodeId=3886382949e, content=此项研究对于临床肿瘤的治疗照护有着重要的意义。医生告知患者预后并不会恶化医患关系。这对于医患双方都有益处。, beContent=null, objectType=article, channel=null, level=null, likeNumber=201, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=38295, encodeId=735a38295ed, content=但是中国国情,文化可能并不一样, beContent=null, objectType=article, channel=null, level=null, likeNumber=113, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=96871613250, createdName=medcardio, createdTime=Sat Oct 10 20:45:00 CST 2015, time=2015-10-10, status=1, ipAttribution=)]
    2015-10-10 medcardio

    但是中国国情,文化可能并不一样

    0

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  英国伦敦大学心血管科学研究所的Coats CJ等人研究了心肺运动试验对于肥厚性心肌病患者预后的作用,研究成果发表在9月份 Circulation Heart failure期刊上。背景:  运动试验经常被用于肥厚型心肌病(HCM)患者,用来评估血压反应(一项心源性猝死的危险因素)。对运动气体交换变量的预后作用尚未可知。方法和结果:    1998年至20

Stroke:甘露醇不能改善急性脑出血预后

背景与目的:已六醇常被用于急性脑出血患者减少脑水肿,但是没有强大证据证实其有利。研究人员旨在确定已六醇对急性脑出血快速降压试验(INTERACT2)中受试者预后的影响。 方法:INTERACT2是一项国际性,开放性,盲终点,随机对照试验,共有2839名患有自发性脑出血(出血小于6h)的患者,并且对高收缩压患者进行紧急降压治疗(目标收缩压,1h内血压低于140 mm Hg)或者根据指南推荐(目标收缩

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