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Clin Nutr:抗炎饮食可作为一种潜在的抑郁症干预措施

2020-09-28 MedSci原创 MedSci原创

有大量证据支持炎症在包括抑郁症在内的心理健康疾病的病理生理学中的作用。饮食模式已被证明可以调节炎症状态,从而突出了它们作为具有炎症基础的疾病的治疗工具的潜力。本文中,研究人员对目前的文献进行系统回顾和

有大量证据支持炎症在包括抑郁症在内的心理健康疾病的病理生理学中的作用。饮食模式已被证明可以调节炎症状态,从而突出了它们作为具有炎症基础的疾病的治疗工具的潜力。本文中,研究人员对目前的文献进行系统回顾和荟萃分析,探讨饮食的炎症潜力与抑郁症或抑郁症状的风险之间是否存在联系,研究结果已在线发表于Clin Nutr。

研究人员进行了系统性文献检索,以确定报告饮食的炎症潜能与抑郁症状风险或抑郁症诊断之间关联的研究。采用随机效应模型对效应大小进行元分析。此外,研究人员还进行了质量评估、出版偏倚、敏感性和亚组分析。

 

结果,纳入11项研究,包括101950名基线参与者(年龄范围:16-72岁),符合审查条件。与抗炎症饮食相比,促炎症饮食与抑郁症诊断或症状风险增加之间密切相关(OR:1.40,95%置信区间:1.21-1.62,P <0.001)。未发现发表偏倚;但一些研究异质性明显(I2 = 63%,P < 0.001)。亚组分析表明,研究异质性的主要来源是研究设计(横断面或纵向)和使用的效应测量(机率比、危险比或相对风险)。

综上所述,这些结果提供了促炎饮食和抑郁症风险之间的关联。因此,采取抗炎饮食可能是降低抑郁症风险和症状的有效干预或预防手段。

 

原始出处:

 

Katie TolkienSteven Bradburn, et al., An anti-inflammatory diet as a potential intervention for depressive disorders: A systematic review and meta-analysis. Clin Nutr. 2019 Oct;38(5):2045-2052. doi: 10.1016/j.clnu.2018.11.007. 

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    2020-11-12 Jessica

    促炎饮食 与抗炎饮食

    0

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    2020-10-18 ShawYuan

    什么是抗炎饮食?

    0

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    2020-09-30 cmuwisdom

    特别特别好

    0

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    2020-09-29 Psycho.Dr Du

    什么样的饮食结构是“抑炎饮食”呢?#抑郁症#

    0

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    2020-09-28 rayms

    越来越多的饮食方式进行被证明可干预慢病#抗炎饮食#

    0

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    2020-09-28 145cd6eem24暂无昵称

    👍👍

    0

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