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J Gastroen Hepatol：白细胞清除术用于老年溃疡性结肠炎的治疗

2018-08-08 zhangfan MedSci原创

溃疡性结肠炎UC白细胞清除术
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本次真实世界研究证实了老年溃疡性结肠炎患者接受白细胞清除治疗的疗效及安全性

近年来老年溃疡性结肠炎 (UC)患者人数逐年增加，新的治疗手段对患者预后的改善效果也十分显著，白细胞清除术(LCAP)是一种体外UC治疗新方法。近日研究人员就LCAP对老年UC患者的疗效及安全性进行了考察。

本次研究人员是一项大型、前瞻性LCAP观察研究的事后分析，于2010-12年间在日本开展，116个医疗机构参与，总计847名患者参与，其中65岁以上老年患者75人(8.9%)。

分析发现，老年患者接受LCAP后未见严重不良事件，老年人群与一般人群接受治疗后不良事件率差异不显著，总体治疗后缓解率无显著差异。在非糖皮质激素治疗患者亚组中，老年组的缓解率显著高于非老年组(90.9% [20/22] vs 64.6% [135/209]， P = 0.02)。

本次真实世界研究证实了老年溃疡性结肠炎患者接受白细胞清除治疗的疗效及安全性。

原始出处：


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    2019-02-08 nymo

    #溃疡性#

    0

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    2018-11-26 许安

    #GAS#

    0

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    2019-06-09 ms24272190615788285182

    #AST#

    0

  4. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-31 zwjnj2

    学习学习天天学习

    0

  5. 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    2018-08-09 gwc384

    #EPA#

    0

  6. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-09 zwjnj2

    好好学习天天向上

    0

  7. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-09 哈哈869

    学习了

    0

  8. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-09 哈哈869

    学习了

    0

  9. 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encodeId=fe0733e530c4, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=106, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Thu Aug 09 12:28:59 CST 2018, time=2018-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337313, encodeId=224233e31392, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Wed Aug 08 13:36:18 CST 2018, time=2018-08-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-08 kafei

    学习了谢谢

    0

  10. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=337286, encodeId=34e533e286bc, content=作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKcmgibQ4oCrK7Z6f4CvMcs4k7QUGCkhopcGxvxaBfVciadECSIwaRVttllIOEKumpEaRrq5PoOUxow/0, createdBy=e3bb2081203, createdName=哈哈869, createdTime=Wed Aug 08 10:49:40 CST 2018, time=2018-08-08, status=1, ipAttribution=)]
    2018-08-08 哈哈869

    作者从极其专业的角度论述了大结节角的测量方法，使我们对影像学的专业诊断知识有了进一步的了解，多谢分享!

    0

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