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Am J Resp Crit Care:2型糖尿病患者的阻塞性睡眠呼吸暂停与视网膜病变!

2017-06-10 xing.T MedSci原创

由此可见,OSA与T2D患者STDR相关。OSA是是前/增生性DR进展的独立预测因子,CPAP治疗与减少前期/增殖DR相关,需要干预性研究来评估OSA治疗对STDR的影响。

近日,呼吸内科以及重症医学领域权威杂志Am J Resp Crit Care上发表了一篇研究文章,研究人员旨在评估阻塞性睡眠呼吸暂停(OSA)与2型糖尿病患者糖尿病视网膜病变(DR)之间的相关性,并进一步评估OSA是否与其进展相关。

研究人员在英国两所医院的糖尿病门诊进行了纵向研究。已知有任何呼吸系统疾病(包括OSA)的患者被排除在外。每只眼睛采用2x45度视网膜图像来评估DR。研究人员采用家用多通道心肺装置来进行OSA评估。

该研究共纳入了230例患者。威胁视力的DR(STDR)和OSA的患病率分别为36.1%和63.9%。在OSA患者中STDR的患病率较高,相比于那些没有OSA的患者(42.9% vs. 24.1%(P=0.004)。调整混杂因素后,OSA仍然与STDR独立相关(比值比为2.3,95%可信区间为1.1-4.9,P=0.04)。经过中位(IQR)随访43个月(37.0-51.0),OSA患者更可能发展前/增生性DR,相比于无OSA的患者(18.4% vs. 6.1%,P=0.02)。调整混杂因素后,OSA仍是前/增生性DR进展的独立预测因子(比值比为5.2,95%可信区间为1.2-23.0,P=0.03)。接受持续气道正压通气(CPAP)治疗的患者发生前/增殖性DR的可能性较少。

由此可见,OSA与T2D患者STDR相关。OSA是是前/增生性DR进展的独立预测因子,CPAP治疗与减少前期/增殖DR相关,需要干预性研究来评估OSA治疗对STDR的影响。

原始出处:


Quratul A Altaf, et al. Obstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes: A Longitudinal Study. AM J RESP CRIT CARE 2017.https://doi.org/10.1164/rccm.201701-0175OC.

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    2018-02-14 tomyang96
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    2017-06-12 zutt
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    2017-06-11 明天会更好!

    学习过了,很好值得分享!

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1989039, encodeId=ec441989039f2, content=<a href='/topic/show?id=246ee29858f' target=_blank style='color:#2F92EE;'>#睡眠呼吸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72985, encryptionId=246ee29858f, topicName=睡眠呼吸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3138208, createdName=zhanfl, createdTime=Fri Aug 18 23:49:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1696726, encodeId=99741696e26f7, content=<a href='/topic/show?id=d2e99e651e4' target=_blank style='color:#2F92EE;'>#阻塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=97651, encryptionId=d2e99e651e4, topicName=阻塞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a23129903429, createdName=tomyang96, createdTime=Wed Feb 14 02:49:00 CST 2018, time=2018-02-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1269888, encodeId=980412698885c, content=<a href='/topic/show?id=979690e33bd' target=_blank style='color:#2F92EE;'>#视网膜#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90733, encryptionId=979690e33bd, topicName=视网膜)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Mon Jun 12 02:49:00 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383300, encodeId=e77b1383300a7, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Mon Jun 12 02:49:00 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1413888, encodeId=f0c61413888f3, content=<a href='/topic/show?id=27b290e82f4' target=_blank style='color:#2F92EE;'>#视网膜病变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90782, encryptionId=27b290e82f4, topicName=视网膜病变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f7143034078, createdName=zhanfl, createdTime=Mon Jun 12 02:49:00 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474202, encodeId=a3d214e420268, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Mon Jun 12 02:49:00 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1596489, encodeId=5c5315964894a, content=<a href='/topic/show?id=70e4396491a' target=_blank style='color:#2F92EE;'>#呼吸暂停#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39649, encryptionId=70e4396491a, topicName=呼吸暂停)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e2a518392360, createdName=119337463, createdTime=Mon Jun 12 02:49:00 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209458, encodeId=163f2094582b, content=学习过了,很好值得分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sun Jun 11 17:16:51 CST 2017, time=2017-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209376, encodeId=ea0c2093e6e0, content=学习啦谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=119, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Sun Jun 11 11:10:31 CST 2017, time=2017-06-11, status=1, ipAttribution=)]
    2017-06-11 tanxingdoctor

    学习啦谢谢分享

    0

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