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Neurology:老年女性脑血管病患者补充钙剂要当心啦!

2016-10-22 xing.T MedSci原创

由此可见,补充钙剂有可能增加老年女性脑血管病患者发生老年痴呆症的风险。

近日,神经病学领域权威杂志《neurology》上发表研究文章旨在明确补充钙剂与老年女性痴呆症发生与发展的关系。

在这个纵向以人口为基础的研究中,共纳入了700名未患痴呆的妇女,年龄在70–92岁。从2000–2001年起随访5年,她们接受全面的神经和躯体检查。447名参与者在研究之初进行了CT扫描,并收集了钙补充剂使用有否和剂量的信息,另外老年痴呆症根据DSM-III-R标准进行诊断。

研究者发现,相比于未补充钙剂的女性(n=602),钙剂补充治疗的妇女(n=98)发生痴呆症(比值比为2.10,95%可信区间为1.01–4.37,P=0.046)和卒中相关性痴呆亚型(血管性痴呆和混合性痴呆)(比值比为4.40,95%可信区间为1.54–12.61,P=0.006)的风险更高。在分层分析中,补充钙与有卒中病史(比值比为6.77,95%可信区间为1.36-33.75,P=0.020)或白质病变病史(比值比为2.99,95%可信区间为1.28-6.96,P=0.011)的老年痴呆症的发生有关,而在没有这些条件的患者中不存在这种相关性。

由此可见,补充钙剂有可能增加老年女性脑血管病患者发生老年痴呆症的风险。

原始出处:

Jürgen Kern, et al. Calcium supplementation and risk of dementia in women with cerebrovascular disease. 2016.Neurology.

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1644511, encodeId=a1071644511f1, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Jun 28 08:35:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999761, encodeId=97491999e61e2, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Dec 15 12:35:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150615, encodeId=5820150615d6, content=太可怕啦!那么女性骨质疏松怎么弄?, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Oct 23 15:04:18 CST 2016, time=2016-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150444, encodeId=45da150444da, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Sat Oct 22 22:25:24 CST 2016, time=2016-10-22, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1644511, encodeId=a1071644511f1, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Jun 28 08:35:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999761, encodeId=97491999e61e2, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Dec 15 12:35:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150615, encodeId=5820150615d6, content=太可怕啦!那么女性骨质疏松怎么弄?, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Oct 23 15:04:18 CST 2016, time=2016-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150444, encodeId=45da150444da, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Sat Oct 22 22:25:24 CST 2016, time=2016-10-22, status=1, ipAttribution=)]
    2016-12-15 yinhl1978
  3. [GetPortalCommentsPageByObjectIdResponse(id=1644511, encodeId=a1071644511f1, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Jun 28 08:35:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999761, encodeId=97491999e61e2, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Dec 15 12:35:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150615, encodeId=5820150615d6, content=太可怕啦!那么女性骨质疏松怎么弄?, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Oct 23 15:04:18 CST 2016, time=2016-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150444, encodeId=45da150444da, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Sat Oct 22 22:25:24 CST 2016, time=2016-10-22, status=1, ipAttribution=)]
    2016-10-23 meiliwuxian

    太可怕啦!那么女性骨质疏松怎么弄?

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1644511, encodeId=a1071644511f1, content=<a href='/topic/show?id=e3eb89e17fb' target=_blank style='color:#2F92EE;'>#血管病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89717, encryptionId=e3eb89e17fb, topicName=血管病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Wed Jun 28 08:35:00 CST 2017, time=2017-06-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1999761, encodeId=97491999e61e2, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Dec 15 12:35:00 CST 2016, time=2016-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150615, encodeId=5820150615d6, content=太可怕啦!那么女性骨质疏松怎么弄?, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=445f1740270, createdName=meiliwuxian, createdTime=Sun Oct 23 15:04:18 CST 2016, time=2016-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=150444, encodeId=45da150444da, content=学习了啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5e291719269, createdName=大旺旺, createdTime=Sat Oct 22 22:25:24 CST 2016, time=2016-10-22, status=1, ipAttribution=)]
    2016-10-22 大旺旺

    学习了啊

    0

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