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Heart：慢性骨髓炎或为年轻人冠心病独立危险因素

2014-06-16 cath 编译 医学论坛网

慢性骨髓炎冠心病危险因素
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台湾学者探讨了慢性骨髓炎(COM)是否与冠心病(CHD)风险增加的相关性，结果表明，COM是CHD的独立危险因素，尤其是在年轻人群中。未来有必要进一步探索二者的潜在机制。论文2014年6月4日在线发表于《心脏》(Heart)杂志。该研究从台湾医疗保险库中确认15054例新诊断的COM患者，并随机选择60216例与其年龄和性别相匹配的对照组受试者，对比两组的CHD危险和发生率。研究时间为从入组至随访

台湾学者探讨了慢性骨髓炎(COM)是否与冠心病(CHD)风险增加的相关性，结果表明，COM是CHD的独立危险因素，尤其是在年轻人群中。未来有必要进一步探索二者的潜在机制。论文2014年6月4日在线发表于《心脏》(Heart)杂志。

该研究从台湾医疗保险库中确认15054例新诊断的COM患者，并随机选择60216例与其年龄和性别相匹配的对照组受试者，对比两组的CHD危险和发生率。研究时间为从入组至随访时首次发生心血管事件，包括CHD、死亡、撤销医疗保险或至2010年。利用Cox比例风险回归模型分析CHD危险。

结果显示，在随访的67 927人-年期间，COM队列的CHD整体发生率比无COM队列高1.95倍(16.66 对8.52/1000 人-年)。

控制年龄、性别和四种并存病(高血压、糖尿病、高脂血症和卒中)之后，COM队列的上述危险仍比对照组显著较高(校正危险比1.65，P<0.001)。

在年龄分层分析中，与老年人群相比，较年轻人群的COM与CHD风险相关性更强。

原始出处：

Lien-Cheng Hsiao1, Chih-Hsin Muo2, Yu-Ching Chen3, Che-Yi Chou4,5, Chun-Hung Tseng6,7, Kuan-Cheng Chang1,4.Increased risk of coronary heart disease in patients with chronic osteomyelitis: a population-based study in a cohort of 23 million.Heart June 4,2014 doi:10.1136/heartjnl-2014-305652.

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    2014-07-28 changjitao2009

    #慢性骨髓炎#

    0

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    2015-04-26 spoonycyy

    #独立危险因素#

    0

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    2014-06-18 zhaojie88

    #ART#

    0

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    2014-06-18 宋威

    #骨髓炎#

    0

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    2014-06-18 爆笑小医

    #HEART#

    0

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